House of Health

06/12/2025

Big News: A Major Breakthrough in Hydrogen Science
Fresh off the press this week!
​Just-released paper in Redox Biology (5-Year IF 13.1, SCImago Q1) is a milestone for the entire hydrogen field.

For years, researchers and many of you have asked fundamental questions:

How does H2 work?
What does it actually bind to?
Why do its effects last long after the gas is gone?
How does it benefit the mitochondria?
And so on…
This publication provides a major part of the answer.

Read the press release: https://molecularhydrogeninstitute.org/study-identifies-first-molecular-target-of-hydrogen/

Read the published paper here:
https://www.sciencedirect.com/science/article/pii/S2213231725004653?via%3Dihub

What the Study Found
The study discovered that exposure to molecular hydrogen targets the Rieske iron-sulfur protein (RISP), triggering its LONP1-mediated degradation RISP is a critical component of mitochondrial Complex III. Hydrogen suppresses Complex III activity within minutes, signaling the cell that something has changed. This triggers a controlled mitochondrial hormetic response, a repair-and-strengthen cycle that mitochondria naturally use to stay resilient.

The cell responds by rebuilding and upregulating RISP, restoring and even enhancing function within hours.
This mechanism neatly explains many of the “paradoxical” findings in hydrogen research why some markers go up, others go down, yet outcomes typically improve.
This is an elegant unifying mechanism, indicating hydrogen is not biologically inert but like other small biological gases (NO⋅, CO, H₂S) but with its own unique twist.

This paper:

Further moves the field beyond the old “antioxidant” narrative
Shows that hydrogen interacts with a conserved mitochondrial protein
Helps explain the diverse and long-lasting effects seen across preclinical and clinical studies
This is the kind of work that shifts an entire field forward.

A groundbreaking paper published this week in Redox Biology reveals the first clearly defined molecular target of molecular hydrogen (H₂).

06/12/2025

Molecular Hydrogen.
Its such an important gas. Link to generators for personal use in the comments.
https://www.facebook.com/share/p/1WNEQJU9Bs/

19/11/2025

Switching to a healthier way of eating isn't too hard .

It is increasing our risk of a range of chronic diseases, including obesity and depression, a major review says.

31/10/2025

Hormonal contraceptives under the spotlight.

In a nationwide Swedish study of over 2 million girls and women followed up for more than 21 million person-years, the use of hormonal contraceptives was associated with a 24% increased risk for breast cancer, with both combined and progestin-only formulations associated with increased risk. http://ms.spr.ly/6187tEdwW

31/10/2025

Users of e-cigarettes had increased odds of peptic ulcer disease compared to those who have never used them, a cross-sectional study found. http://ms.spr.ly/6185tDE5N

29/10/2025

Get out there!

23/10/2025

It might not be the gluten. But its so commonly villanised!

The findings of a landmark study have revealed that gluten sensitivity, which affects approximately 10% of the global population, is not actually about gluten but part of the way the gut and brain interact.

In the largest combined analysis, only a few tightly controlled trials found any real gluten reaction. Overall, people’s responses were no different from when they were given a placebo. This study is expected to set a new benchmark for how gluten sensitivity is defined, diagnosed and treated.

Tap through to read more → unimelb.me/3L3jDaQ

16/10/2025

Are you taking collagen, hoping it will result in improvements in wrinkles, skin elasticity and hydration? A recent analysis of the research showed that these effects were only significant among studies which had been funded by pharmaceutical companies.
My tip in the comments

Collagen supplements are promoted to help aging skin. However, no meta-analysis of randomized controlled trials (RCTs) has examined their effects by funding source and study quality, which may influence outcomes.

15/10/2025

Protein Powders and Shakes Contain High Levels of Lead
Protein supplements are wildly popular, but CR’s tests of 23 products found that more than two-thirds of them contain more lead in a single serving than our experts say is safe to have in a day.
While these brands are from the USA market it cannot be ruled out that the ones available here are any different.

CR tests of 23 popular protein powders and shakes found that most contain high levels of lead.

10/10/2025

How 20 minutes outside can reboot your hormones

Spending just 20 minutes in nature can lower blood pressure, heart rate and stress levels.

29/09/2025

Laboratory research shows dandelion root extract killed more than 90% of colon cancer cells within 48 hours, while leaving healthy cells unharmed. The extract triggered multiple cell-death pathways, even in cancers lacking the tumor-suppressor gene p53. In mice, it also slowed tumor growth without toxicity. There are numerous studies, and as must have been done in the lab and in animal models, one must consider the results preliminary and human clinical trials are still needed.
Here's one of the many studies: Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways - https://pubmed.ncbi.nlm.nih.gov/27564258/

Dandelion root helps with liver health (quadruples bile flow), helps fat metabolism, it's high in potassium, helps digestion, and it's a good coffee substitute. It helps to clear the lymph and blood of toxins as well. Great for acne, hormonal issues, constipation, brain fog, and so much more.

Best form for home preparation: Tea or Decoction

For Tea: 1-2 tbslp per cup of boiling water. Brew 10-15 mins

For Decoction: Use 4-5 Tablespoons of raw or roasted dandelion root per liter of water. Simmer for 20 min with the lid on and allow to cool. Strain and drink - start on 1/4 cup daily and increase slowly to 1 cup 2x a day.

To improve palatability you can add milk/ milk alternative, honey, molasses or liquorice root (add to the dandelion when brewing).