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Laser Therapy U, Atlanta, GA (2026)

01/02/2026

𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐜𝐨𝐦𝐛𝐢𝐧𝐞𝐝 𝐰𝐢𝐭𝐡 𝐬𝐭𝐚𝐭𝐢𝐜 𝐦𝐚𝐠𝐧𝐞𝐭𝐢𝐜 𝐟𝐢𝐞𝐥𝐝 𝐢𝐬 𝐛𝐞𝐭𝐭𝐞𝐫 𝐭𝐡𝐚𝐧 𝐩𝐥𝐚𝐜𝐞𝐛𝐨 𝐢𝐧 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐰𝐢𝐭𝐡 𝐟𝐢𝐛𝐫𝐨𝐦𝐲𝐚𝐥𝐠𝐢𝐚: 𝐚 𝐫𝐚𝐧𝐝𝐨𝐦𝐢𝐳𝐞𝐝 𝐩𝐥𝐚𝐜𝐞𝐛𝐨-𝐜𝐨𝐧𝐭𝐫𝐨𝐥𝐥𝐞𝐝 𝐭𝐫𝐢𝐚𝐥
Neide F Ribeiro, CP Ernesto, Douglas S Johnson, Timothy Demchak, Caroline M Machado, B DIAS Luana, Marcelo F De Oliveira, M LINO Matheus, Wesley D RODRIGUES, Jonathan Santo, Carolina N De Barros, Heliodora L Casalechi, Shaiane S Tomazoni

BACKGROUND [...]

AIM
We aimed to investigate the effects of using PBMT-sMF versus a placebo on reduction of the degree-of-pain rating, impact of fibromyalgia, pain intensity, and satisfaction with treatment in patients with fibromyalgia.

DESIGN
A prospectively registered, monocentric, randomized placebo-controlled trial, with blinding of patients, therapists, and assessors, was performed.

SETTING
The study was conducted at the Laboratory of Phototherapy and Innovative Technologies in Health (LaPIT) in Brazil, between March and October 2020.

POPULATION
Ninety female patients with fibromyalgia were randomized to undergo either PBMT-sMF (N.=45) or placebo (N.=45) treatment.

METHODS
Patients from both groups received nine treatment sessions, three times a week, for 3 weeks. Clinical outcomes were collected at baseline, the end of treatment, and at the follow-up appointment 4 weeks post-treatment. The primary outcome was the degree-of-pain rating, measured by the reduction of the tender point count.

RESULTS
A decrease in the degree-of-pain rating was observed in patients allocated to the PBMT-sMF group, decreasing the number of tender points when compared to placebo group at the end of treatment (P

01/01/2026

Join Dr. Christopher Carraway for a discussion on mastering the core principles of laser therapy and how to clinically integrate this modality into your current care plans. Dr. Carraway will be sharing ways you can become a laser therapy Super User in 2026!

Key Talking Points:
- Review the science behind the method of action of laser therapy in managing pain, reducing inflammation, enhancing muscle recovery and more
- How to build custom protocols for treating any condition by examining symptoms
- Tips for seamlessly integrating laser therapy into your current treatment regimen to improve patient outcomes and generate practice revenue

Register Here: https://register.gotowebinar.com/register/2673679578332340576?source=social
𝐈𝐆: 𝐋𝐢𝐧𝐤 𝐢𝐧 𝐁𝐢𝐨

01/01/2026

Happy New Year!! We are ready for an exciting and productive year ahead!

12/31/2025

𝐃𝐨𝐞𝐬 𝐩𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐢𝐬 𝐛𝐞𝐭𝐭𝐞𝐫 𝐭𝐡𝐚𝐧 𝐜𝐫𝐲𝐨𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐢𝐧 𝐦𝐮𝐬𝐜𝐥𝐞 𝐫𝐞𝐜𝐨𝐯𝐞𝐫𝐲 𝐚𝐟𝐭𝐞𝐫 𝐚 𝐡𝐢𝐠𝐡-𝐢𝐧𝐭𝐞𝐧𝐬𝐢𝐭𝐲 𝐞𝐱𝐞𝐫𝐜𝐢𝐬𝐞? 𝐀 𝐫𝐚𝐧𝐝𝐨𝐦𝐢𝐳𝐞𝐝, 𝐝𝐨𝐮𝐛𝐥𝐞-𝐛𝐥𝐢𝐧𝐝, 𝐩𝐥𝐚𝐜𝐞𝐛𝐨-𝐜𝐨𝐧𝐭𝐫𝐨𝐥𝐥𝐞𝐝 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐭𝐫𝐢𝐚𝐥
De Marchi, et.al

