Unique pharmacy

10/12/2025

Answer without googling…

What’s the only human organ that almost *never* gets cancer?

06/12/2025

06/11/2025

The human brain can anticipate events milliseconds before they actually happen, allowing us to react faster than conscious awareness alone. This predictive ability comes from networks in the brain that continuously analyze patterns, past experiences, and sensory input to forecast immediate outcomes.

These predictions help coordinate movement, decision-making, and responses to potential threats. For example, when catching a ball or avoiding obstacles, the brain calculates likely positions and outcomes before the body moves. This rapid processing occurs below conscious thought, giving humans an edge in survival and daily activities.

Neuroscientists have measured brain activity that signals expected events even before they occur externally. This shows that the brain is not merely reactive but constantly running simulations to stay ahead of reality. It explains phenomena like intuition, reflexes, and the ability to sense danger before it fully manifests.

Understanding how the brain predicts events could lead to innovations in brain-computer interfaces, enhanced training methods, and therapies for disorders where predictive processing is impaired. It also reveals that human perception is not just about observing the present; it is a continuous forecast, a preview generated by the brain to guide action in a complex and fast-moving world.

06/11/2025

A groundbreaking study has revealed that certain proteins in the brain could act as early warning signs for dementia, years before any noticeable symptoms appear. Scientists have identified specific biomarkers that change long before memory loss or cognitive decline becomes evident, offering a potential window for early intervention.

These brain proteins play a crucial role in neural function, and abnormal levels may indicate the beginning of degenerative processes associated with Alzheimer’s and other forms of dementia. By detecting these changes early, doctors could monitor high-risk individuals more closely and implement strategies to slow disease progression.

Early detection is considered one of the most powerful tools in the fight against dementia. Current treatments are limited, but targeting the disease before it takes hold could dramatically improve outcomes and quality of life for millions. Researchers hope that with further studies, simple blood tests or brain scans could measure these protein levels, making early detection accessible and practical.

This discovery also highlights the importance of ongoing research into the biological mechanisms of dementia, offering hope that one day we might be able to prevent or delay its devastating effects.

06/11/2025

In a groundbreaking advance, scientists at the University of British Columbia (UBC) have successfully changed the blood type of a donated human kidney for the first time. This experiment represents a major step toward creating universal donor organs that could be transplanted into any recipient, regardless of blood type compatibility.

Researchers achieved this by using lab-grown enzymes that remove the specific sugar molecules—called antigens—that determine blood type on the surface of red blood cells and organ tissues. In this case, the team used enzymes to strip away A antigens from a Type-A kidney, effectively converting it into Type-O, the universal blood type.

This modification is significant because blood type mismatches are a major cause of organ rejection in transplant recipients. A universal organ could drastically reduce waiting times for patients and improve transplant success rates worldwide. During testing, the altered kidney was connected to a simulated blood flow using Type-O blood, and the organ showed no signs of immune reaction for two days. Even when a mild reaction later occurred, the kidney remained much more stable than in traditional mismatched transplants.

Over half of people on kidney transplant waiting lists are Type-O, meaning they can only receive organs from Type-O donors. If further clinical trials confirm safety and long-term success, this technique could revolutionize organ transplantation—potentially allowing doctors to prepare universal organs ready for any patient, anywhere.

Source:
University of British Columbia, Nature Biomedical Engineering (2025).
“Donor organ’s blood type altered for the first time.”

04/11/2025

Just 20 minutes of sunlight a day stimulates the production of over 200 antimicrobial peptides by the body which help combat fungi, parasites and viruses.

Sunlight triggers the production of antimicrobial peptides (AMPs) through a process that starts with ultraviolet B (UVB) rays, which are a component of sunlight. UVB rays in the skin convert a cholesterol compound into a form of vitamin D3, which boosts the immune system and helps the body produce AMPs that fight pathogens like bacteria, viruses, fungi and parasites.

Additionally, sunlight energizes T cells, which are a key part of the immune response, by making them move faster to sites of infection. This increased movement helps these infection-fighting cells travel more quickly to the site of an infection and launch an immune response.

NO PMID AVAILABLE YET. SOURCE: https://distance.physiology.med.ufl.edu/the-science-of-sunlight-immune-system-benefits-and-risks-explained/

19/10/2025

The human vascular system is a complex network of arteries and veins that supply oxygen and nutrients to the body. The highlighted arteries in the image play crucial roles in delivering blood to the brain and head, including the carotid arteries, which are vital for brain function.

19/10/2025

In a remarkable and unexpected development, a terminal cancer patient has shown significant recovery after being treated with an anti-parasitic dr*g. This surprising case is drawing global attention and could pave the way for new approaches in cancer therapy.

Researchers and clinicians observed that the drg, traditionally used to treat parasitic infections, appeared to target cancer cells in ways conventional therapies often cannot. Early studies suggest that the drg may disrupt the metabolism of cancer cells, weaken their growth, and trigger immune responses that help the body fight tumors more effectively.

