Diploma in Infection Prevention & Control

07/12/2025

Mucormycosis is a serious opportunistic infection linked to the Mucorales fungi, impacting various organ systems, emphasizing the urgent need for awareness and improved infection control practices.

This article discusses a case of gastrointestinal mucormycosis arising within the context of colonic pseudo-obstruction. Mucormycosis, though rare, poses a significant threat, particularly in immunocompromised patients. The discussion highlights the clinical complexities associated with diagnosing and managing this condition, including symptoms, risk factors such as diabetes and malignancy, and effective treatment strategies. The need for heightened vigilance among healthcare professionals, particularly in infection prevention and control, is stressed, recognizing the evolving challenges posed by such invasive fungal infections in both hospital and community settings.

For more information and in-depth analysis, please visit www.onehealthupdate.com. https://go.upcontent.com/ab03c145-c89d-4e4b-b1a6-14f1d1b18867

06/12/2025

Wockhardt's novel antibiotic Zaynich has made history as the first New Drug Application (NDA) from an Indian company accepted by the US FDA, marking a milestone in the fight against antimicrobial resistance.

The acceptance signifies a pivotal moment for Wockhardt and the Indian pharmaceutical landscape. As global health grapples with increasing challenges posed by antimicrobial resistance (AMR) due to inadequate efficacy of existing antibiotics, Zaynich emerges as a prospective solution. The antibiotic, designated as first-in-class, shows promising activity against resistant Gram-negative bacteria, which are notorious for causing serious infections and prolonged hospital stays. The US FDA's decision to grant Zaynich a ‘fast track’ designation underscores its potential to meet urgent healthcare needs. Wockhardt highlights that the NDA filing, made on September 30, 2025, reflects a considerable achievement in stringent clinical evaluation and regulatory compliance critical to drug development.

For further insights into this significant advancement in antimicrobial therapy and its implications for both India and global health, please visit www.onehealthupdate.com. https://go.upcontent.com/0ab1b80f-6a72-4317-906a-4247ad7313b7

06/12/2025

Hospital-Acquired Infections (HAIs) remain a silent but critical challenge in India’s healthcare system. IFCAI President joins hospital leaders, infection control experts, architects, and technology innovators to explore how design and materials science can redefine safety, sustainability, and aesthetics in Indian hospitals.

Page Description Hospital Hygiene Leadership Forum

06/12/2025

Antimicrobial resistance is a pressing global health crisis, with a notable rise in resistant bacterial infections. A promising approach involves Bdellovibrio bacteriovorus, a predatory bacterium that may transform how we combat these resistant strains.

The World Health Organization's 2025 Global AMR Surveillance Report outlines that 1 in 6 bacterial infections are resistant to antibiotics, with significant mortality linked to antimicrobial resistance. Traditional antibiotic treatments face challenges in efficacy and may not be adequate for many infections, particularly in vulnerable populations. Bdellovibrio bacteriovorus offers a novel avenue, acting as a "living antibiotic" that preys on and eliminates harmful gram-negative bacteria, including those on the WHO's list of resistant pathogens. This bacterium’s multiple attack strategies may reduce the likelihood of resistance development. While there are limitations, such as its size potentially restricting deep tissue applications, safety data shows promise for its use in treating infections resistant to standard antibiotics.

Though this innovative treatment is still in its early phases, ongoing research aims to validate its effectiveness and safety for human use, with potential applications in treating chronic or multidrug-resistant infections. As the urgency surrounding antibiotic resistance rises, continued exploration of Bdellovibrio bacteriovorus could provide a game-changing tool in infection control strategies.

For further information, please visit www.onehealthupdate.com. https://go.upcontent.com/fc9ddf02-1852-4170-94a7-646851ce702d

06/12/2025

Microbiome plays a crucial role in ocular health, influencing conditions like meibomian gland dysfunction and allergic eye diseases.

The article discusses the significance of the ocular surface microbiome across various demographics, noting its relationship with conditions such as conjunctivitis and dry eye syndrome. Studies highlighted showcase how the microbiome composition can vary in newborns, children, and adults and how factors like age, gender, and specific medical conditions can influence microbial diversity on the ocular surface. Furthermore, the interplay between microbiota and local immune responses is emphasized, highlighting the potential therapeutic implications for managing ocular diseases through microbiome modulation.

For those interested in a deeper exploration of this impactful topic, please visit www.onehealthupdate.com. https://go.upcontent.com/78421a42-5d43-4f22-8af7-60e76f178251

05/12/2025

Recent trends indicate a concerning rise in obesity prevalence among US children and adolescents aged 2 to 19 years from 2011 to 2020.

An article in JAMA Pediatrics highlights the statistics, showcasing a significant increase in overweight conditions, underlining the importance of addressing this public health crisis. The discussion extends to the role of gut microbiota and early-life antibiotic exposure in obesity development, emphasizing the need for interventions focused on diet, physical activity, and behavioral changes. Multiple studies from indexed journals, including Cochrane reviews, stress the connection between antibiotic use in infancy and the subsequent risk of obesity, calling for enhanced awareness of antibiotic stewardship's long-term implications.

For those interested in a deeper dive into the associations between obesity, antibiotic exposure, and gut health, please visit www.onehealthupdate.com. https://go.upcontent.com/bbdf1631-c9cc-4351-a86e-5272342fd2e2

04/12/2025

A recent study highlights the crucial need for a One Health approach in researching zoonotic diseases, revealing a significant gap in agrifood-related zoonotic research in low- and middle-income countries.