[...]All subjects performed four sessions at 24-h intervals, during which they submitted to isometric assessment (MVC) and blood collection in the pre-exercise period, and 5 and 60 min post-exercise, while the muscle fatigue induction protocol occurred after the pre-exercise collections. In the remaining sessions performed 24, 48, and 72 h later, only blood collections and MVCs were performed. A single treatment with PBMT and/or cryotherapy was applied after only 2 min of completing the post-5-min MVC test at the first session. In the intragroup comparison, it was found that exercise led to a significant decrease (p < 0.05) in the production of MVC in all groups. Comparing the results of MVCs between groups, we observed significant increases in the MVC capacity of the PBMT, CPG, and PCG volunteers in comparison with both PG and CG (p < 0.05). We observed a significant decrease in the concentrations of the biochemical markers of oxidative damage (TBARS and PC) in all groups and muscle damage (creatine kinase—CK) in the PBMT, PCG, and CPG compared with the PG (p < 0.01). The clinical impact of these findings is clear because they demonstrate that the use of phototherapy is more effective than the use of cryotherapy for muscle recovery, additionally cryotherapy decreases PBMT efficacy.

https://www.researchgate.net/profile/Thiago-Marchi/publication/312079583_Does_photobiomodulation_therapy_is_better_than_cryotherapy_in_muscle_recovery_after_a_high-intensity_exercise_A_randomized_double-blind_placebo-controlled_clinical_trial/links/5ad1414aaca272fdaf77977e/Does-photobiomodulation-therapy-is-better-than-cryotherapy-in-muscle-recovery-after-a-high-intensity-exercise-A-randomized-double-blind-placebo-controlled-clinical-trial.pdf

12/29/2025

𝐄𝐟𝐟𝐞𝐜𝐭𝐬 𝐨𝐟 𝐩𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐲, 𝐩𝐡𝐚𝐫𝐦𝐚𝐜𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐭𝐡𝐞𝐫𝐚𝐩𝐲, 𝐚𝐧𝐝 𝐩𝐡𝐲𝐬𝐢𝐜𝐚𝐥 𝐞𝐱𝐞𝐫𝐜𝐢𝐬𝐞 𝐚𝐬 𝐬𝐢𝐧𝐠𝐥𝐞 𝐚𝐧𝐝/𝐨𝐫 𝐜𝐨𝐦𝐛𝐢𝐧𝐞𝐝 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐨𝐧 𝐭𝐡𝐞 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐫𝐞𝐬𝐩𝐨𝐧𝐬𝐞 𝐢𝐧𝐝𝐮𝐜𝐞𝐝 𝐛𝐲 𝐞𝐱𝐩𝐞𝐫𝐢𝐦𝐞𝐧𝐭𝐚𝐥 𝐨𝐬𝐭𝐞𝐨𝐚𝐫𝐭𝐡𝐫𝐢𝐭𝐢𝐬
Tomazoni, et.al

[...] The present study aimed to evaluate and compare the effects of photobiomodulation therapy (PBMT), physical exercise, and topical nonsteroidal anti-inflammatory drug (NSAID) use on the inflammatory process after they were applied either alone or in different combinations. OA was induced by intra-articular papain injection in the knee of rats. After 21 days, the animals began treatment with a topical NSAID and/or with physical exercise and/or PBMT. Treatments were performed three times a week for eight consecutive weeks, totaling 24 therapy sessions. Analysis of real-time polymerase chain reaction (RT-PCR) gene expression; interleukin (IL)-1β, IL-6, and tumor necrosis factor alpha (TNF-α) protein expression; and PGE2 levels by enzyme-linked immunosorbent assay (ELISA) was conducted. Our results showed that PBMT alone and Exerc + PBMT significantly reduced IL-1β gene expression (p < 0.05) while no treatment changed both IL-6 and TNF-α gene expression. Treatment with NSAID alone, PBMT alone, Exerc + PBMT, and NSAID + PBMT reduced IL-1β protein expression (p < 0.05). All therapies significantly reduced IL-6 and TNF-α protein expression (p < 0.05) compared with the OA group. Similarly, all therapies, except Exerc, reduced the levels of PGE2 (p < 0.05) compared with the OA group. The results from the present study indicate that treatment with PBMT is more effective in modulating the inflammatory process underlying OA when compared with the other therapies tested.

