11/14/2025
TW: The first known death from alpha-gal syndrome, a serious allergy to mammalian meat and byproducts caused by a Lone Star Tick bite, has now been confirmed. After months of investigation, researchers at the University of Virginia School of Medicine determined that a 47-year-old man from New Jersey died from a severe allergic reaction triggered hours after eating a hamburger. Alpha-gal syndrome (AGS) occurs when the Lone Star Tick transmits a sugar molecule found in mammals, which can cause delayed allergic reactions to beef, pork, lamb, and high-fat dairy. Symptoms often appear 3–6 hours after eating and can include nausea, diarrhea, stomach pain, hives, difficulty breathing, or anaphylaxis.
This heartbreaking case highlights the urgent need for greater awareness, early recognition of symptoms, and improved clinician education. Many patients and even healthcare providers remain unfamiliar with AGS despite its rapid increase across the United States as tick populations expand into new regions. FARE remains committed to raising awareness, supporting research, and empowering families with accurate, accessible information.