Nuclear Medicine imaging and Theranostics

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Nuclear Medicine imaging and Theranostics Discover Nuclear Medicine Imaging & Theranostics: From advanced scans to life-saving therapies.

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08/11/2025

Pre and post therapy PET MIP IMAGES

Pre and post therapy PET MIP IMAGES Nuclear Medicine imaging and Theranostics
08/11/2025

Pre and post therapy PET MIP IMAGES
Nuclear Medicine imaging and Theranostics

Neurology PET SCAN to rule out various dementia’s.Nuclear Medicine imaging and Theranostics
08/11/2025

Neurology PET SCAN to rule out various dementia’s.

Nuclear Medicine imaging and Theranostics

Bone metastasis.Functional changes(in PET) appear before anatomical changes(in CT) in tissue.Nuclear Medicine imaging an...
07/11/2025

Bone metastasis.

Functional changes(in PET) appear before anatomical changes(in CT) in tissue.

Nuclear Medicine imaging and Theranostics

Package types
07/11/2025

Package types

Stochastic vs. Deterministic Effects — What Radiation Really Does!Understanding radiation effects isn’t just physics…It’...
07/11/2025

Stochastic vs. Deterministic Effects — What Radiation Really Does!
Understanding radiation effects isn’t just physics…
It’s the foundation of radiation safety in Nuclear Medicine.

✅ Stochastic Effects
“Chance-based effects — no threshold.”
Even small doses can cause them, but probability increases with dose.

• Caused by random DNA mutations
• Severity does NOT depend on dose
• Only the probability increases
• Examples: Cancer induction, genetic mutations

In Nuclear Medicine:
These effects guide our principle of ALARA — keeping dose “As Low As Reasonably Achievable”.

✅ Deterministic Effects
“Threshold effects — dose must cross a limit.”
Below the threshold → No effect
Above the threshold → Effect appears and severity increases.

• Caused by cell death in large numbers
• Severity increases with dose
• Examples: Skin erythema, cataracts, sterility, ARS (Acute Radiation Syndrome)

In Nuclear Medicine:
Deterministic effects are rare due to low doses — but critical in therapy doses, spills, and contamination events.

Quick Memory Hack:
Stochastic = “Maybe happens”
Deterministic = “Will happen after a threshold”
fansNuclear Medicine imaging and TheranosticsDlamini Hlubi LomuhleKareem KhanMoiz Ud DinVivek PaudyalYusuf Ibrahim Safana

06/11/2025

Case of unknown primary with bone metastasis.
met

Your Body Glows… Even When You Don’t Know It!The Human Body Naturally Emits RadiationYes — even without any scan, your b...
06/11/2025

Your Body Glows… Even When You Don’t Know It!
The Human Body Naturally Emits Radiation

Yes — even without any scan, your body is radioactive.

✅ Potassium-40 (K-40) inside your muscles gives off tiny gamma rays
✅ You emit about 4,000 decays per second
✅ This natural radiation is what PET & SPECT scanners are designed to see on a larger scale

If your body didn’t have natural radioactivity, full-body PET scanners would need recalibration!

Ischemia vs. Infarct — The Difference Your Scan Can See!Ischemia = “Struggling Heart Muscle”Blood flow is reduced but no...
06/11/2025

Ischemia vs. Infarct — The Difference Your Scan Can See!

Ischemia = “Struggling Heart Muscle”
Blood flow is reduced but not completely blocked.
The tissue is still alive, still salvageable — but signalling distress.

Infarct = “Dead Heart Muscle”
Blood flow has been completely cut off for too long.
Muscle becomes non-viable and cannot recover.

⸻

How Nuclear Medicine Differentiates Them

Ischemia = Reversible Defect
• Normal uptake at rest
• Reduced uptake during stress
→ Indicates treatable disease (angioplasty/stent may help).

Infarct = Fixed Defect
• No uptake in both rest & stress
→ Indicates permanent damage (scar).

Why This Matters Clinically

• Helps cardiologists decide who needs a stent
• Predicts viability and potential recovery
• Prevents unnecessary invasive procedures
• Guides management in chronic coronary artery disease
Dlamini Hlubi LomuhleKareem KhanMoiz Ud DinVivek PaudyalYusuf Ibrahim Safanaايمن حمادJoana RosasIoana CatalinaAlexandre Alves Firmino

Pregnancy and radioiodine therapy Nuclear Medicine imaging and Theranostics
05/11/2025

Pregnancy and radioiodine therapy

Nuclear Medicine imaging and Theranostics

Running for the Heart — The Science of Physical Stress TestingWhen we make patients walk or run on a treadmill during a ...
05/11/2025

Running for the Heart — The Science of Physical Stress Testing

When we make patients walk or run on a treadmill during a cardiac scan, we’re not just testing stamina — we’re testing the heart’s true performance under pressure.

Physical Stress Test helps reveal hidden ischemia — the areas where blood flow fails to meet demand when the heart is working hard.

How it works:
•The patient exercises on a treadmill (or cycle) while ECG, blood pressure, and symptoms are monitored.
•Once the target heart rate is achieved, a radiotracer (like ⁹⁹ᵐTc-sestamibi) is injected.
•Myocardial perfusion imaging (MPI) then captures how well different regions of the heart are being perfused.

What it tells us:
•Normal perfusion = healthy coronary arteries
•Reduced perfusion = possible blockage

Sometimes, the heart’s silence during rest speaks only when it’s under stress.


fansDlamini Hlubi Lomuhle

Skin damages induced by radiation.Nuclear Medicine imaging and Theranostics
05/11/2025

Skin damages induced by radiation.

Nuclear Medicine imaging and Theranostics

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