09/04/2023
The endocrine system is a network of glands that produce and release hormones that help control many important body functions, including the body's ability to change calories into energy that powers cells and organs. The endocrine system influences how your heart beats, how your bones and tissues grow, even your ability to make a baby. It plays a vital role in whether or not you develop diabetes, thyroid disease, growth disorders, s*xual dysfunction, and a host of other hormone-related disorders.
Glands of the Endocrine System
Each gland of the endocrine system releases specific hormones into your bloodstream. These hormones travel through your blood to other cells and help control or coordinate many body processes.
Endocrine glands include:
Adrenal glands: Two glands that sit on top of the kidneys that release the hormone cortisol.
Hypothalamus: A part of the lower middle brain that tells the pituitary gland when to release hormones.
Ovaries: The female reproductive organs that release eggs and produce s*x hormones.
Islet cells in the pancreas: Cells in the pancreas control the release of the hormones insulin and glucagon.
Parathyroid: Four tiny glands in the neck that play a role in bone development.
Pineal gland: A gland found near the center of the brain that may be linked to sleep patterns.
Pituitary gland: A gland found at the base of brain behind the sinuses. It is often called the "master gland" because it influences many other glands, especially the thyroid. Problems with the pituitary gland can affect bone growth, a woman's menstrual cycles, and the release of breast milk.
Te**es: The male reproductive glands that produce s***m and s*x hormones.
Thymus: A gland in the upper chest that helps develop the body's immune system early in life.
Thyroid: A butterfly-shaped gland in the front of the neck that controls metabolism.
Even the slightest hiccup with the function of one or more of these glands can throw off the delicate balance of hormones in your body and lead to an endocrine disorder, or endocrine disease.
Causes of Endocrine Disorders
Endocrine disorders are typically grouped into two categories:
Endocrine disease that results when a gland produces too much or too little of an endocrine hormone, called a hormone imbalance.
Endocrine disease due to the development of lesions (such as nodules or tumors) in the endocrine system, which may or may not affect hormone levels.
The endocrine's feedback system helps control the balance of hormones in the bloodstream. If your body has too much or too little of a certain hormone, the feedback system signals the proper gland or glands to correct the problem. A hormone imbalance may occur if this feedback system has trouble keeping the right level of hormones in the bloodstream, or if your body doesn't clear them out of the bloodstream properly.
Increased or decreased levels of endocrine hormone may be caused by:
A problem with the endocrine feedback system
Disease
Failure of a gland to stimulate another gland to release hormones (for example, a problem with the hypothalamus can disrupt hormone production in the pituitary gland)
A genetic disorder, such as multiple endocrine neoplasia (MEN) or congenital hypothyroidism
Infection
Injury to an endocrine gland
Tumor of an endocrine gland
Most endocrine tumors and nodules (lumps) are noncancerous. They usually do not spread to other parts of the body. However, a tumor or nodule on the gland may interfere with the gland's hormone production.
Types of Endocrine Disorders
There are many different types of endocrine disorders. Diabetes is the most common endocrine disorder diagnosed in the U.S.
Other endocrine disorders include:
Adrenal insufficiency. The adrenal gland releases too little of the hormone cortisol and sometimes, aldosterone. Symptoms include fatigue, stomach upset, dehydration, and skin changes. Addison's disease is a type of adrenal insufficiency.
Cushing's disease. Overproduction of a pituitary gland hormone leads to an overactive adrenal gland. A similar condition called Cushing's syndrome may occur in people, particularly children, who take high doses of corticosteroid medications.
Gigantism (acromegaly) and other growth hormone problems. If the pituitary gland produces too much growth hormone, a child's bones and body parts may grow abnormally fast. If growth hormone levels are too low, a child can stop growing in height.
Hyperthyroidism. The thyroid gland produces too much thyroid hormone, leading to weight loss, fast heart rate, sweating, and nervousness. The most common cause for an overactive thyroid is an autoimmune disorder called Grave's disease.
Hypothyroidism. The thyroid gland does not produce enough thyroid hormone, leading to fatigue, constipation, dry skin, and depression. The underactive gland can cause slowed development in children. Some types of hypothyroidism are present at birth.
Hypopituitarism. The pituitary gland releases little or no hormones. It may be caused by a number of different diseases. Women with this condition may stop getting their periods.
Multiple endocrine neoplasia I and II (MEN I and MEN II). These rare, genetic conditions are passed down through families. They cause tumors of the parathyroid, adrenal, and thyroid glands, leading to overproduction of hormones.
Polycystic o***y syndrome (PCOS). Overproduction of androgens interfere with the development of eggs and their release from the female ovaries. PCOS is a leading cause of infertility.
Precocious puberty. Abnormally early puberty that occurs when glands tell the body to release s*x hormones too soon in life.
The endocrine system is a collection of glands and organs that regulate bodily processes using hormones. Hormones are chemical messengers that travel through the bloodstream to influence bodily processes.
Primary parts of the endocrine system include the:
hypothalamus
pineal body
pituitary gland
thyroid and parathyroid
thymus
adrenal gland
pancreas
ovaries
testicles
These and other parts of the endocrine system regulate a range of processes, including metabolism, reproduction, and growth.
Endocrine disorders occur when one or more parts of the system do not work correctly. This typically causes high or low levels of certain hormones or results in the body not responding correctly to certain hormones. This can lead to problems around the body.
Endocrinology refers to the study of hormones, and an endocrinologist is a doctor who specializes in hormones. These doctors can provide treatment options that can help restore the normal balance and function of the hormones in a person’s body.
Causes
Endocrine disorders have a range of different causes, depending on the condition.
For example, acromegaly and Cushing’s syndrome often result from a tumor in the adrenal or pituitary gland. These tumors are usually noncancerous but still require removal to manage the condition.
Some problems result from hormonal imbalances. For example, hyperthyroidism and hypothyroidism relate to the amount of thyroid hormones the thyroid gland produces and whether it is overactive or underactive. Also, high androgen levels in females can cause polycystic o***y syndrome (PCOS).
In some cases, an autoimmune condition causes endocrine problems. For example, type 1 diabetes is the result of the immune system destroying insulin-producing cells in the pancreas. Graves’ disease is also an autoimmune condition, and it can result in hyperthyroidism.
Common endocrine disorders
There are many different types of endocrine disorders. Some examples include the following.
Diabetes
Diabetes is a condition that causes high blood glucose levels due to the body being unable to either produce or use insulin sufficiently to regulate glucose. Two of the most common types of diabetes are type 1 and type 2.
Diabetes causes symptoms that include:
increased thirst and urination
increased hunger
unexpected weight change.
Understanding Your Health
