01/02/2026
Ziwig’s Endotest saliva test : aims to transform endometriosis screening, though debate remains about its clinical impact.
With diagnosis still taking an average of about 7 years and often requiring invasive procedures, a reliable noninvasive test could significantly shorten delays and reduce patient burden.
The Ziwig Endotest® is a groundbreaking, non-invasive diagnostic tool designed to detect endometriosis using a simple saliva sample ,uses Next-Generation Sequencing (NGS) and Artificial Intelligence (AI) to analyze a signature of 109 different microRNAs in saliva.
High Accuracy: sensitivity of over 97% and a specificity of over 93%.
Scope: It is designed to detect all types of endometriosis, including superficial, deep infiltrating, and ovarian endometrioma.
Sample Collection Process
The test requires a, supervised saliva collection, ideally in the morning.
Precautions: Within 30 minutes before the test, patients must not eat, drink, smoke, chew gum, wear lipstick, or brush their teeth.
Turnaround Time: Results are generally available in 3 to 4 weeks.
Status: It has obtained the CE mark for in vitro diagnostic medical devices in Europe.
The test drew attention at the 2025 Paris Women’s Health Congress, even as its relevance continues to be discussed within the scientific community.