12/26/2025

𝐄𝐟𝐟𝐞𝐜𝐭 𝐨𝐟 𝐥𝐨𝐰-𝐥𝐞𝐯𝐞𝐥 𝐥𝐚𝐬𝐞𝐫 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 (𝐋𝐋𝐋𝐓) 𝐚𝐧𝐝 𝐥𝐢𝐠𝐡𝐭-𝐞𝐦𝐢𝐭𝐭𝐢𝐧𝐠 𝐝𝐢𝐨𝐝𝐞𝐬 (𝐋𝐄𝐃𝐓) 𝐚𝐩𝐩𝐥𝐢𝐞𝐝 𝐝𝐮𝐫𝐢𝐧𝐠 𝐜𝐨𝐦𝐛𝐢𝐧𝐞𝐝 𝐭𝐫𝐚𝐢𝐧𝐢𝐧𝐠 𝐨𝐧 𝐩𝐞𝐫𝐟𝐨𝐫𝐦𝐚𝐧𝐜𝐞 𝐚𝐧𝐝 𝐩𝐨𝐬𝐭-𝐞𝐱𝐞𝐫𝐜𝐢𝐬𝐞 𝐫𝐞𝐜𝐨𝐯𝐞𝐫𝐲: 𝐩𝐫𝐨𝐭𝐨𝐜𝐨𝐥 𝐟𝐨𝐫 𝐚 𝐫𝐚𝐧𝐝𝐨𝐦𝐢𝐳𝐞𝐝 𝐩𝐥𝐚𝐜𝐞𝐛𝐨-𝐜𝐨𝐧𝐭𝐫𝐨𝐥𝐥𝐞𝐝 𝐭𝐫𝐢𝐚𝐥
Aryane Flauzino Machado, et.al

Background
Previous studies have shown positive results of phototherapy for improving performance and accelerating recovery; however, the effects of phototherapy during training and after a primary adaptation remain unclear. The aim of this randomized controlled trial is to analyze the effects of phototherapy and combined training on clinical, functional, and psychological outcomes and on vascular endothelial growth factor.
Methods
This randomized placebo-controlled trial by stratified sample will involve 45 healthy male participants. In phase 1, the participants will undergo six weeks of combined training (sprints and squats). In phase 2, participants will be allocated through stratified randomization (based on adaptation capacity) into three groups: active phototherapy group (AG), placebo group (PG), and non-treatment control group (CG). A new six-week training program will then start and the participants will receive the recovery strategy between sprints and squats. The primary outcome will be maximal isometric contraction. The secondary outcomes include strength and power testing, maximal incremental test, squat jump, sprint test, muscle soreness, pain threshold, perceptions of exertion and recovery, psychological questionnaire, and vascular endothelial growth factor.
Conclusions
This will be the first trial to include phototherapy during training. We believe that this strategy will combine the ergogenic and prophylactic effects in the same session. Furthermore, an application protocol performed after primary adaptation may reflect the real effect of the technique.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5537481/pdf/main.pdf

12/25/2025

Laser Therapy University (LTU) wishes everyone a very happy and safe holiday season. We will return to our normal scheduling post holiday. Have a Happy and Merry!! 🎄☃🎁❄️

12/24/2025

𝐂𝐚𝐧 𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 (𝐏𝐁𝐌𝐓) 𝐌𝐢𝐧𝐢𝐦𝐢𝐳𝐞 𝐄𝐱𝐞𝐫𝐜𝐢𝐬𝐞-𝐈𝐧𝐝𝐮𝐜𝐞𝐝 𝐎𝐱𝐢𝐝𝐚𝐭𝐢𝐯𝐞 𝐒𝐭𝐫𝐞𝐬𝐬? 𝐀 𝐒𝐲𝐬𝐭𝐞𝐦𝐚𝐭𝐢𝐜 𝐑𝐞𝐯𝐢𝐞𝐰 𝐚𝐧𝐝 𝐌𝐞𝐭𝐚-𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬
De Marchi, et.al