While this treatment is still experimental and has only been observed in a limited number of patients, the results are encouraging. The patient’s recovery provides hope that repurposing existing dr*gs could become a faster, more cost-effective route to developing new cancer therapies.

Medical experts caution that more research and clinical trials are needed to determine the safety, optimal dosing, and broader applicability of this approach. Nevertheless, the case highlights the potential of innovative thinking in medicine, sometimes the solutions to life-threatening conditions may lie in unexpected places.

This breakthrough reminds the medical community and patients alike that cancer research continues to evolve rapidly. Every discovery, even one involving a dr*g originally intended for parasites, brings us closer to more effective and potentially life-saving treatments for cancer.

*g

19/10/2025

🧠 A Stanford breakthrough could change the future of autism treatment! Researchers have reversed autism-like behaviors in mice by targeting a lesser-known brain region: the reticular thalamic nucleus.

This area, which filters sensory information, was found to be hyperactive in mice modeling autism, driving symptoms like hypersensitivity, social withdrawal, seizures, and repetitive behaviors. Using an experimental seizure drug (Z944) and a neuromodulation technique called DREADD, the team calmed this hyperactivity, restoring normal behavior. Strikingly, ramping up activity in healthy mice triggered autism-like traits, confirming the region’s key role.

The findings also shed light on why epilepsy often accompanies autism, hinting at shared neural pathways in the thalamus. While still in preclinical stages, this discovery points to a bold new path for precise, biology-based autism treatments. If human studies confirm these results, it could be a game-changer for millions.

paper
“Reticular thalamic hyperexcitability drives autism spectrum disorder behaviors in the Cntnap2 model of autism” by Sung-Soo Jang, Fuga Takahashi and John R. Huguenard, 20 August 2025, Science Advances.

19/10/2025

In a groundbreaking medical achievement, Chinese researchers have successfully reversed Type 1 diabetes in a woman using her own stem cells. For the first time, her body began producing insulin naturally — without external injections. This case marks a historic step toward curing a disease long thought to be permanent.

The scientists reprogrammed the patient’s own cells into induced pluripotent stem cells (iPSCs), which were then transformed into insulin-producing beta cells. After being implanted into her abdomen, these lab-grown cells started functioning like a natural pancreas, releasing insulin in response to blood sugar changes. Out of three participants in the study, she became the first to achieve complete insulin independence.

Experts worldwide are calling this a potential revolution in diabetes treatment. If larger trials confirm the results, stem-cell therapy could eventually replace lifelong insulin injections and lead to personalized regenerative cures for millions living with diabetes. It’s a glimpse into a future where the body’s own cells can heal chronic diseases once deemed incurable.

19/10/2025

Chronic inflammation is a silent driver behind many of the world’s deadliest diseases—from heart disease and diabetes to Alzheimer’s and cancer.

Now, scientists are discovering that one of the body’s most powerful tools in fighting it may not be a drug, but a nerve. The vagus nerve, which runs from the brainstem to organs like the heart and gut, plays a crucial role in regulating inflammation. When functioning properly, it keeps the immune response in balance. But when it malfunctions, chronic inflammation can take hold.

Enter vagus nerve stimulation—a promising bioelectronic therapy that uses electrical pulses to "reset" immune activity and reduce inflammation. Unlike medications, this approach may offer long-term relief without major side effects. Already FDA-approved for epilepsy and depression, vagus nerve stimulation is now being explored for autoimmune conditions like rheumatoid arthritis and Crohn’s disease, as well as neurological disorders such as Alzheimer’s and Parkinson’s.

With researchers working to map the vagus nerve and refine stimulation techniques, this innovative therapy could soon offer millions of patients an alternative to lifelong drug regimens—potentially marking a revolutionary shift in how we treat chronic disease.

REFERENCE:
"Inflammation, vagus nerve stimulation, and your health", Northwell Health (Medically reviewed by Kevin Tracey, MD).

19/10/2025

سائنس دانوں نے پہلی بار انسانی تاریخ میں ایسے افراد کا علاج کامیابی سے کیا ہے جو پیدائشی طور پر مکمل بہرے تھے اور یہ سب صرف ایک خراب جین کو درست کرنے سے ممکن ہوا۔
یہ علاج ایک جدید وائرل جین تھراپی کے ذریعے کیا گیا ہے۔ یعنی، سائنس دانوں نے ایک وائرس کو اس طرح تیار کیا کہ وہ اندرونی کان کے خلیوں تک ایک صحیح جین پہنچا سکے۔
یہ جین جسم کو وہ پروٹین بنانے میں مدد دیتا ہے جو آواز کی لہروں کو برقی سگنلز میں بدلتا ہے، تاکہ دماغ انہیں سن سکے۔
اس علاج کے بعد کئی مریض خصوصاً بچے جو کبھی زندگی میں کوئی آواز نہیں سن پائے تھے اب موسیقی پہچاننے لگے ہیں بارش، قدموں کی چاپ، اور ہلکی آوازیں بھی سننے لگے ہیں