PHARM K.

PHARM K. Meds and Health

Epigenetics in Action: The Honeybee Story 🐝✨Epigenetics explains how gene expression can change without altering the und...
07/12/2025

Epigenetics in Action: The Honeybee Story 🐝✨

Epigenetics explains how gene expression can change without altering the underlying DNA sequence. A fascinating example comes from honeybees (Apis mellifera).

🔹 Queen and worker bees are genetically identical, yet they differ in behavior, physiology, and appearance.
🔹 The key difference? Diet.

Queen bees are fed royal jelly, while worker bees receive nectar.
Royal jelly contains compounds that inhibit the enzyme cytosine methyltransferase, which normally adds methyl groups (–CH₃) to cytosine bases on DNA.
When methylation is blocked, certain genes become active, leading to the development of a queen bee.

Scientists have even replicated this effect—worker bees given royal jelly-like conditions start developing queen-like traits.

This is epigenetics:
Changes such as DNA methylation or modifications to histone proteins that affect gene expression without changing the DNA sequence.

Other examples include:
🔸 Histone modification (methyl or phosphate groups)
🔸 X-inactivation in female mammals, where one X chromosome is randomly switched off during embryonic development.


https://www.facebook.com/100067139978126/posts/1164053289175993/
07/12/2025

https://www.facebook.com/100067139978126/posts/1164053289175993/

✅ pH Values of Human Body Fluids

pH is a measure of how acidic or alkaline a substance is. Human body fluids maintain specific pH ranges to support normal physiological functions. Even slight deviations can affect digestion, immunity, enzyme activity, and overall homeostasis.

The infographic lists major body fluids along with their normal pH ranges and biological significance. Below is an expanded and detailed explanation of each.

🔰 1. Saliva (pH 6.2 – 7.6)

Saliva is generally slightly acidic to neutral.
It helps in:
◾ Initial digestion of carbohydrates via salivary amylase
◾ Lubrication of food for swallowing
◾ Protecting oral tissues and maintaining tooth health

🔰 2. Blood (pH 7.35 – 7.45)

Blood is slightly alkaline and one of the most tightly regulated fluids in the body.
◾ Maintains acid-base balance essential for enzyme function
◾ Regulated by lungs, kidneys, and buffer systems
◾ Even minor fluctuations can be life-threatening

🔰 3. Gastric Juice (pH 1.5 – 3.5)

Gastric juice is highly acidic, mainly due to hydrochloric acid (HCl).
◾ Helps break down proteins
◾ Activates pepsin enzyme
◾ Kills harmful microorganisms entering with food

🔰 4. Urine (pH 4.5 – 8.0)

Urine pH is highly variable and reflects diet, hydration, and metabolic status.
◾ Acidic urine may indicate high protein intake or metabolic disorders
◾ Alkaline urine may occur after meals or certain infections
◾ Helps the body remove excess acids/bases

🔰 5. Tears (pH ~7.0)

Tears are generally neutral.
◾ Protect the eyes from irritants
◾ Provide lubrication and nourish corneal tissues
◾ Contain antimicrobial enzymes like lysozyme

🔰 6. Sweat (pH 4.5 – 7.0)

Sweat is usually slightly acidic and varies widely.
◾ Helps regulate body temperature
◾ Mild acidity prevents bacterial growth on the skin
◾ Contributes to skin surface pH balance

🔰 7. Bile (pH 7.6 – 8.8)

Bile is alkaline and produced by the liver, stored in the gallbladder.
◾ Essential for fat digestion and absorption
◾ Neutralizes acidic chyme from the stomach
◾ Helps in waste excretion (bilirubin, cholesterol)

🔰 8. Pancreatic Juice (pH 7.5 – 8.0)

Pancreatic juice is alkaline, rich in bicarbonate.
◾ Neutralizes stomach acid entering the duodenum
◾ Provides the ideal pH for pancreatic enzymes
◾ Facilitates digestion of fats, proteins, and carbohydrates

🔰 9. Cerebrospinal Fluid (pH 7.3 – 7.4)

CSF is slightly alkaline.
◾ Cushions and protects the brain and spinal cord
◾ Maintains a stable chemical environment for neurons
◾ Assists in nutrient transport and waste removal

🔰 10. Vaginal Fluid (pH 3.8 – 4.5)

Vaginal fluid is acidic due to lactic acid production.
◾ Prevents growth of harmful pathogens
◾ Supports healthy microbiome (Lactobacillus species)
◾ pH varies with menstrual cycle, age, and hormonal changes

🔰 11. Semen (pH 7.2 – 8.0)

Semen is slightly alkaline.
◾ Protects s***m from acidic vaginal environment
◾ Enhances s***m motility and survival
◾ Ensures successful fertilization conditions

01/12/2025
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29/11/2025

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08/11/2025

Today we honor the life and work of James Watson, co-discoverer of the double-helix structure of DNA, has passed away. H...
08/11/2025

Today we honor the life and work of James Watson, co-discoverer of the double-helix structure of DNA, has passed away. His work was a turning point in science, laying the foundation for modern genetics and transforming how we understand life at its most fundamental level. The discovery of DNA’s structure continues to drive breakthroughs in medicine, biotechnology, and evolutionary biology, a milestone that reshaped science, and the world.

🔑 Genotype testThis shows if you carry sickle cell traits (AA, AS, SS). Two people with AS or SS should avoid marrying t...
11/10/2025

🔑 Genotype test
This shows if you carry sickle cell traits (AA, AS, SS). Two people with AS or SS should avoid marrying to prevent having children with sickle cell disease.

🔑 Blood group test
Knowing your ABO and Rh type helps prevent pregnancy complications. For example, if a woman is Rh-negative and her partner Rh-positive, medical care is needed to protect future babies.

🔑 HIV test
Both partners should know their HIV status. Early detection helps with treatment and prevents transmission to each other or future children.

🔑 Hepatitis B & C tests
These viral infections can spread through s*x or contact with infected blood. Testing helps with early treatment or vaccination.

🔑 STD tests
Tests for infections like syphilis, gonorrhea, and chlamydia are important because they can cause infertility or affect unborn babies if untreated.

🔑 Fertility test
A semen analysis for men and hormone or pelvic scans for women can detect possible reproductive problems early.

🔑 Mental health check
Emotional and psychological well-being matter in marriage. It helps couples understand each other and seek help early if needed.

🔑 Blood sugar test
Checks for diabetes, which can affect fertility and overall health.

Happy weekend🥱🥰Follower
31/08/2025

Happy weekend🥱🥰
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