The evidence synthesis conducted by the Juno Evidence Alliance, Newcastle University, and funded by UK International Development emphasizes that nearly half of low- and middle-income countries lack published research on zoonotic risks linked to agrifood systems. Zoonotic diseases, responsible for 2.5 billion cases of illness and millions of deaths annually, are influenced by factors such as land use, livestock production, and wildlife trade. Decision-makers often lack critical evidence to form linkages between these practices and disease emergence. The study urges for a systems-based approach to understand transmission across the food chain, encouraging international collaboration to address research gaps and ensuring effective future strategies against zoonotic spillovers.

For those interested in learning more about the factors influencing zoonotic diseases and the recommendations provided in the study, please visit www.onehealthupdate.com. https://go.upcontent.com/4404a11a-3971-4050-8560-9b53cb03672d

03/12/2025

A new library of phages, which target specific strains of Klebsiella, has been developed, shedding light on their role in gut health and diseases such as IBD and bowel cancer.

Researchers have fully characterized 52 distinct phages from five viral families, including a newly discovered group linked to the human gut. This collection highlights the importance of phages in the human microbiome, as their presence can influence gut health and disease severity. Dr. Nobrega emphasized that these phages are prevalent in healthy individuals and can predict the severity of conditions like bowel cancer and inflammatory bowel disease (IBD). Kathryn Pretzel-Shiels from Bowel Research UK noted the significance of this research in understanding the microbiome's role in bowel health. Ultimately, this phage library not only aims to improve treatment options but also enhances our understanding of phages and bacteria interactions, which is crucial in combating antibiotic resistance.

For a deeper exploration of this vital research and its implications for gut health and antibiotic resistance, please visit www.onehealthupdate.com. https://go.upcontent.com/e869633a-cfd4-4025-a166-784b04b3d572

02/12/2025

Antimicrobial resistance (AMR) remains a critical global health issue, as it threatens the effectiveness of antibiotics and complicates treatment protocols.

This article delves into the evaluation of antibiotic resistance genes in the commensal gut flora of healthy individuals, highlighting a concerning hidden reservoir for resistance transmission. The study emphasizes the role of the human microbiome in AMR, identifying that commensal bacteria can carry resistance genes, potentially leading to the spread of resistance through various pathways. Given the high prevalence of these resistance genes, the findings raise important questions regarding infection prevention and control strategies. The implications of this research underscore the need for enhanced surveillance of AMR in healthy populations to better understand and combat the growing threat of resistant infections.

For further insights and a deeper exploration of this research topic, please visit www.onehealthupdate.com. https://go.upcontent.com/bc30a7fb-8d7a-4a22-9b11-0939bf160933

01/12/2025

Antimicrobial resistance (AMR) is increasingly affecting patient treatment in ICUs, with common infections becoming difficult to manage due to antibiotic ineffectiveness, as highlighted by experts like Dr. Rommel Tickoo from Max Healthcare.

The rise in AMR is attributed to misuse and overuse of antibiotics, compelling clinicians to adapt treatment strategies. Studies indicate alarming statistics: 2.6 lakh deaths in India in 2021 were linked to infections resistant to treatment, with the elderly being particularly affected. A survey of antibiotic practices shows a concerning trend of proactive prescriptions rather than definitive treatment protocols, further complicating the issue. Experts stress the need for improved infection control, diagnostics, and targeted antibiotic use to combat this healthcare crisis effectively.

To delve deeper into this critical issue and explore strategies for combating AMR, visit www.onehealthupdate.com. https://go.upcontent.com/b0200193-0b58-467e-8e50-d0da620fd16e

30/11/2025

The Union Health Minister J.P. Nadda has launched the National Action Plan on Antimicrobial Resistance (AMR) 2.0, a strategic initiative aimed at tackling antibiotic resistance across India from 2025 to 2029.

The renewed AMR action plan seeks to address significant public health challenges posed by antimicrobial resistance, which complicates the treatment of infections and threatens critical medical procedures. It underscores the urgent need to combat the overuse and misuse of antibiotics, which have led to increased resistance among bacteria and other pathogens in hospitals, communities, and agriculture. The 2.0 plan builds on previous efforts by enhancing accountability, reinforcing the integration of human, animal, and environmental health strategies, and promoting rational antibiotic use across all healthcare levels. Furthermore, it emphasizes the development of surveillance systems, regulatory frameworks, and public awareness campaigns to foster responsible antibiotic practices.

For a deeper dive into the comprehensive strategies outlined in the AMR 2.0 initiative, visit www.onehealthupdate.com. https://go.upcontent.com/fa4c87d9-8ca5-4f74-aa52-8a76e7f5eed9

29/11/2025

Antimicrobial resistance in Rwanda has reached 30%, presenting a significant public health challenge. Overuse of medications and evolving germs complicate treatment efforts.

According to officials from the Rwanda Biomedical Centre (RBC), the growing threat of antimicrobial resistance (AMR) is primarily due to the misuse of antibiotics, leading to infection-causing germs, particularly those responsible for pneumonia, urinary tract infections, and skin infections, becoming increasingly resistant. Recently established bacteriology laboratories aim to enhance the tracking of resistance trends and assist clinicians in appropriate antibiotic prescribing. However, Dr. Noel Gahamanyi highlighted existing gaps such as insufficient research on AMR's environmental factors and limited investigation into animal-related AMR, despite over 60% of microbes affecting humans originating from animals.

Addressing these concerns requires a comprehensive One Health approach, integrating human health, veterinary, and environmental sectors to mitigate AMR's causes effectively rather than just its effects. Globally, AMR is alarmingly prevalent, with about one in six bacterial infections caused by resistant strains, particularly in urinary tract infections.

For further insights and a deeper understanding of this critical issue in Rwanda and its implications, please visit www.onehealthupdate.com. https://go.upcontent.com/2d42c40f-5e8e-45c7-a626-295e536c42c0