Laser Therapy U

Laser Therapy U Official page for Laser Therapy University -
the leader in Photobiomodulation Education

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home ca...
11/08/2025

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home care with laser therapy. They will explore how providing at-home laser therapy gives patients a fast, easy, and convenient way to improve function and strength, decrease pain and inflammation, improve tissue repair and more. Additionally, attendees will learn implementation strategies for starting an at-home laser therapy program and generating passive income for the practice.

Key Talking Points:
- Understanding different types of home use therapeutic lasers and where they fit into a multi-modal approach to patient care
- How at-home laser therapy improves compliance and outcomes while growing your practice
- Different methods for implementing an at-home laser therapy rental program in your clinic, including how to prescribe, collect payment, reprocess rental devices, and more

REGISTER:https://register.gotowebinar.com/register/2848773505730476381?source=social

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home ca...
11/07/2025

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home care with laser therapy. They will explore how providing at-home laser therapy gives patients a fast, easy, and convenient way to improve function and strength, decrease pain and inflammation, improve tissue repair and more. Additionally, attendees will learn implementation strategies for starting an at-home laser therapy program and generating passive income for the practice.
REGISTER: https://register.gotowebinar.com/register/2848773505730476381?source=social

Key Talking Points:
- Understanding different types of home use therapeutic lasers and where they fit into a multi-modal approach to patient care
- How at-home laser therapy improves compliance and outcomes while growing your practice
- Different methods for implementing an at-home laser therapy rental program in your clinic, including how to prescribe, collect payment, reprocess rental devices, and more

๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒPraveen R. Arany BDS, MDS, MMSc, PhDObjectivesThe use of low doses of photons (light) in biolo...
11/07/2025

๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ
Praveen R. Arany BDS, MDS, MMSc, PhD

Objectives
The use of low doses of photons (light) in biological tissues to modulate (inhibit or stimulate) responses is termed photobiomodulation (PBM). This nonthermal, noninvasive, and nonsurgical light treatment has been reported to reduce pain or inflammation, modulate immune responses, and promote tissue healing and regeneration. These fundamental pathophysiological responses underlie several oral and dental diseases, highlighting the broad scope of PBM interventions such as alleviating pain, discomfort, and swelling postsurgical procedures, including third-molar extractions, managing oncotherapy-associated mucositis and temporomandibular joint disorders, and promoting accelerated orthodontic tooth movements and implant osseointegration.
Search Strategy, Citation Sources, and Data Elements
This narrative review provides the state-of-the-art in the PBM field, including history, terminology, mechanisms, devices, safety, regulations, and policy. The primary emphasis of this work is to outline the advances in mechanistic insights and clinical dosing paradigms that enable the safe and effective use of this therapy.
Overall Conclusions
The importance of fundamental PBM education and training concepts focusing on light-tissue interactions, target tissue composition, evoked therapeutic biological responses, clinical diagnosis, and rationalized dose prescriptions is emphasized. Furthermore, several issues and logistical concerns should be addressed to enable the routine use of this innovative nonpharmacological treatment. A succinct version of this article is available as the American Dental Association Technical Report no. 189 Standards Committee on Dental Products Working Group 6.58.

https://www.sciencedirect.com/science/article/pii/S2772414X25000027

๐…๐ซ๐ž๐ž ๐–๐ž๐›๐ข๐ง๐š๐ซ, ๐“๐ก๐ฎ๐ซ๐ฌ๐๐š๐ฒ, ๐๐จ๐ฏ๐ž๐ฆ๐›๐ž๐ซ ๐Ÿ๐ŸŽ๐ญ๐ก @ ๐Ÿ:๐ŸŽ๐ŸŽ ๐๐Œ ๐„๐“ - REGISTER: https://register.gotowebinar.com/register/284877350573047...
11/06/2025

๐…๐ซ๐ž๐ž ๐–๐ž๐›๐ข๐ง๐š๐ซ, ๐“๐ก๐ฎ๐ซ๐ฌ๐๐š๐ฒ, ๐๐จ๐ฏ๐ž๐ฆ๐›๐ž๐ซ ๐Ÿ๐ŸŽ๐ญ๐ก @ ๐Ÿ:๐ŸŽ๐ŸŽ ๐๐Œ ๐„๐“ -
REGISTER: https://register.gotowebinar.com/register/2848773505730476381?source=social

Whether your patients walk on two or four legs, itโ€™s not always feasible to provide multiple in-clinic treatments a week. We all know life sometimes gets in the way - work, school, traffic, travel, and more can often cause gaps in much-needed treatment regimens. Fortunately, with an at-home laser therapy program, you can offer a convenient solution to continue care outside the clinic, as part of a multi-model approach to care.

