Dr Shambo Samrat Samajdar MD DM- Clinical Pharmacology

29/10/2025

A few more ISRPTCON 2025 memories.
Congratulations Prof Trupti Swain and Tram ISRPTCON 2025 for wonderful academic feast.
Thank you Prof Jayanta Kumar Panda for being the master of our API-ISRPT Joint symposium.
My Pronaam to my Guru Prof Santanu Tripathi sir.

29/10/2025

📢 Featured in Ei Samay Today! 📰

Happy to share my perspective in one of Bengal’s leading dailies on a landmark move in Indian healthcare policy.

🇮🇳 The 2025 amendment to India’s Drugs Rules marks a transformative leap — expanding regulatory oversight to include cell-based therapies, gene therapy products, stem cell treatments, and xenografts. These are now rightly placed alongside recombinant DNA (r-DNA) drugs under stringent review.

🌐 This brings India in sync with global giants like the FDA, EMA, PMDA, and TGA, ensuring:
✅ Rigorous licensing
✅ GMP compliance
✅ DCGI-led evaluation

🧪 As a clinical pharmacologist, I see this not just as a regulatory reform — but a bold commitment to patient safety, biotech innovation, and India’s growing role in global biopharma leadership. 🚀

🧬 The future of regenerative medicine in India just got brighter.

27/10/2025

🎙️ Honored to Speak at the 17th ISRPTCON 2025

🧠 Indian Society for Rational Pharmacotherapeutics Conference

📍 SCB Medical College, Cuttack, Odisha | 🗓️ 25–27 October 2025

It was a privilege to present on “Deprescribing in Elderly Patients with Type 2 Diabetes” — highlighting practical tools like the A–G mnemonic for safer, individualized care.

This conference was a journey back to my academic roots:

🙏 Heartfelt blessings from my MD Guide & HOD Prof. Parbaty Panda, always my guiding light. (Telephonic)
🤝 Emotional reunions with my beloved MD teachers Prof. Chaitali Pattanayak, Prof. Anju Prasad, and Prof. Ratna Palit.
🎤 Deeply humbled to have my mentor and DM Guide Prof. Santanu K Tripathi, a pioneer in deprescribing and CPRRF in India, chair my session.

Always a joy to spend time with younger brother and emerging leader Dr. Payodhi Dhar, and reconnect with brilliant minds like Dr. Subhrajyoti Bhowmick, Dr. Ruby, Dr. Subhodeep Sinha, and Dr. Jayanta Panda.

👏 Immense thanks to Prof. Trupti Swain and her entire organizing team for curating a world-class event with precision and heart.
Feeling recharged, inspired, and grateful.

23/10/2025

https://www.youtube.com/watch?v=W5b2Xk3uGOE

Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

23/10/2025

✨ Memorable Moments from ACPCON 2025, Puducherry ✨

It was a truly enriching experience to be part of ACPCON 2025, the annual conference of the Association of Clinical Pharmacologists, held in the serene and vibrant city of Puducherry this September.
I had the privilege of delivering two lectures — one on Clinical Pharmacological Reconciliation, Review and Feedback (CPRRF), and another on the timeless contributions of Dr. U. N. Brahmachari, a pioneer whose legacy continues to inspire generations of clinical pharmacologists and physicians.

Grateful to the organizers for the kind invitation and thoughtful discussions that reflected the evolving spirit of Clinical Pharmacology in India — where science, ethics, and patient care walk hand in hand. 🌿

21/10/2025

🎗 October 20 — International Mastocytosis & Mast Cell Diseases Awareness Day
On this occasion, I’m pleased to share my recent presentation on Mast Cell Disorders and Mastocytosis, delivered at the PEDALLERCON 2025 Global Allergy Summit.
🔬 Key Points Covered in the Talk:
✅ Mast cell biology & immune functions beyond allergy
✅ KIT mutations (esp. D816V) & their role in Systemic Mastocytosis
✅ Diagnostic criteria – Tryptase, CD markers, REMA score
✅ Mast Cell Activation Syndrome (MCAS) & Hereditary Alpha Tryptasemia
✅ Precision-based therapies – Midostaurin, Avapritinib, & more
✅ Case-based discussion and practical clinical pearls
📽️ Watch the full video here: [https://youtu.be/Liy5w6ZMRJk?si=HYWXo-bQEvO9QNZ9]
📣 Mast cell diseases remain underdiagnosed and often misattributed.
🔍 I invite my colleagues, clinicians, and researchers to share your thoughts, clinical experiences, or research insights on this important yet often overlooked topic.
Let’s raise the bar for awareness, diagnosis, and care.

