06/06/2020
Consequences of decrease ATP availability:
failure of cell membrane pump (ouabain sensitive Na k ATPase) results in increased intracellular water and Na & decrease intracellular k .This process cause cellular swelling or swelling of organelles.
cellular swelling or hydropic change is charaterized by the large vacuoles in cytoplasm.
swelling of endoplasmic reticulum is one of ultrastructural changes evident of reversible injury.
swelling of mitrochondria progress from reversible low amplitude swelling to irreversible high amplitude swelling which is charaterized by marked dilatation of inner mitochondrial space.
