21/10/2025
18 Reasons EMF Causes Alzheimer's Disease
The findings documented in this review are as follows:
1. The calcium hypothesis of Alzheimer’s disease (AD) argues that increased intracellular calcium ([Ca2+]i) is the central cause of AD.
2. The primary mechanism of action of EMFs is the activation of VGCCs, with such activation producing rapid, in some cases almost instantaneous, increases in [Ca2+]i.
3. Excessive [Ca2+]i causes each of the following specific and nonspecific important AD effects: Elevated levels of Aβ; elevated levels of APP; hyperphosphorylated tau protein and consequent neurofibrillary tangles; lowered memory function produced in part by lowered synaptic activity, including the disappearance of dendritic spines; increased apoptotic and autophagic cell death.
4. AD may be caused, in part, by a vicious cycle with excessive [Ca2+]i causing excessive Aβ, which produces, in turn, excessive [Ca2+]i.
5. EMF exposures in animal models of AD or neurodegeneration produce still additional changes that have roles in producing the changes described immediately above: lowered miR107, increased BACE1, elevated LC3-II, oxidative stress, deformed synaptic spines and bouton formation.
6. Genetic and pharmacological studies show that VGCC activity itself has important role in causing AD. VGCC activity may be important not only for producing excessive [Ca2+]i but also because of direct VGCC protein-protein interactions impacting synaptic function.
7. The two main pathways of action activated by [Ca2+]i producing pathophysiological effects, excessive calcium signaling and the peroxynitrite/free radical/oxidative stress/NF-kappaB/inflammation pathway each have essential roles in AD causation.
8. 12 different occupational exposure studies have each shown that people in occupations causing them to be exposed to substantial EMF exposures have a higher AD prevalence.
9. Very young people exposed to many hours per day of EMF exposures from Wi-Fi or cell phone usage develop digital dementia.
10. There has been a decrease in the age of onset of AD in humans over the past 20 years or so, which has been suggested to be caused by increases in human EMF exposures.
11. Studies reviewed by Tolgskaya and Gordon [60] showed that rodents develop over a period of months widespread neurodegeneration from low intensity microwave frequency EMF exposures which impact many regions of the brain including the cerebral cortex and hippocampus, regions that are heavily impacted in human AD patients. This EMF caused rodent neurodegeneration resembles human neurodegeneration in having high levels of brain cell death, changes in the structure brain synapses and massive loss of synaptic connection.
12. The El-Swefy et al. [61] study showed that very low intensity mobile phone base station radiation produced massive widespread neurodegeneration in 4 weeks. 11 measured changes and 4 observed changes in this EMF-caused neurodegenerative process were each greatly lowered by the VGCC blocker amlodipine. Among the changes documented were loss of approximately 34% of the brain cells, oxidative stress, high levels of apoptosis and inflammation. Excessive [Ca2+]i acts via excessive calcium signaling and the peroxynitrite pathway of ac- tion to produce each of the 11 measured changes neurodegenerative changes.
13. While many of the studies on EMFs causing neurodegeneration in rodents did not measure any specific correlates of AD, four studies on EMFs causing AD in rats did measure such specific correlates. Two of these were discussed in detail [86, 87].
14. A series of nanosecond EMF pulses given to two-month old rats produced universal of near universal very early onset AD [78].
15. When these same pulses were started at 2 months of age and continued each subsequent day, universal or near universal AD was seen eight months after the first day of pulsation – that is in 8 month old rats [79]. Some signs of AD are seen after only four months after the beginning of irradiation. Because rats typically live to be 36 months old, these EMF pulses are causing universal or near universal very very very early onset AD. The El-Swefy et al. [61] findings are even worse – there irradiation started in 4 to 5 month old rats and massive neurodegeneration was evident after only 28 days of irradiation.
16. If humans were to succumb to very, very, very early onset AD at a similar fraction of the human life span as these rats do from EMF exposure [79], then we might expect humans to come down with EMF-caused AD at roughly 21 years of age.
17. The rat studies of EMF causation of AD [78, 79] clearly show that EMFs lower the latency period of AD and epidemiological studies suggest this is also true in humans.
18. The very early AD onset found in a study [78] and the very very very early onset AD or other neurodegeneration found in a few studies [61, 79] should be viewed as remarkable in another context. Up until 30 years ago, early onset AD in humans was caused mainly by relatively rare mutations that each have powerful causal roles in AD [23]. However, we see here universal or near universal very or very, very, very early onset AD being caused solely by EMF pulses.
These eighteen findings provide a specific type of evidence arguing that EMFs cause AD, possibly including very very very early onset AD in humans. These must be interpreted in conjunction with two other important findings:
Electronically generated EMFs are coherent, being emitted at a specific frequency, in a specific direction with a specific polarity and phase and for that reason, they generate vastly higher electrical forces and time varying magnetic forces than natural incoherent EMFs [22]. Those time varying magnetic forces are very highly penetrating and can act both directly and indirectly to place strong forces on the electrical charges on the VGCC voltage sensor to activate the channels [22]. They can, therefore, produce very highly penetrating effects deep in the human body even when they are present at millimeter wave frequencies where electric fields are largely absorbed in the outer 1 mm or so of the body. Five studies cited in another study [22] showed that non-pulsed MM-waves produced EEG changes in the human brain, with four of them also showing other neurological effects in the human brain, confirming the presence of penetrating effects.
Pulsations, both modulating pulses and pure nanosecond pulses produce much higher effects than non-pulsed EMFs of the same average intensity. Moreover, the entire telecommunications industry is in a big push towards greater and greater pulsation in order to carry larger and larger amounts of information. This includes, of course, 2G leading to 3G leading to 4G leading to 5G and, in addition, smart meters, smart cities and even smart highways, etc. This push for smarter, ever more highly pulsed devices may well be leading us to the ultimate disaster: universal or near universal very very very onset AD in human populations. Both animal and human studies, discussed above, show that EMFs can not only greatly increase the incidence of AD but can also decrease the latency period; the human latency of AD may decrease from about 25 years to perhaps 5 or 10 years. This means that it is possible that exposures we already have, 5G and possibly also 4G and smart meters, may have already caused the ultimate disaster, but we do not know it yet because we are still in the latency period.
The confluence of these changes of our understanding of EMFs put us at great risk of producing this ultimate disaster in the light of the 19 different findings regarding EMFs and AD listed above: the coherence of electronically generated EMFs, which produce vastly greater electrical and time varying magnetic forces than do natural incoherent EMFs [22]; the high level sensitivity of the voltage sensor controlling the VGCCs and other voltage gated ion channels to those forces; the importance of pulsation; and the push to faster and faster modulating pulsation in order to carry ever more information together put us at unprecedented risk.
Electronically generated electromagnetic fields (EMFs), including those used in wireless communication such as cell phones, Wi-Fi and smart meters, are coherent, producing very high electric and magnetic forces, which act on the voltage sensor of ...
