Research & Innovation - NHS ULHT

29/10/2025

Come and see us for outside the Chapel at Lincoln County Hospital.
We have Stroke ACPs here to chat to as well as members of the research team to tell you about Stroke Care at Lincoln as well as the studies we’re doing here to improve treatment and outcomes for those affected.

28/10/2025

The MOSAICC trial has just surpasssed 1,000 participants nationally and keeps on going!
Here at Lincoln, we’re consistently one of the top recruiters to this study, despite not being one of the larger ICU centres involved.
A huge well done to everyone involved. The trial centre themselves say: “Thank you for all your hard work and everything that you do!” Hear hear to that!!

24/10/2025

A great day at the ABBRUPT stakeholder event in Birmingham.
ABBRUPT is an emergency care trial comparing two treatments (Amiodarone vs Beta Blockade) for patients with new onset atrial fibrillation (NOAF) and is taking place in ICU at LCH. An informative day, discussing the importance of including all members of the MDT in trial recruitment and delivery, ACCPs and their role in clinical trials, top tips from other sites, plus great to hear from the PPI group actively involved as co-applicants on the trial. Brilliant that 2 of our ACCPs, Melissa & Kayleigh were able to join our research nurse Kelly, to give our feedback and input to the future of this important trial. Was also great to meet the trial centre team, and connect with other site teams about this important trial.

https://www.birmingham.ac.uk/research/bctu/trials/portfolio-v/abbrupt

24/10/2025

https://forms.office.com/e/10WTUp2Vr1

20/10/2025

“I wish I took part sooner” - well worth a read.

Exclusive: Gulliver Waite signed up after antidepressants and talking therapies failed to alleviate clinical depression

10/10/2025

Congratulations to Research Nurse Kelly Hubbard and Advanced Critical Care Practitioner Heather Baker for all their hard work to date on the MOSAICC study which reached 1,000 Patients Nationally this week.

A huge well done to all the team on ICU for all their amazing contributions so far to the study, which looks at the clinical effectiveness and cost of Sodium Bicarbonate in metabolically acidotic patients with Acute Kidney Injury.
Despite being one of the smaller ICUs recruiting to MOSAICC, Lincoln has consistently been a top recruiter to the study thanks to the proactive engagement of all ICU staff and the enthusiastic leadership of Kelly and Heather. Amazing work folks! The study is still open and they’ve been busy including another patient this week!

30/09/2025

National Survey on Health Services for Vulnerable Migrants in UK Emergency Departments

St George’s Emergency Department (ED) Collaborative Research Group are conducting a national survey to explore healthcare services for vulnerable migrants in UK emergency care settings. This research seeks to better understand the services available, the experiences of clinicians delivering care to this population, and ways to improve access and quality of care. We warmly invite you to share your insights by completing an online survey. Your contribution is invaluable to shaping improvements in healthcare for vulnerable migrants in UK emergency care settings.

Key Details:
• For clinical leads, managers, and frontline clinicians working in EDs or other emergency care settings
• The survey takes approximately 10–30 minutes to complete
• Participation is voluntary, and all responses are anonymised
• The deadline to participate is the 14th of December 2025

Click here to access the survey:
https://forms.office.com/Pages/ResponsePage.aspx?id=aypLDNEO2UmTmBBDhdh6-C97Aj-9OjFJlHzMDP5XbTVURjMxTFFXTURPWFBOQjhUUVBBM0JUM1hZMy4u



Thank you for supporting this important research. If you have any questions, please contact natasha.matthews@stgeorges.nhs.uk.

29/09/2025

Shared on behalf of Dr Harrison Duell, University Hospital Southampton NHS Foundation Trust

“We hope this message finds you well. We are looking to recruit Resident Doctors to our national survey related to the prescription of continuous subcutaneous infusions (‘syringe drivers’) during end-of-life care.

About the Study
This research survey aims to assess the confidence and knowledge of resident doctors working within the UK when prescribing continuous subcutaneous infusions (otherwise known as syringe drivers) during end-of-life care.
This research is being conducted to see if further undergraduate and postgraduate education is required on the topic, and what factors impact confidence and knowledge on syringe driver prescribing.

Who is Eligible to Participate?
You are eligible to take part if you:
· Have undertaken employment as a doctor within the United Kingdom during the past 12 months.
· Have full or provisional general medical council (GMC) registration as a doctor.
· During the above period you worked within a clinical training role (e.g. F1, IMT, HST), as a locally employed doctor (e.g. Trust grade doctor), or as a “locum doctor”.
We are not surveying GPs, Consultants, or SAS doctors as part of this survey.

Optional Prize Draw
Participants will have the option to enter a prize draw for a chance to win one of ten £25 vouchers.

What Will Participation Involve?
Participants will be asked to complete a short online survey (~10 minutes) about their experience prescribing syringe drivers. We will validate your identity as a doctor by collecting a small amount of personal information, which will be deleted once your identity has been confirmed.

Survey Link
If you would like to take part, please follow this link to view more information about the national research survey:
https://southampton.qualtrics.com/jfe/form/SV_9tOBslkpNfaMotw
Thank you for supporting this research. Your contribution is greatly valued.

Contact Information
For more information, please contact:
Dr Harrison Duell - harrison.duell@nhs.net
Sponsor: University Hospital Southampton NHS Foundation Trust

12/08/2025

We are proud to announce the first patient has been recruited into the MK3543-007 commercial study at Pilgrim. They are currently in the screening phase and expected to commence treatment by the end of August. The Phase 3, Randomized, Double-blind, Active-Comparator-Controlled Clinical Study to Evaluate the Efficacy and Safety of Bomedemstat (MK-3543) versus Hydroxyurea in Cytoreductive Therapy Naïve Essential Thrombocythemia Participants.

Patients are randomised to receive the investigational medicinal product (IMP), Bomedemstat, or the standard treatment, Hydroxyurea, alongside a placebo in order to show improved platelet control and symptoms of fatigue as a long-term therapeutic strategy. This study is led by Professor Ciro Rinaldi and the Haematology Research Team.

11/08/2025

The Sono-breech study is now OPEN within the Trust.
If you or your patients are between 35 and 36+6 weeks pregnant and have a scan booked, get in touch with your midwife or our Child and Family Health Research Team (Contact Amanda Mumby-Croft or Kinga Szymiczek) to find out more or take part.

07/08/2025

Congratulations to the RASPER study team for randomising 2 patients today!
RASPER opened at Lincoln on the 23rd of June and this is our third recruit already. Amazing work by Kate Parrott, the Pleural ACP team and Research Nurse Kelly Hubbard

04/08/2025

Good morning,

Lincolnshire ICB are delighted to offer another opportunity for Lincolnshire’s NHS colleagues to attend face to face NIHR Research Delivery Network PI (Principal Investigator) Essentials training. A Principal Investigator is the person responsible for ensuring the delivery and conduct of a research study at a site.

This training is for interested colleagues that are likely to be in a position to be a Principal Investigator within the next 12-18 months.

Please note, you will need to have registered for an account with NIHR Learn and have completed the Good Clinical Practice (GCP) e-learning or refresher Good Clinical Practice (GCP) | NIHR before attending.

Please email licb.lincsrihub@nhs.net to reserve your place.