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home care with laser therapy. They will explore how providing at-home laser therapy gives patients a fast, easy, and convenient way to improve function and strength, decrease pain and inflammation, improve tissue repair and more. Additionally, attendees will learn implementation strategies for starting an at-home laser therapy program and generating passive income for the practice.

Key Talking Points:
- Understanding different types of home use therapeutic lasers and where they fit into a multi-modal approach to patient care
- How at-home laser therapy improves compliance and outcomes while growing your practice
- Different methods for implementing an at-home laser therapy rental program in your clinic, including how to prescribe, collect payment, reprocess rental devices, and more

๐„๐Ÿ๐Ÿ๐ž๐œ๐ญ๐ฌ ๐จ๐Ÿ ๐ฉ๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐จ๐ง ๐ฆ๐ฎ๐ฅ๐ญ๐ข๐ฉ๐ฅ๐ž ๐ก๐ž๐š๐ฅ๐ญ๐ก ๐จ๐ฎ๐ญ๐œ๐จ๐ฆ๐ž๐ฌ: ๐š๐ง ๐ฎ๐ฆ๐›๐ซ๐ž๐ฅ๐ฅ๐š ๐ซ๐ž๐ฏ๐ข๐ž๐ฐ ๐จ๐Ÿ ๐ซ๐š๐ง๐๐จ๐ฆ๐ข๐ณ๐ž๐ ๐œ๐ฅ๐ข๐ง๐ข๐œ๐š๐ฅ ๐ญ๐ซ๐ข๐š๐ฅ๐ฌYejun Son , e...
11/06/2025

๐„๐Ÿ๐Ÿ๐ž๐œ๐ญ๐ฌ ๐จ๐Ÿ ๐ฉ๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐จ๐ง ๐ฆ๐ฎ๐ฅ๐ญ๐ข๐ฉ๐ฅ๐ž ๐ก๐ž๐š๐ฅ๐ญ๐ก ๐จ๐ฎ๐ญ๐œ๐จ๐ฆ๐ž๐ฌ: ๐š๐ง ๐ฎ๐ฆ๐›๐ซ๐ž๐ฅ๐ฅ๐š ๐ซ๐ž๐ฏ๐ข๐ž๐ฐ ๐จ๐Ÿ ๐ซ๐š๐ง๐๐จ๐ฆ๐ข๐ณ๐ž๐ ๐œ๐ฅ๐ข๐ง๐ข๐œ๐š๐ฅ ๐ญ๐ซ๐ข๐š๐ฅ๐ฌ
Yejun Son , et. al

Background
Photobiomodulation (PBM) is a non-invasive therapy increasingly used for pain, inflammation, and tissue repair, yet a comprehensive synthesis of its effectiveness across multiple health outcomes remains lacking. Herein, we aimed to systematically assess the clinical effects and strength of evidence for PBM across a wide range of health outcomes using data from existing meta-analyses of randomized controlled trials (RCTs).
[...]
Results
A total of 15 meta-analyses encompassing 204 RCTs and over 9000 participants were included, covering 35 health endpoints across 15 disease conditions. PBM showed significant effects for 12 outcomes, with moderate certainty of evidence supporting improvements in burning mouth syndrome (pain reduction, eSMD โˆ’ 0.92 [95% CI โˆ’ 1.38 to โˆ’ 0.46]), knee osteoarthritis (disability, 0.65 [0.14 to 1.15]), fibromyalgia (fatigue, 1.25 [0.63 to 1.87]), androgenetic alopecia (hair density, 1.32 [1.00 to 1.63]), and cognitive function (0.49 [0.14 to 0.84]). Most other outcomes exhibited low or very low certainty due to heterogeneity or small-study effects. P-curve and funnel plot analyses indicated evidential value for several outcomes, though potential publication bias was identified in some.