Mast Cell Disorders and Mastocytosis represent a diverse spectrum of rare but clinically significant conditions that range from cutaneous presentations in ch...

18/10/2025

Before the first lamp of Diwali is lit, Dhanteras reminds us that true prosperity begins within. From the cosmic churning that brought forth Lord Dhanvantari — the divine healer — to the flicker of the diya that dispels our inner shadows, this festival calls us to rediscover the real Amrit: health, balance, and peace of mind.

Our article, “The Nectar of Inner Wealth,” explores how the story of Samudra Manthan mirrors our own journey — how each of us must churn through turmoil to bring forth wisdom, compassion, and healing.

💫 As we celebrate Dhanteras, may we polish not only our homes but our hearts; may the light we kindle within become the wealth that endures beyond time.

🔗 Read it on The Speaking Tree, The Times of India:
The Nectar of Inner Wealth: A Dhanteras Reflection

Daily Ecstasy News: Dhanteras, celebrating Lord Dhanvantari's emergence with the nectar of immortality and Ayurveda, reminds us that true wealth is health and peace of mi

16/10/2025

🩺 Upholding Research Integrity: Structure and Role of Ethics Committee Members

Honoured to be invited by the Indian Society for Clinical Research (ISCR) in collaboration with the Forum for Ethics Review Committees in India (FERCI) to deliver a talk at the Workshop on “Research Ethics and Good Clinical Practices” held on 15–16 October 2025.

My session focused on “Structure and Role of Ethics Committee (EC) Members” as outlined in the ICMR National Ethical Guidelines, emphasizing:

🔹 Composition & Diversity: The EC must include a balanced mix of medical, non-medical, legal, social, and lay representatives to ensure independent, multidisciplinary, and community-sensitive ethical oversight.
🔹 Roles & Responsibilities: From reviewing study protocols to safeguarding participant rights and confidentiality, EC members serve as custodians of ethical integrity in human research.
🔹 Functioning & Governance: I discussed quorum requirements, conflict of interest management, SAE reporting, and continuing review processes — critical to maintaining transparency and accountability.
🔹 Capacity Building: Strengthening EC members through ongoing training and harmonization with national/international GCP standards is central to fostering a culture of ethics in research.

As India emerges as a global leader in clinical research, the ethical framework remains our strongest foundation. Grateful to Dr. Nandini K. Kumar President FERCI for the opportunity and leadership in advancing ethical clinical research practices nationwide. Always privileged to learn from my friend Dr Saibal Das.

🧭 “Science finds its direction through ethics; progress becomes meaningful only when guided by conscience.”

15/10/2025

🌿 The Silent Guardians Within 🌿

Our article “The Silent Guardians Within: What the 2025 Nobel Prize Reveals About the Balance of Life” has been featured in The Times of India – Speaking Tree.

This year’s Nobel Prize in Physiology or Medicine celebrates Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi — whose discovery of regulatory T cells unveiled nature’s own lesson in balance. These cells remind us that true strength lies in restraint, that forgiveness is a biological truth, and that compassion sustains life as much as defense.
Our immune system, like our spirit, survives through harmony — knowing when to fight and when to forgive.
As the Upanishads say, “He who sees all beings in the Self and the Self in all beings never turns away.”

Link to read the full article:
https://timesofindia.indiatimes.com/speaking-tree/daily-ecstasy/the-silent-guardians-within-what-the-2025-nobel-prize-reveals-about-the-balance-of-life/articleshow/124575198.cms

🕊️ A tribute to the Nobel laureates — and to the divine wisdom quietly working within us all.

