30/04/2021
*Family history can be used to define women who are at increased risk of ovarian cancer.*
A *_woman is defined as being at high risk of ovarian cancer if*_ she has a first-degree relative (mother,father,sister,brother,
daughter or son) affected by cancer within a family with:
● 2 or more individuals with ovarian cancer, who are first-degree relatives of each other
● 1 individual with ovarian cancer at any age and one with breast cancer diagnosed under age 50 years who are first-degree* relatives of each other
● 1 relative with ovarian cancer at any age and two with breast cancer diagnosed under age 60 years who are connected by first-degree relationships
● 3 or more family members with colon cancer, or two with colon cancer and one with stomach,
ovarian,endometrial,urinary tract or small bowel cancer in two generations.One of these cancers must be diagnosed under age 50 years and affected relatives should be first-degree relatives of each other
● 1 individual with both breast and ovarian cancer.
*Where family history is significant,referring the woman to the Regional Cancer Genetics service should be considered.*
Referrence
**The Management of Ovarian Cysts in PostmenopausalWomen
Green-top Guideline No. 34
July 2016**
