07/08/2025
过去有好几位病人找我看诊,都是年轻人,主要症状“呼吸不过来”、“胸口闷呼吸不顺”、“一直想深呼吸但吸不饱”,甚至觉得自己是不是心脏或肺出了问题。他们看起来焦虑,症状也非常真实。于是我们做了详细的检查:胸部X光、肺功能测试、CT thorax、心电图、甚至心脏专科评估,全都正常。
接着,我让他们填写了一个叫 Nijmegen问卷 的评估表,发现分数都偏高,可能是 过度换气综合征(Hyperventilation Syndrome, HVS)。这是一种呼吸功能紊乱,常常和压力或焦虑有关,症状可以和严重疾病非常相似。
我们有时会进一步安排 动脉血气分析(ABG) 来辅助判断。ABG 检查常见的结果是 呼吸性碱中毒:二氧化碳(PaCO₂)偏低、pH 值偏高,以及碳酸氢盐(HCO₃⁻)正常或稍低。这意味着患者虽然感觉“吸不到气”,其实是呼吸过快、过深,把体内的二氧化碳排出太多,导致体内酸碱平衡被打破。这种不平衡会引发头晕、手脚发麻、胸口闷等症状,加重呼吸困难的感觉,形成恶性循环。这并不是“假装不舒服”,而是一种真实存在的生理反应。
但也要注意:如果患者在检查时没有症状发作,ABG 可能会呈现正常结果,这并不代表问题不存在,而是因为症状具有间歇性.
不过也要提醒大家,包括医生们:HVS 是一个 排除性诊断,必须先排除其他器质性疾病,才可以放心下这个结论。很多时候,病人的症状也会随着时间演变,因此也需要持续观察、定期追踪,不能掉以轻心,以避免误诊.
治疗方面,呼吸训练 放松练习、认知行为疗法 或冥想等方法,能有效打破恶性循环。建议大家试试看一些免费的呼吸训练工具,例如 Nijmegen问卷(连结)、手机APP如 The Breathing App 或 Breathe2Relax,对调节呼吸节奏有帮助。
In the past, I’ve seen quite a few patients, mostly young and otherwise healthy, coming in with symptoms like “I can’t breathe properly,” “my chest feels tight,” or “I keep trying to take deep breaths, but it’s never enough.” They often appear anxious, and their symptoms are very real. So we run a thorough workup: chest X-ray, lung function tests, CT thorax, ECG, and sometimes even referral to a cardiologist and all results come back normal.
Next, I have them fill out something called the Nijmegen Questionnaire, and many of them score high. This points to the possibility of Hyperventilation Syndrome (HVS) — a functional breathing disorder commonly associated with stress or anxiety. The symptoms often resemble those of more serious diseases.
We sometimes go a step further and perform arterial blood gas (ABG) analysis to support the diagnosis. A typical finding in HVS is respiratory alkalosis: low carbon dioxide (PaCO₂), slightly elevated pH, and normal or slightly low bicarbonate (HCO₃⁻). This suggests that although the patient feels like they can’t breathe, in reality they are breathing too fast or too deeply, causing excessive CO₂ loss and disrupting the body’s acid–base balance. This imbalance can lead to dizziness, tingling, chest discomfort, and worsened breathlessness, forming a vicious cycle. This is not “imagined illness”, it is a real, measurable physiological reaction. However, it’s important to note that if the patient is not actively symptomatic during the test, the ABG may appear normal. That doesn’t mean the problem isn’t there, it just reflects the intermittent nature of the symptoms.
That said, it’s crucial for both patients and doctors to remember that HVS is a diagnosis of exclusion. Other organic diseases must be ruled out before we can confidently make this diagnosis. And since symptoms may evolve over time, patients require ongoing monitoring and regular follow-up to avoid missing a more serious underlying cause.
In terms of treatment, breathing retraining, relaxation techniques, cognitive behavioural therapy (CBT), and even mindfulness or meditation can help break the vicious cycle. I encourage patients to explore free breathing tools such as the Nijmegen Questionnaire or apps like The Breathing App and Breathe2Relax, which are great for restoring proper breathing rhythm.