02/11/2025
๐๐ป๐ฎ๐ฝ๐ต๐๐น๐ฎ๐ฐ๐๐ถ๐ฐ ๐ฅ๐ฒ๐ฎ๐ฐ๐๐ถ๐ผ๐ป โ ๐๐ถ๐ด๐ต-๐ฌ๐ถ๐ฒ๐น๐ฑ ๐ฆ๐๐บ๐บ๐ฎ๐ฟ๐
๐๐ฒ๐ณ๐ถ๐ป๐ถ๐๐ถ๐ผ๐ป:
โ ๏ธ Severe, life-threatening type I hypersensitivity reaction
๐งช Caused by IgE-mediated mast cell & basophil degranulation โ massive histamine release
๐๐ผ๐บ๐บ๐ผ๐ป ๐ง๐ฟ๐ถ๐ด๐ด๐ฒ๐ฟ๐:
๐ Foods โ peanuts, shellfish, eggs
๐ Drugs โ penicillin, NSAIDs, contrast media
๐ชฐ Insect stings โ bees, wasps
๐งค Latex or vaccines (rare)
๐๐น๐ถ๐ป๐ถ๐ฐ๐ฎ๐น ๐๐ฒ๐ฎ๐๐๐ฟ๐ฒ๐:
โฑ๏ธ Rapid onset (minutes after exposure)
๐ฅ Airway โ throat tightness, laryngeal edema, wheezing, stridor
โค๏ธ Cardiovascular โ hypotension, tachycardia, shock
๐ฉธ Skin โ urticaria, flushing, angioedema
๐คข GI โ vomiting, diarrhea, abdominal cramps
๐ Risk of airway obstruction or cardiovascular collapse
๐๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ ๐ ๐ฎ๐ป๐ฎ๐ด๐ฒ๐บ๐ฒ๐ป๐:
๐ Epinephrine IM (first-line, mid-thigh) โ repeat if needed
๐ง Airway support + high-flow Oโ
๐ฆ IV fluids (normal saline)
๐ Adjuncts โ antihistamines (H1/H2 blockers), corticosteroids
๐ฅ Observe โฅ4โ6 h for biphasic reactions
๐๐ฒ๐ ๐๐ฎ๐ฐ๐๐:
๐ ๐๐ฝ๐ถ๐ป๐ฒ๐ฝ๐ต๐ฟ๐ถ๐ป๐ฒ ๐๐ฎ๐๐ฒ๐ ๐น๐ถ๐๐ฒ๐ โ give it early!
โฐ Delayed administration = โ mortality
๐ Patients with prior anaphylaxis should always carry an ๐๐ฝ๐ถ๐ฃ๐ฒ๐ป
๐ก๐ฒ๐ฒ๐ฑ ๐ต๐ฒ๐น๐ฝ ๐๐ผ ๐ฃ๐ฎ๐๐ ๐๐ผ๐๐ฟ ๐จ๐ฆ๐ ๐๐?
DM: ๐จ๐ฆ๐ ๐๐ ๐๐ฒ๐น๐ฝ
Text/Call: ๐ณ๐ญ๐ฏ-๐ฏ๐ฒ๐ณ-๐ญ๐ณ๐ญ๐ณ
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