International CML Foundation

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International CML Foundation

Improving outcomes for patients with CML globally. The International CML Foundation (iCMLf) is on a mission to improve outcomes for patients with CML, globally.

Founded by a dedicated group of hematologists, we are committed to ensuring every patient with CML, no matter where they are in the world, receives the best possible care. We foster international collaboration to elevate knowledge, enhance diagnostics, and drive ground-breaking research. As a charitable foundation with a global reach, we strive to empower physicians, researchers, patients and caregivers alike, in the collective pursuit of a cure. Join us and contribute to a world where a cure for CML is not just a hope, but a reality.

28/02/2026

A strong start to the iCMLf Climb for a Cure 2026 weekend.

On Friday, the iCMLf Forum “CML without borders – a dialogue from the Andes” brought together close to 70 participants, including members of the Ecuadorian CML Working Group, for a full day of case discussion, laboratory exchange, and forward-looking clinical dialogue.

From essential diagnostic testing and mutation analysis to national collaboration and CML management in 2026, the programme reflected what global partnership in practice truly looks like: international faculty working side by side with local hematologists and laboratory teams.

As our climbers prepare for the ascent, this is exactly what the Climb for a Cure represents - not only challenge and solidarity, but sustained investment in education, collaboration, and capacity-building across borders.

A great beginning, in every sense.

Thanks to Novartis for their support of the meeting.

26/02/2026

We're thrilled to welcome Ascentage Pharma as a supporting partner for the iCMLf Climb for a Cure 2026 in Ecuador.

Reaching a cure for CML takes sustained commitment from across the global community and that's exactly what partnerships like this represent. Ascentage's support helps us connect researchers, support physicians, and drive collaborative science that gives patients everywhere a better chance at a longer, healthier life.

Together, we climb and together we move closer to a world where every person with CML, regardless of where they live, has access to the best possible care.

25/02/2026

And they’re off. ✈️

Our CEO Nicola is on her way to Ecuador as the iCMLf Climb for a Cure 2026 team begins to arrive from around the world.

In just a few days - on Saturday - 19 members of the global CML community will set off on an eight-day trek through Ecuador’s Avenue of the Volcanoes, climbing to more than 4,600 metres in support of improving outcomes for people living with chronic myeloid leukemia.

Physicians. Researchers. Patients. Advocates. Industry partners.
Climbing side by side.

This is more than a physical challenge. It reflects the endurance, preparation, and collaboration required to keep progress in CML moving forward - and to ensure that progress reaches patients everywhere.

We’ll be sharing updates from Ecuador throughout the week as the team prepares to begin the climb.

If you’d like to support them, donations are open here: https://buff.ly/I9nYImq

Thanks to our sponsors: Terns, Inc., Novartis, Enliven, Ascentage, SAHMRI

25/02/2026

We’re delighted to welcome Enliven Therapeutics back as a supporting partner of the iCMLf Climb for a Cure 2026.

In CML, progress has transformed outcomes, but access to that progress is not equal. Where a patient lives still determines the care they receive.

Enliven’s support for the iCMLf Climb helps us reduce this global disparity by strengthening education, collaboration, and knowledge-sharing so that best practice reaches physicians and patients everywhere. Thank you for your commitment to advancing equitable CML treatment.

21/02/2026

ONE WEEK TO GO!

After months of training and anticipation, on Saturday, February 28th, it's finally time. Our climbers will commence their ascend!

Follow along and stay tuned for updates as they take on this incredible challenge.

Support their mission: climb-for-a-cure.raiselysite.com

With thanks to our sponsors: Novartis Novartis Cancer, Terns, Enliven, Ascentage and SAHMRI

19/02/2026

We’re pleased to share that Terns Pharmaceuticals is joining the iCMLf Climb for a Cure: 2026 in Ecuador as a supporting partner.

While advances in CML treatment have dramatically improved survival and quality of life, the work is far from finished. Achieving a cure for all patients will require sustained research, global collaboration, and continued investment in innovation. Partnerships like this play a vital role in helping us push that work forward.

