Niche Science & Technology Ltd

Niche Science & Technology Ltd Visit us at www.niche.org.uk. We are eager to provide a comprehensive clinical research service and share best practice on how we do it.

Niche Science & Technology Ltd has provided a comprehensive clinical research service to a growing number of pharmaceutical clients since its inception in 1998. Specialising in medical writing and clinical project management, we are experts at ensuring our clients successfully progress their assets through all phases of clinical development. Study Reports, CSR’s, CTA’s/IND’s, IMPD's, Clinical Study Management, Study Protocols, Ethics Submissions, Investigator Brochures, TMF management, CTDs/Submissions, Manuscripts/Journal Submissions,Data Management and Stats Analysis, Marketing Projects, Product Positioning, Training Packages, SOP’s, Communications Strategies.

Fireworks are the perfect mix of chemistry and chaos — dazzling, deafening, and just dangerous enough to make your heart...
05/11/2025

Fireworks are the perfect mix of chemistry and chaos — dazzling, deafening, and just dangerous enough to make your heart race. We love the light and the noise, but behind every burst of colour lies a little combustion science… and a fair amount of clinical fallout.

From scorched fingers to singed lungs, fireworks are medicine’s annual reminder that beauty often comes with a burn. Here’s les of a look at the bright side of celebration — and more on the darker side of what happens next.

On Bonfire Night, the 4th of July, and Diwali we set off rockets, incendiaries and explosives for our collective amusement. I am no different from everyone else in being transfixed by pyrotechnics, the smell, the noise and the thrill of watching the sky come alight [1][2].

🎃 Fright Here, Fright Now: When Modern Work Becomes the MonsterAs Halloween creeps closer, I usually take a light-hearte...
05/11/2025

🎃 Fright Here, Fright Now: When Modern Work Becomes the Monster

As Halloween creeps closer, I usually take a light-hearted look at the darker side of science — where psychology meets productivity, and fear wears a lab coat. But this year, the real ghosts don’t rattle chains… they ping notifications.

In 2025, fear hums in our data, our deadlines, and our devices. The modern workplace isn’t haunted by things that go bump in the night — it’s haunted by overload, overwhelm, and always-on expectations.

In my latest piece, “Fright Here, Fright Now,” I explore how our fear of falling behind has become the new workplace monster — and how thoughtful delegation, outsourcing, and human–AI collaboration can help exorcise it. 👻

If “right here, right now” sometimes feels more like “fright here, fright now,” this one’s for you.

At this time of year, I usually post a few light-hearted reflections on the darker side of science – a tradition that has taken me from horrifying healthcare to monstrous publishers and to metathesiophobia (the fear of change) [1][2][3]. While ghosts and ghouls still have their place.

Artificial Intelligence isn’t just changing how we discover and develop medicines — it’s redefining how we buy, contract...
05/11/2025

Artificial Intelligence isn’t just changing how we discover and develop medicines — it’s redefining how we buy, contract, and collaborate.
As sponsor contract managers navigate a rapidly shifting world of digital transformation, the challenge isn’t just about whether to adopt AI, but how to do so responsibly, efficiently, and with clear commercial value.
That’s why the upcoming PCMG Symposium on Artificial Intelligence in the Pharmaceutical Industry — held at theRoyal Society of Medicine, London, on 24th November 2025 — will bring together thought leaders, innovators, and practitioners to explore the real-world implications of AI for outsourcing and contracting.
Here, I look ahead to how world leaders at our landmark event might address the key questions facing sponsor contract managers:

· How can AI improve sourcing strategy and vendor selection?
· What are the legal, ethical, and compliance considerations?
· How do we ensure transparency and trust in assisted decision making?

🔗 Read my article here.

📅 Register for the symposium to be part of this vital discussion shaping the future of pharma partnerships: https://lnkd.in/gSvkbdBV



https://www.linkedin.com/pulse/ai-mirage-pharmas-costly-fascination-tim-hardman-guhic/

This link will take you to a page that’s not on LinkedIn

In an era when populist leaders trade in bluster over principle, the ancient voice of Marcus Tullius Cicero still cuts s...
05/11/2025

In an era when populist leaders trade in bluster over principle, the ancient voice of Marcus Tullius Cicero still cuts sharply through the noise, reminding us that courage, eloquence, and steadfast devotion to the republic remain timeless defences against the erosion of liberty.

It’s generally acknowledged that one shouldn’t comment about politics on Linked In, but discussing history is acceptable. And we can all learn from the past (if we don’t we are doomed to repeat our mistakes).

Ah, the infamous ‘five-minute task’—that innocent little to-do that strolls into your schedule wearing a smile, only to ...
05/11/2025

Ah, the infamous ‘five-minute task’—that innocent little to-do that strolls into your schedule wearing a smile, only to unpack chaos, derail your budgets, and leave your productivity in ruins by lunch.