Conclusions
PBM appeared beneficial for some health conditions, such as the strongest support for fibromyalgia, osteoarthritis-related disability, and cognitive impairment. However, given the overall low-to-moderate certainty of evidence for most endpoints, further high-quality trials and standardization of PBM protocols are warranted before widespread clinical adoption.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12326686/

Whether your patients walk on two or four legs, itโ€™s not always feasible to provide multiple in-clinic treatments a week...
11/05/2025

Whether your patients walk on two or four legs, itโ€™s not always feasible to provide multiple in-clinic treatments a week. We all know life sometimes gets in the way - work, school, traffic, travel, and more can often cause gaps in much-needed treatment regimens. Fortunately, with an at-home laser therapy program, you can offer a convenient solution to continue care outside the clinic, as part of a multi-model approach to care.

Join Drs. Christopher Carraway and Debbie Torraca as they discuss how to bridge the gap between in-clinic and at-home care with laser therapy. They will explore how providing at-home laser therapy gives patients a fast, easy, and convenient way to improve function and strength, decrease pain and inflammation, improve tissue repair and more. Additionally, attendees will learn implementation strategies for starting an at-home laser therapy program and generating passive income for the practice.

Key Talking Points:
- Understanding different types of home use therapeutic lasers and where they fit into a multi-modal approach to patient care
- How at-home laser therapy improves compliance and outcomes while growing your practice
- Different methods for implementing an at-home laser therapy rental program in your clinic, including how to prescribe, collect payment, reprocess rental devices, and more

Register: https://register.gotowebinar.com/register/2848773505730476381?source=social

๐ˆ๐ง๐ญ๐ซ๐š๐ง๐š๐ฌ๐š๐ฅ ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ ๐Ÿ๐จ๐ซ ๐๐ซ๐š๐ข๐ง ๐‚๐จ๐ง๐๐ข๐ญ๐ข๐จ๐ง๐ฌ: ๐€ ๐‘๐ž๐ฏ๐ข๐ž๐ฐShin Hyuk YooThe effects of low-level laser irradiat...
11/05/2025

๐ˆ๐ง๐ญ๐ซ๐š๐ง๐š๐ฌ๐š๐ฅ ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ ๐Ÿ๐จ๐ซ ๐๐ซ๐š๐ข๐ง ๐‚๐จ๐ง๐๐ข๐ญ๐ข๐จ๐ง๐ฌ: ๐€ ๐‘๐ž๐ฏ๐ข๐ž๐ฐ
Shin Hyuk Yoo

The effects of low-level laser irradiation on cells and tissues, known as photobiomodulation therapy (PBMT), are the basis of photomedicine. Several investigations have evaluated the therapeutic effects of PBMT for neuronal regeneration and differentiation in animal models and humans. Recently, intranasal PBMT (iN-PBMT) has shown potential as a treatment method for neurologic disorders. In this review, we have summarized the various modes of iN-PBMT delivery and their application in the treatment of brain disorders.

https://www.jkslms.or.kr/journal/view.html?doi=10.25289%2FML.2021.10.3.132

๐‹๐ข๐ ๐ก๐ญ ๐›๐ฎ๐œ๐ค๐ž๐ญ๐ฌ ๐š๐ง๐ ๐ฅ๐š๐ฌ๐ž๐ซ ๐›๐ž๐š๐ฆ๐ฌ: ๐ฆ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ฆ๐ฌ ๐š๐ง๐ ๐š๐ฉ๐ฉ๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง๐ฌ ๐จ๐Ÿ ๐ฉ๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง (๐๐๐Œ) ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒDavid W Frankowski, Luigi ...
11/04/2025

๐‹๐ข๐ ๐ก๐ญ ๐›๐ฎ๐œ๐ค๐ž๐ญ๐ฌ ๐š๐ง๐ ๐ฅ๐š๐ฌ๐ž๐ซ ๐›๐ž๐š๐ฆ๐ฌ: ๐ฆ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ฆ๐ฌ ๐š๐ง๐ ๐š๐ฉ๐ฉ๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง๐ฌ ๐จ๐Ÿ ๐ฉ๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง (๐๐๐Œ) ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ
David W Frankowski, Luigi Ferrucci, Praveen R Arany, Dawn Bowers, Janis T Eells, Francisco Gonzalez-Lima, Nicole L Lohr, Brendan J Quirk, Harry T Whelan, Edward G Lakatta