We thank Terns for their support and their commitment to improving outcomes for people living with CML worldwide

18/02/2026

In less than two weeks, our climbers will embark on the Avenue of the Volcanoes - an 8-day trek through one of the most spectacular landscapes in the world, all to support CML research and patient care.

Here's what awaits them:

Days 1-2: Arriving in Quito (2,850m), they'll acclimatize and explore the UNESCO-listed capital, including a visit to the Equatorial Monument at the literal middle of the world.

Days 3-4: The challenge begins at Pasochoa Volcano Reserve, trekking through Andean forests with an optional summit to 4,200m for breathtaking panoramic views.

Days 5-6: Through volcanic valleys and rivers to Cotopaxi National Park, home to wild horses, foxes, and the iconic Andean condor.

Day 7: The final ascent along the flanks of Cotopaxi, with an optional summit of Rumiñahui (4,631m) before finishing at Tambopaxi Lodge.

Day 8: Celebration and descent – a well-earned moment to reflect on the achievement!
It's demanding. It's breathtaking. And it's all for a cause that matters.

Support their journey: climb-for-a-cure.raiselysite.com

With thanks to our sponsors: Novartis Novartis Cancer, Terns, Enliven, Ascentage and SAHMRI

17/02/2026

Ramadan Mubarak to everyone observing.

We're thinking of the healthcare professionals in our global network who will be providing care while fasting this month - and of the patients navigating treatment alongside their observance.

Wishing you peace, health, and ease throughout Ramadan.

16/02/2026

Yesterday was World Childhood Cancer Day.

CML in children is rare - so rare that many paediatric haematologists will see only a handful of cases across their entire career.

For families navigating that diagnosis, "rare" offers no comfort. They need their child's doctor to have access to the best possible expertise.

This is exactly why the iCMLf exists.

Our global network connects clinicians across continents - so a doctor treating their first paediatric CML case in Lagos or La Paz can draw on expertise from colleagues who've treated dozens.

Case discussions happen in real time. Questions get answered. Uncertainty gives way to informed confidence.

Because no child's outcome should depend on where they were born.

13/02/2026

The iCMLf is inviting collaborators to join the iCMLf Cure Consortium (iC3) - a global initiative focused on achieving a cure for CML.

TKIs transformed CML, but cure remains elusive. Nearly half of patients relapse after stopping therapy, and lifelong treatment is not sustainable everywhere.

The iC3 brings together clinicians, scientists, computational experts, and patient advocates worldwide to advance biomarker validation, immune and microenvironment research, and clinical translation toward durable treatment-free remission.

Interested in collaborating?
Contact 📩 info@cml-foundation.org to request the iC3 Prospectus and Expression of Interest form.

12/02/2026

Meet Ines.

She is gearing up to tackle the Avenue of Volcanoes Challenge in Ecuador at the end of this month!

For Ines, this climb is about expanding iCMLf's reach and building a broad community of supporters for CML patients worldwide.

She shares: "I'm excited to be supporting a comprehensive information platform for people struggling with CML as patients or caregivers. Fundraising for iCMLf is about ensuring better access to CML treatments, knowledge training, and collaboration now and in the future."

Support Ines's mission: climb-for-a-cure.raiselysite.com

With thanks to our sponsors: Novartis Novartis Cancer, Terns, Enliven, Ascentage and SAHMRI

10/02/2026

Meet Anne! She is climbing with Team Incyte (Eka, Ines, Ela and Anne) as they take on Ecuador's Avenue of Volcanoes together.

This will be Anne's third Climb for a Cure for CML. As someone who was cured of cancer, she climbs to help give that same chance to others.

Anne shares: "As someone who was lucky enough to get a curable cancer, who received the best care and who was cured, I climb with the aim to give that to others. CML is a chronic cancer requiring life long treatment, with all the side effects, tests and doctors visits that go with that.”
Support her journey and help us advance CML research and care worldwide: climb-for-a-cure.raiselysite.com

With thanks to our sponsors: Novartis Novartis Cancer, Terns, Enliven, Ascentage and SAHMRI

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