30/05/2025
🧬 ZYNOME SCIENTIFIC & Life Sciences Enterprises
Proudly Presents
🌟 Online Research Internship
Gene Expression & Bioinformatics Approaches in Human Disease Research
📆 Starts: 14th June 2025
🕐 Duration: 4 Weeks | ⏳ 1–2 Days/Week (Live + Recorded)
🌐 Online Mode: Zoom / Google Meet
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🔬 Internship Overview
Join this hands-on internship designed to introduce you to the fundamental and applied techniques of molecular biology and bioinformatics used in disease gene research—from primer designing to expression analysis, and in silico structural biology tools.
Whether you're exploring cancer biology, neurogenetics, or rare genetic disorders, this internship equips you with real research skills to excel in modern molecular science.
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📚 What You'll Learn
✅ Understand gene expression and its role in disease
✅ Design primers and plan qPCR experiments
✅ Use bioinformatics tools to analyze DNA/protein sequences
✅ Perform variant and mutation effect analysis
✅ Model protein structures using SWISS-MODEL
✅ Visualize & interpret fold change from qPCR data
✅ Draft short scientific reports and abstracts
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🗓️ Internship Weekly Plan
📖 Week 1: Introduction to Gene Expression in Disease
● Molecular biology basics of gene expression
● Overview of human disease gene databases (NCBI, OMIM, GeneCards, PubMed)
● Selecting a disease-related gene for research
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🧪 Week 2: Primer Designing & Experimental Planning
● Primer design using Primer-BLAST and SnapGene(Primer3)
● qPCR reaction setup (controls, reagents, conditions)
● Hands-on task: Design a primer pair for your selected gene
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🧬 Week 3: Bioinformatics Tools for Sequence & Mutation Analysis
● Sequence alignment with MEGA / Clustal Omega
● Mutation impact analysis (SIFT, PolyPhen, dbSNP)
● Structural protein modeling using SWISS-MODEL
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📊 Week 4: Data Interpretation & Research Report
● ΔCt and ΔΔCt method explained
● Fold change calculation from mock or sample qPCR data
● Data visualization using graphs
● Report writing: Abstract → Methods → Results → Discussion
● Final Presentations by Top Interns
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🎓 Who Can Join?
● BS / MS students in Genetics, Molecular Biology, Bioinformatics, Biotech, MBBS, Pharm.D
● Passionate individuals seeking practical research exposure
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🏅 What You’ll Get
● Certificate of Internship (Verified by Zynome Scientific & Life Sciences Enterprises)
● Research report template + molecular protocol sheets
● Access to tools, databases, and project-based tasks
● Personalized feedback on your project work
● Top interns will receive a Letter of Recommendation
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💸 Internship Fee:
$35 for International Participants
Only 8000 PKR for Pakistani Participants
(Early bird and group discounts available)
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📍 Registration
📝 Apply Now: https://forms.gle/2wrmmnUX7Ne6UQXp6
📱 Contact: +923248498456 | 📧 info.lifescience.edu@gmail.com
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