19/10/2025
🧠 Scientists reversed Alzheimer’s symptoms using nanoparticles that cleared brain plaque and restored memory!
In a stunning medical breakthrough, researchers from Spain and China have reversed Alzheimer’s-like symptoms in mice using specially designed nanoparticles.
Published in Signal Transduction and Targeted Therapy, the study shows that just three injections of these nanoparticles reduced amyloid-beta plaque buildup in the brain by up to 60% within an hour. Even more astonishing — mice suffering from severe memory loss began behaving normally within six months.
What makes this treatment revolutionary is how it works. Instead of just removing toxic proteins, the nanoparticles repair the blood-brain barrier (BBB) — the brain’s natural defense system that gets damaged early in Alzheimer’s. By restoring the BBB and reactivating a vital protein called LRP1, the therapy allows the brain to clean itself naturally, improving blood flow, reducing inflammation, and supporting neuron recovery.
This “supramolecular drug” approach could mark a major shift in how we treat neurodegenerative diseases — focusing not just on removing damage but on reviving the brain’s own self-repair systems.
While still in the animal-testing phase, this research opens the door to new hope for millions living with Alzheimer’s and related disorders.
Source:
Battaglia, G., Tian, X., et al. (2025). Signal Transduction and Targeted Therapy. Institute for Bioengineering of Catalonia & West China Hospital, Sichuan University.