Photobiomodulation (PBM) therapy, a non-thermal light therapy using nonionizing light sources, has shown therapeutic potential across diverse biological processes, including aging and age-associated diseases. In 2023, scientists from the National Institute on Aging (NIA) Intramural and Extramural programs convened a workshop on the topic of PBM to discuss various proposed mechanisms of PBM action, including the stimulation of mitochondrial cytochrome C oxidase, modulation of cell membrane transporters and receptors, and the activation of transforming growth factor-ฮฒ1. They also reviewed potential therapeutic applications of PBM across a range of conditions, including cardiovascular disease, retinal disease, Parkinsonโ€™s disease, and cognitive impairment. Workshop participants largely agreed that PBM holds immense potential as a safe and effective therapeutic approach for a wide range of age-related diseases and cognitive decline. While further research is needed to fully elucidate its mechanisms and optimize treatment protocols, the findings presented at the NIA workshop provide strong evidence for the continued investigation and clinical translation of this promising, inexpensive, safe technology, to aging and age-associated diseases. Here, we review the research presented and discussion held at the meeting. In addition, the text has been updated, where applicable, with recent research findings that have been made since the meeting occurred.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12181550/

๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ข๐ง ๐จ๐œ๐ฎ๐ฅ๐š๐ซ ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ: ๐œ๐ฎ๐ซ๐ซ๐ž๐ง๐ญ ๐ฌ๐ญ๐š๐ญ๐ฎ๐ฌ ๐š๐ง๐ ๐Ÿ๐ฎ๐ญ๐ฎ๐ซ๐ž ๐ฉ๐ž๐ซ๐ฌ๐ฉ๐ž๐œ๐ญ๐ข๐ฏ๐ž๐ฌHasan Chichan, et. alPhotobiomodulation has ...
11/03/2025

๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ข๐ง ๐จ๐œ๐ฎ๐ฅ๐š๐ซ ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ: ๐œ๐ฎ๐ซ๐ซ๐ž๐ง๐ญ ๐ฌ๐ญ๐š๐ญ๐ฎ๐ฌ ๐š๐ง๐ ๐Ÿ๐ฎ๐ญ๐ฎ๐ซ๐ž ๐ฉ๐ž๐ซ๐ฌ๐ฉ๐ž๐œ๐ญ๐ข๐ฏ๐ž๐ฌ
Hasan Chichan, et. al

Photobiomodulation has been known to have potential medicinal effects for ages. It involves the use of specific wavelengths to target specific regions in the cell. Different health conditions have been reported to be treated with exposure to light such as cardiovascular conditions, inflammatory diseases, infectious diseases, and most importantly ocular diseases. This review specifically targets the treatment of retinal diseases including age-related macular degeneration, diabetic macular edema, myopia and acute retinal light injury with photobiomodulation. Red light is used in this therapy since this wavelength has lower frequency and hence minimal chance of causing any damage. Red light has the potential to pe*****te cellular structures such as mitochondria and facilitate cellular processes. For ocular diseases, the target wavelength ranges between 630 to 800 nm. In most of the cases the primary target for red light is the cytochrome C oxidase enzyme in mitochondria, which alters the gene expression and promotes cellular energy production. Clinical evidence shows improvement of visual activity and reduction in thickness of retina post treatment. Future prospects of photobiomodulation involve target-specific treatment, combinational therapy to treat complex retinal diseases including gene therapy, and longitudinal studies to predict long-term efficacy and the chance of any recurrence in the patients. Hence the future of photobiomodulation holds significant potential in medicine especially in ocular diseases characterized by progress in research, technology, and clinical trials.

https://pmc.ncbi.nlm.nih.gov/articles/PMC11754031/

๐€ ๐†๐ซ๐š๐ง๐ญ ๐‘๐ž๐ฉ๐จ๐ซ๐ญ: ๐„๐ฑ๐š๐ฆ๐ข๐ง๐ข๐ง๐  ๐ญ๐ก๐ž ๐„๐Ÿ๐Ÿ๐ข๐œ๐š๐œ๐ฒ ๐จ๐Ÿ ๐‘๐ž๐ฆ๐จ๐ญ๐ž ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ ๐ข๐ง ๐€๐๐จ๐ฅ๐ž๐ฌ๐œ๐ž๐ง๐ญ๐ฌ ๐ฐ๐ข๐ญ๐ก ๐Œ๐š๐ฃ๐จ๐ซ ๐ƒ๐ž๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐ฏ๐ž ๐ƒ๐ข๐ฌ๐จ๐ซ๐๐ž...
10/31/2025

