22/08/2025
I still remember this like yesterday.
I was just starting my Neurology residency.
A 24-year-old young man came to the ward in a wheelchair. Before I could talk to him, his attendant pulled me aside: “Doctor, he’s a drug addict. We use together. He likely overdosed. Please don’t tell his family.”
With that frame in mind, I walked up to the patient. His father added: “He had hernia surgery a few days ago. Since then, headache. He's never had a headache before. Today, he seems confused.”
I asked him to stand up and walk.
He looked off.
But in my head I said: “He’s just intoxicated.”
He pointed to his head. “It hurts.”
And I thought: “Of course, you junkie.”
So I gave painkillers and sent him home.
Next day, same patient.
My heart sank.
This time on a stretcher. On oxygen. Unconscious. He had had many seizures overnight. A subsequent CT showed a brain bleed.
The truth: I had missed a dangerous headache.
Today, I would not make this mistake. Because now I use a system. A simple, repeatable system to make sure serious headaches are not missed. I use this, no matter what bias I have.
Always, begin with the basics:
- Airway
- BP
- Pulse
- Oxygen
- Random Blood Sugar
If anything is off → Alarm bells.
Next, I look for anything suggestive of a secondary (dangerous headache). These include [mnemonic: SNOOP]:
- Systemic features like fever or weight loss
- Neurological deficits like objective weakness or confusion (like my patient)
- Out of nowhere i.e. never had a headache before (like my patient)
- Onset age > 40 years
- Papilledema (it's not practical to check everyone's eyes. So simply ask them if they have any acute vision issues).
This sounds good in theory, but in reality...
Patients don’t speak in mnemonics. They tell stories.
If you try to ask them direct, point-blank questions, the quality of information is very low.
You're not getting a diagnosis with low quality information.
So let them speak.
My opening line when I first encounter a patient is simple: “Ji?”
Then silence. Let them talk.
After that, I dig deeper. Here's how [mnemonic: SOCRAAT]:
- Site: Where does it hurt? (ask them to point with hand). Pro tip: It's never the whole head. Push them to localize exactly where it hurts.
- Onset: Since when? How did it start? (the latter of these is my favorite question)
- Character: What type of pain (stabbing, dull, burning)?
- Radiation into the neck or chest?
- Alleviating factors: What makes it better?
- Aggravating factors: What makes it worse?
- Time course: Getting worse, better, or the same?
The process does not end here.
You must do a quick review of systems for symptoms that the patient may have missed.
Ask about:
- Fever, weight loss?
- Vision change or gritty eyes?
- Oral ulcers?
- Chest pain, palpitations?
- Bowel/bladder issues?
- Joint pains, rashes, stiffness?
By this point, you have all the information you need to determine if this is a secondary headache. If so, you'll already have a very good idea which one it is.
Most dangerous secondary headaches fall in 3 groups:
- Vascular (these are sudden onset and maximal in severity from the start)
- Infectious
- Miscellaneous (Ocular or Neoplastic)
[Mnemonic: MiSS GGTT R]
- Meningoencephalitis
- Stroke (ischemic or hemorrhagic, venous or arterial)
- Subarachnoid hemorrhage
- Glaucoma
- Giant cell arteritis
- Trauma
- Tumor
- RCVS
And no — this does not take long. A good, focused history takes only minutes. And can save a life. I feel that it is worth it.
Ask yourself: are you treating every headache the same? Is painkiller and done your default?
If so, you are doing a disservice to your patients and yourself. You have been blessed with the ability to think and help people. Use it!
With our patient flow, it is not practical to document everything we have asked the patient.
But it hardly takes seconds to write: Probable vascular secondary headache. Urgent CT brain.
So please, don't use time as an excuse. People's lives are in your hands (or should I say mind).
P.S. Digging out information is a skill. You'll get better the more you practice with a repeatable system.
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