Daily Ecstasy News: The 2025 Nobel Prize in Physiology or Medicine recognized the discovery of regulatory T cells, the immune system's peacekeepers. These cells prevent t

14/10/2025

🌍 Honored to Present at PEDALLERCON 2025 — International Summit on Allergy Science

📍 Taj Vivanta, New Delhi | October 10–12, 2025

I had the privilege of delivering an invited lecture on "Mast Cell Disorders & Mastocytosis: From Biology to Precision Therapy" at the prestigious PEDALLERCON 2025, a global scientific conclave uniting allergy and immunology leaders from across the world.

🧬 My presentation explored:
• Mast cell biology, immune dynamics, and tissue-specific phenotypes
• KIT mutations and their role in systemic mastocytosis (SM)
• Diagnostic algorithms including REMA Score and WHO classification
• Underdiagnosed syndromes like MCAS and Hereditary Alpha Tryptasemia (HaT)
• Current and emerging therapeutic strategies: antihistamines to KIT inhibitors

This platform offered a wonderful opportunity to discuss cutting-edge advances in mast cell science and foster collaboration with global experts in allergy medicine. The academic energy and cross-border dialogue were truly inspiring.

🤝 It was a great honor to meet and interact with eminent stalwarts like
Dr. P.K. Vedanthan and Dr. Vinay Mehta from the United States.
As always, a pleasure exchanging ideas with Dr. Indranil Haldar, one of India’s most respected pulmonologists.

🙏 I remain grateful for the continued mentorship of Prof. Saibal Moitra Sir, whose guidance shapes my academic journey.

A heartfelt thank you to Dr. Neeraj Gupta for the kind invitation and for organizing such a world-class academic gathering.
Let us continue to advance awareness, diagnosis, and care in mast cell disorders, allergy, and immunology.

12/10/2025

Honoured to deliver my lecture on “Deprescribing in Elderly Diabetes Patients” at the 7th CG State Annual Conference of RSSDI, Raipur (11–12 October 2025) — a beautifully organised academic celebration themed “Beyond Monologues.”
The conference was a perfect blend of science, history, and heartfelt hospitality — every detail reflected warmth and thoughtfulness. My sincere gratitude to Dr. Raka Sheohare and his wonderful team for the impeccable arrangements and for creating the unforgettable “Diabetes ki Ram Lila” experience — a brilliant fusion of art and endocrinology! 🎭
It was an absolute pleasure spending time with Dr. N. K. Singh, whose stories always carry a rare mix of academic depth and spiritual essence. And as always, inspiring interactions with authorities like Dr. Manoj Chawla, Dr. Purvi Chawla, Dr. Rakesh Parikh, and Dr. Hridish Chakraborty made the experience even more enriching.
A heartfelt thank you to Team CG RSSDI for making Raipur 2025 truly memorable — both intellectually and emotionally. 🌸

11/10/2025

🧬 Honored to Present at PEDALLERCON 2025 – The Global Allergy Summit | New Delhi

It was a privilege to deliver a clinical session on “Mast Cell Disorders and Systemic Mastocytosis” at the 13th edition of PEDALLERCON, hosted at the Taj Vivanta, New Delhi (Oct 10–12, 2025). This global platform brought together thought leaders in allergy, asthma, and clinical immunology from across continents — a truly enriching academic experience!

🧪 My talk covered:
- Mast cell biology and immune dynamics
KIT mutations (esp. D816V) and their diagnostic implications
- WHO/ECNM classification of SM, CM, MCAS
- Diagnostic criteria including REMA score and molecular algorithms
- Precision therapeutics: from antihistamines to Avapritinib

The response from peers and delegates reaffirmed the importance of raising awareness about underdiagnosed entities like MCAS and Hereditary Alpha Tryptasemia, especially within allergy clinics.

🤝 It was an absolute honor to meet:
Dr. P.K. Vedanthan and Dr. Vinay Mehta, stalwarts in allergy medicine from the US
And always a delight to interact with Dr. Indranil Haldar, one of the most respected pulmonologists in our country.
🙏 I am forever grateful for the continued mentorship and inspiration from Prof. Saibal Moitra, whose vision continues to guide so many of us in this field.
A special thank you to Dr. Neeraj Gupta for the kind invitation and the opportunity to contribute to this landmark scientific program.
Looking forward to future collaborations in advancing allergy and immunology!