It is our immense pleasure to disseminate the information about Nepal National Tuberculosis Programme (NTP) in the digital platform. Tuberculosis still remains one of the major public health problem in Nepal. The Ministry of Health and Population carried out Tuberculosis Prevalence Survey (TBPS) in 2018/19 and estimated 117,000 (416/100,000 population) prevalent cases and 69,000 (245/100,000) incidence TB cases annually, which is 1.8 and 1.6 times higher than previously estimated by the WHO. The estimated TB mortality was 17,000 per year, which is 3.1 times higher than previous estimation (5,500). The Drug Resistance TB (DRTB) is emerging as challenges to fight against TB and achieve the targets of the Sustainable Development Goal by 2030 and End TB by 2050. The survey also provided new estimation on DRTB cases (2,200 annually), which is 1.57 times higher than the previously estimated.