Oncology in Clinical Practice

Strona główna
Polska
Warsaw
Oncology in Clinical Practice

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29/12/2025

This retrospective analysis evaluated acute and late toxicities of postoperative adjuvant IMRT with a simultaneous integrated boost (IMRT-SIB) in oral cavity squamous cell carcinoma (SCCHN) patients. Toxicities were mostly grade 1–2, with no grade ≥ 3 events; late xerostomia/dysphagia/hoarseness were generally mild and improved over time. The findings support parotid-sparing IMRT to reduce long-term xerostomia and help preserve quality of life.
Authors: Siddharth Arora, Kriti Grover, Prarabdh Singh, Nitesh Mohan

17/12/2025

With the expected growth in cancer incidence, screening programs and early diagnosis are of great importance. Novel digital, internet-based methods have the potential to increase awareness among patients, boosting early detection rates. This review paper focuses on how awareness of cancer screening programs can be disseminated via the internet and social media platforms, including mHealth and web-based education.

Authors: Muazez Küçükkaya, Esma Demirezen

15/12/2025

This exceptional case report — a woman living disease-free 47 years after Ewing sarcoma treatment — highlights why lifelong follow-up is essential in long-term survivors, due to the risk of late relapse, secondary neoplasms, and pathological fractures (including around major biological events such as pregnancy).

Authors: Piotr Remiszewski, Maryna Rubach, Anna M. Czarnecka
📖 Read the full article: https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/108264

10/12/2025

A remarkable long-term remission in advanced NSCLC: this case report presents a 52-year-old patient who, after relapse with a solitary brain metastasis, achieved a durable complete response to nivolumab following stereotactic radiosurgery and systemic therapy.
Authors: Monika Żeleźnicka, Joanna Filipow, Filip Grydź, Tomasz Sarosiek
Read the full case report at:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/107065

09/12/2025

This recent systematic review summarizes toripalimab’s mechanism of action, clinical activity and safety profile in patients with esophageal squamous cell carcinoma (ESCC). Across randomized clinical trials, toripalimab combined with chemotherapy improved survival and pathological responses, with manageable toxicity—supporting its growing role in ESCC management.

Authors: Natalia Picheta, Julia Piekarz, Katarzyna Szklener
📖 Read the full article:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/107560/

02/12/2025

Cognitive impairment is common in older adults with cancer and can have impact on anti-cancer therapy. This study identifies depression, lower education, and reduced handgrip strength as key risk factors, emphasizing the need for early cognitive screening in geriatric oncology.

Authors: Teodoro J. Oscanoa, Edwin Cieza-Macedo, Roman Romero-Ortuno
📄 Full text available at:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/107861

26/11/2025

Histological transformation is a known mechanism of resistance to EGFR-TKIs in NSCLC. This case report presents a transformation from non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) during osimertinib therapy, with persistence of the original EGFR mutation. It underscores the importance of re-biopsy to determine resistance mechanisms and guide further treatment strategies.
Authors: Aleksandra Łomża-Łaba, Natalia Krzyżanowska, Magdalena Wójcik-Superczyńska, Iwona Paśnik, Jarosław Buczkowski, Paweł Krawczyk, Janusz Milanowski
📖 Read the full article: https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/104391

24/11/2025

Could the gut microbiome influence chemoimmunotherapy outcomes in small-cell lung cancer patients?
In this case study of two SCLC patients with markedly different outcomes, higher microbiome diversity and greater abundance of bacterial families such as Lachnospiraceae and Akkermansiaceae were associated with prolonged response. The findings suggest that gut microbial composition may serve as a predictive biomarker of treatment efficacy.

Authors: Anna Grenda, Ewelina Iwan, Paweł Krawczyk, Arkadiusz Bomba, Izabela Chmielewska, Katarzyna Bielińska, Aleksandra Grzywna, Michał Szczyrek, Tomasz Jankowski, Robert Kieszko, Natalia Galant, Janusz Milanowski

📖 Read the full text:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/105103

21/11/2025

Automated deep learning annotation is transforming neuroradiology, but how does it compare to human experts? This is the first meta-analysis on vestibular schwannoma segmentation for Gamma Knife to compare deep-learning algorithms to humans in terms of accuracy.

Authors: Anna Łajczak, Paweł Łajczak
Read the full text at:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/106634/84545

19/11/2025

Breast cancer survivorship requires vigilant monitoring for therapy-related complications. This case report illustrates tamoxifen-induced hepatotoxicity and a symptomatic Tarlov cyst, emphasizing the need for comprehensive long-term monitoring.

Authors: Omer Esmez, Gulnihal Deniz, Merve Yildiz Esmez
📄 Full text available at:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/106126

24/10/2025

Doxorubicin extravasation is related to a high risk of severe ulceration and necrosis. This case of a 71-year-old female shows that prompt intervention with DMSO (dimethyl sulfoxide) and continuous cooling enabled full recovery—highlighting this effective management strategy.

Authors: Karolina Potemska, Dominik Dubieński, Beata Śniecikowska, Magdalena Sobczak, Sylwia Dębska-Szmich
Available at:
https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/107156

23/10/2025

How effective is everolimus + exemestane after CDK4/6 inhibitor use in hormone receptor-positive metastatic breast cancer?
This real-world study of 69 patients from a UK tertiary cancer centre reports a median progression-free survival (PFS) of 5 months for this treatment combination. Findings highlight the limited efficacy post-CDK inhibition and emphasize the need for alternative strategies.
Authors: Smriti Gaur, Jill Bishop
📖 Read the full article: https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/106191

Adres

Ulica Roentgena 5
Warsaw
02-781

Strona Internetowa

https://journals.viamedica.pl/oncology_in_clinical_practice, https://www.researchgate.net/journal/Oncology-in-Clinical-P

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Zdrowie i medycyna