๐€ ๐†๐ซ๐š๐ง๐ญ ๐‘๐ž๐ฉ๐จ๐ซ๐ญ: ๐„๐ฑ๐š๐ฆ๐ข๐ง๐ข๐ง๐  ๐ญ๐ก๐ž ๐„๐Ÿ๐Ÿ๐ข๐œ๐š๐œ๐ฒ ๐จ๐Ÿ ๐‘๐ž๐ฆ๐จ๐ญ๐ž ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ ๐ข๐ง ๐€๐๐จ๐ฅ๐ž๐ฌ๐œ๐ž๐ง๐ญ๐ฌ ๐ฐ๐ข๐ญ๐ก ๐Œ๐š๐ฃ๐จ๐ซ ๐ƒ๐ž๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐ฏ๐ž ๐ƒ๐ข๐ฌ๐จ๐ซ๐๐ž๐ซ
Adriano Alberti, et al

Major depressive disorder (MDD) is a prevalent mental health condition affecting a significant portion of the population worldwide. This condition can impact individuals of all ages, including adolescents, leading to an impact on various aspects of their lives. Adolescence is a crucial phase of human development, characterized by several neurobiological changes. The onset of MDD during this period can result in damage not only to teenagers but also might have long-lasting implications for their future as adults. Notably, the onset of MDD in adolescents is often associated with various biomarkers, such as increased levels of inflammatory cytokines (e.g., IL-6, TNF-ฮฑ), oxidative stress markers, and alterations in neurotransmitter levels, indicating a complex interplay of biological factors. Therefore, early intervention is essential for addressing MDD during this phase. Photobiomodulation therapy (PBMT) emerges as an innovative and promising approach that utilizes light, especially in the near-infrared (NIR) and red spectra, to trigger biological and therapeutic effects. Notably, targeting the skull and abdomen with PBMT might explore the bidirectional communication between the intestinal system and the central nervous system in a remote and/or systemic way. In this context, we present the rationale and design of an ongoing study aiming to assess the efficacy of PBMT on depressive symptoms and biomarkers associated with oxidative stress and mitochondrial function in adolescents with MDD.

https://www.mdpi.com/2304-6732/11/9/839

๐“๐ก๐ž ๐ž๐Ÿ๐Ÿ๐ž๐œ๐ญ๐ข๐ฏ๐ž๐ง๐ž๐ฌ๐ฌ ๐จ๐Ÿ ๐“๐ซ๐š๐ง๐ฌ๐œ๐ซ๐š๐ง๐ข๐š๐ฅ ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ (๐ญ๐๐๐Œ) ๐จ๐ง ๐ซ๐ž๐๐ฎ๐œ๐ข๐ง๐  ๐š๐ง๐ฑ๐ข๐ž๐ญ๐ฒ, ๐๐ž๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐จ๐ง, ๐š๐ง๐ ๐จ๐ฉ๐ข๐จ๐ข๐ ๐œ๐ซ๐š๐ฏ๐ข๐ง๐  ...
10/30/2025

๐“๐ก๐ž ๐ž๐Ÿ๐Ÿ๐ž๐œ๐ญ๐ข๐ฏ๐ž๐ง๐ž๐ฌ๐ฌ ๐จ๐Ÿ ๐“๐ซ๐š๐ง๐ฌ๐œ๐ซ๐š๐ง๐ข๐š๐ฅ ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ (๐ญ๐๐๐Œ) ๐จ๐ง ๐ซ๐ž๐๐ฎ๐œ๐ข๐ง๐  ๐š๐ง๐ฑ๐ข๐ž๐ญ๐ฒ, ๐๐ž๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐จ๐ง, ๐š๐ง๐ ๐จ๐ฉ๐ข๐จ๐ข๐ ๐œ๐ซ๐š๐ฏ๐ข๐ง๐  ๐ข๐ง ๐ฉ๐š๐ญ๐ข๐ž๐ง๐ญ๐ฌ ๐ฎ๐ง๐๐ž๐ซ๐ ๐จ๐ข๐ง๐  ๐ฆ๐ž๐ญ๐ก๐š๐๐จ๐ง๐ž ๐ฆ๐š๐ข๐ง๐ญ๐ž๐ง๐š๐ง๐œ๐ž ๐ญ๐ซ๐ž๐š๐ญ๐ฆ๐ž๐ง๐ญ: ๐š ๐๐จ๐ฎ๐›๐ฅ๐ž-๐›๐ฅ๐ข๐ง๐, ๐ซ๐š๐ง๐๐จ๐ฆ๐ข๐ณ๐ž๐, ๐œ๐จ๐ง๐ญ๐ซ๐จ๐ฅ๐ฅ๐ž๐ ๐ญ๐ซ๐ข๐š๐ฅ
Helya Helali, et al

Background [...]

