25/03/2026
Around half of people who start GLP-1 medications stop within 12 months.
Given how effective these medications can be, it’s striking that many discontinue within the first year. The irony? They’re designed for long-term use, yet staying on them is often the biggest challenge.
The reasons are complex — from side effects and cost to access and practical realities of long-term treatment
But studies show something important:
➡️ If you’re not proactive, weight regain is the rule, not the exception.
This isn’t about willpower.
Weight loss triggers powerful biological defences — adaptive thermogenesis, changes in hunger hormones, and shifts in weight set-point regulation — all designed to pull weight back up.
Understanding this changes the conversation.
It’s not about trying harder.
✅ It’s about building strategies that support your new physiology long term.
For more on holistic weight management, pre-order my new book Life After Weight Loss Medications.
Link in bio. 👆🏽✨