Despite years of experience, I still fall into the same trap as professionals everywhere – that is consistently misjudging how long a task will take. This common ‘miscalculation,’ termed the planning fallacy, refers to the systematic tendency to underestimate task completion times, even when i...

I hadn’t planned to write an article this week—I was simply reorganising my files (see picture) after a stretch of writi...
05/11/2025

I hadn’t planned to write an article this week—I was simply reorganising my files (see picture) after a stretch of writing and posting on Linked In—but somewhere between sifting through 20-year old documents, renaming folders and rediscovering drafts, this article quietly wrote itself.

The way I have stored and accessed data over the past 40 years has changed markedly. In the 1980s, I mostly managed ‘information’ in the form of numbered photocopies of book chapters and journal articles that I indexed in a small brown book (I still have it somewhere).

Awkward silences speak volumes, often revealing more than words ever could. Moments of stillness can feel uncomfortable,...
05/11/2025

Awkward silences speak volumes, often revealing more than words ever could. Moments of stillness can feel uncomfortable, even unbearable, precisely because they expose the emotional undercurrents we often try to hide—uncertainty, tension, vulnerability, or disconnection.

When conversation halts, it creates a vacuum that forces both participants to confront what’s unsaid: the unspoken questions, lingering doubts, or emotional distance.

A terror as disabling as the prospect of public speaking stalks my conversations. Those moments where the flow of dialogue falters exerts an overwhelming pressure to "keep the conversation moving.

I enjoyed attending a couple of conferences over the last few weeks and it brought home how meaningful conversations go ...
05/11/2025

I enjoyed attending a couple of conferences over the last few weeks and it brought home how meaningful conversations go beyond words—they build trust, reveal insight, and deepen human connection. Offering a simple prayer that I can always foster authenticity, listen with intent, and create space for dialogue that truly matters. How about you?

We are innately social in nature, bound by a history of cooperation, storytelling, and shared understanding. The art of conversation — a complex interplay of verbal and non-verbal cues, empathy, cognitive processing, and cultural context has been central.

In an increasingly visual and emotionally driven world shaped by right-brain modes of communication, navigating this psy...
05/11/2025

In an increasingly visual and emotionally driven world shaped by right-brain modes of communication, navigating this psychosocial shift requires not just adaptability, but a deliberate cultivation of visual intelligence, emotional literacy, and critical thinking to thrive amidst fast-paced, symbol-rich, and often AI-mediated environments. Are you ready?

“The Ascent of Man,” a 1970s BBC television series, was one of the first science programmes I remember watching. The programme introduced me to the widely supported Savannah Hypothesis, whereby visual activity was critical to survival for early hominins adapting to life on the open African Savan...

In a world of constant change and endless distractions, routines offer a powerful anchor. Far from being mundane, they p...
05/11/2025

In a world of constant change and endless distractions, routines offer a powerful anchor. Far from being mundane, they provide structure, reduce decision fatigue, and create the foundation for sustained success—both personally and professionally. This is an argument that I repeatedly had with my dad when I was younger. Ah, the wisdom that comes with age - sorry dad.

In a world saturated with constant demands, information overload, and competing priorities, routine tasks can often seem mundane and uninspiring. Yet, the humble routine may be one of the most powerful and underappreciated tools for enhancing productivity, combating cognitive overload, and fostering

Is it me? Every time I open LinkedIn I’m assaulted by a tidal wave of generic ‘inspirational’ posts, vague leadership ad...
05/11/2025

Is it me? Every time I open LinkedIn I’m assaulted by a tidal wave of generic ‘inspirational’ posts, vague leadership advice, and AI-generated nonsense masquerading as thought leadership. Has social media become a landfill for half-baked content?

Throughout history, we have told stories—from cave paintings, through clay tablets to the printing press. The Renaissance launched the Golden Age of literature: Shakespeare, Dickens and JK Rowling.

The common belief in our ability to effectively multitask is largely a myth, with most people significantly overestimati...
05/11/2025

The common belief in our ability to effectively multitask is largely a myth, with most people significantly overestimating their capacity to juggle multiple cognitive tasks simultaneously.

While a tiny fraction of individuals, often called 'supertaskers,' might manage concurrent tasks without noticeable loss, this ability is exceptionally rare and not the norm. For the vast majority, attempting to split attention across demanding activities leads directly to measurable declines in performance accuracy, increased stress levels, and a higher rate of errors.

In today’s relentlessly connected and competitive work environments, multitasking is often worn as a badge of honour. From pharmaceutical regulatory strategists juggling submission deadlines to executives navigating back-to-back video calls, many professionals in our industry equate the ability to...

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