Methods
This randomized controlled clinical trial included two groups of substance-dependent patients undergoing MMT. They were randomly assigned to receive tPBMT or a sham tPBMT. The intervention group received PBM in the form of Light- Emitting Diodes (LEDs) for four minutes of light exposure at 810 nm wavelength producing 250 mW/cm2 when applied to 4 mm skin depth (totaling 60 J/cm2) in both forehead locations. The levels of anxiety, depression, and opioid craving were compared between the two groups before and after the intervention, as well as at one-month and three-month follow-up assessments.

Results
Both groups consisted of 32 (91.4%) males and 3 (8.6%) females, with the mean age of patients in the intervention group being 37.97 ยฑ 10.58 years, and 39.66 ยฑ 9.94 years in the control group (P = 0.495). There were no significant differences between the two groups in terms of depression, anxiety, and opioid craving scale scores before the intervention (p>0.05). However, the tPBMT group had statistically significant reductions in their scores compared to the sham tPBMT group. (p

๐“๐š๐ซ๐ ๐ž๐ญ๐ข๐ง๐  ๐€๐ง๐ฑ๐ข๐ž๐ญ๐ฒ ๐ฐ๐ข๐ญ๐ก ๐‹๐ข๐ ๐ก๐ญ: ๐Œ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ญ๐ข๐œ ๐š๐ง๐ ๐‚๐ฅ๐ข๐ง๐ข๐œ๐š๐ฅ ๐ˆ๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐ข๐ง๐ญ๐จ๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ: ๐€ ๐Œ๐ข๐ง๐ข ๐๐š๐ซ๐ซ๐š๐ญ๐ข๐ฏ๐ž ๐‘๐ž๐ฏ๐ข๐ž๐ฐB...
10/29/2025

๐“๐š๐ซ๐ ๐ž๐ญ๐ข๐ง๐  ๐€๐ง๐ฑ๐ข๐ž๐ญ๐ฒ ๐ฐ๐ข๐ญ๐ก ๐‹๐ข๐ ๐ก๐ญ: ๐Œ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ญ๐ข๐œ ๐š๐ง๐ ๐‚๐ฅ๐ข๐ง๐ข๐œ๐š๐ฅ ๐ˆ๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐ข๐ง๐ญ๐จ
๐๐ก๐จ๐ญ๐จ๐›๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ: ๐€ ๐Œ๐ข๐ง๐ข ๐๐š๐ซ๐ซ๐š๐ญ๐ข๐ฏ๐ž ๐‘๐ž๐ฏ๐ข๐ž๐ฐ
Buliman, Anca, et al

Anxiety disorders are common and disabling, with current pharmacological and psychotherapeutic options often limited by suboptimal efficacy or adverse effects. Transcranial photobiomodulation (tPBM), a light-based neuromodulation technique using near-infrared wavelengths (typically 810-1064 nm), has emerged as a potential alternative through its effects on mitochondrial bioenergetics, neuroinflammation, and neuroplasticity. The objective of this mini review is to review mechanistic rationale and summarize recent preclinical and clinical findings on tPBM for anxiety disorders. A narrative search of PubMed, Web of Science, and Google Scholar was performed, focusing on experimental animal studies and clinical investigations published in the last decade that examined tPBM or related lowlevel light therapies for anxiety outcomes. Preclinical studies consistently report that repeated NIR exposure (e.g., 810 nm, 4-8 J/cm2) reduces anxiety-like behaviors in rodents, accompanied by increased serotonin levels, decreased nitric oxide, and modulation of microglial polarization. Early clinical studies--including small open-label trials (n = 10-15) and one randomized controlled trial (n = 70)--suggest that tPBM (810-830 nm, applied for 420 minutes, single or repeated sessions) can reduce Hamilton Anxiety scores and improve sleep and mood, with minimal adverse effects. However, study designs are heterogeneous, with small sample sizes and short follow-up durations. tPBM shows promise as a safe, noninvasive intervention for anxiety, supported by converging mechanistic and preliminary clinical evidence. Nonetheless, current findings remain exploratory, and large, rigorously designed randomized controlled trials are essential to establish efficacy, optimize dose parameters, and assess long-term outcomes.

https://bioclima.ro/Balneo846.pdf

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