[...] To analyze the effects of PBMT about exercise-induced oxidative stress and compare with placebo therapy. Data Sources: Databases such as PubMed, EMBASE, CINAHL, CENTRAL, PeDro, and Virtual Health Library, which include Lilacs, Medline, and SciELO, were searched to find published studies. Study Selection: There was no year or language restriction; randomized clinical trials with healthy subjects that compared the application (before or after exercise) of PBMT to placebo therapy were included. Study Design: Systematic review with meta-analysis. Level of Evidence: 1. Data Extraction: Data on the characteristics of the volunteers, study design, intervention parameters, exercise protocol and oxidative stress biomarkers were extracted. The risk of bias and the certainty of the evidence were assessed using the PEDro scale and the GRADE system, respectively. Results: Eight studies (n = 140 participants) were eligible for this review, with moderate to excellent methodological quality. In particular, PBMT was able to reduce damage to lipids post exercise (SMD = −0.72, CI 95% −1.42 to −0.02, I2 = 77%, p = 0.04) and proteins (SMD = −0.41, CI 95% −0.65 to −0.16, I2 = 0%, p = 0.001) until 72 h and 96 h, respectively. In addition, it increased the activity of SOD enzymes (SMD = 0.54, CI 95% 0.07 to 1.02, I2 = 42%, p = 0.02) post exercise, 48 and 96 h after irradiation. However, PBMT did not increase CAT activity (MD = 0.18 CI 95% −0.56 to 0.91, I2 = 79%, p = 0.64) post exercise. We did not find any difference in TAC or GPx biomarkers. Conclusion: Low to moderate certainty evidence shows that PBMT is a resource that can reduce oxidative damage and increase enzymatic antioxidant activity post exercise. We found evidence to support that one session of PBMT can modulate the redox metabolism.

12/23/2025

𝐇𝐢𝐠𝐡-𝐏𝐨𝐰𝐞𝐫 𝐋𝐚𝐬𝐞𝐫 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐌𝐨𝐝𝐮𝐥𝐚𝐭𝐞𝐬 𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐅𝐮𝐧𝐜𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐑𝐞𝐝𝐨𝐱 𝐁𝐚𝐥𝐚𝐧𝐜𝐞 𝐖𝐢𝐭𝐡𝐨𝐮𝐭 𝐂𝐲𝐭𝐨𝐭𝐨𝐱𝐢𝐜𝐢𝐭𝐲: 𝐀𝐧 𝐈𝐧 𝐕𝐢𝐭𝐫𝐨 𝐒𝐭𝐮𝐝𝐲 𝐢𝐧 𝐁𝐕-𝟐 𝐌𝐢𝐜𝐫𝐨𝐠𝐥𝐢𝐚𝐥 𝐂𝐞𝐥𝐥𝐬
Dias, et.al

Background: Recent technological advances have sparked growing interest in high-power laser devices due to their capacity for energy delivery and therapeutic potential, especially in deeper tissues. This promising approach may be comparable to photobiomodulation for modulating inflammatory and redox processes in various tissues. However, to our knowledge, this is the first study to evaluate the safety profile and redox modulation capacity of high-power laser therapy in BV-2 microglial cells. Methods: This study investigated the cellular responses of BV-2 microglial cells exposed to three laser irradiation protocols using a high-power laser device (650/810/915/980 nm, 657 J total dose), applied at variable distances to simulate in vivo power attenuation. Cell viability, apoptosis, adenosine triphosphate(ATP) levels, mitochondrial membrane potential (MMP), reactive oxygen species (ROS), nitric oxide (NO), and intracellular calcium levels were assessed at multiple time points (5 min to 24 h). Results: Protocol-dependent effects were observed. Protocol A promoted early increases in cell viability and ATP levels, along with decreased apoptotic markers and ROS production, suggesting a protective bioenergetic response. In contrast, Protocol C showed transient increases in oxidative stress and reduced MMP, suggesting possible mitochondrial stress. A selective increase in NO levels under Protocol A also suggests modulation of inflammatory pathways without cytotoxicity. Conclusions: High-power laser therapy modulates redox balance, mitochondrial function, and inflammatory mediators (e.g., NO) in a dual-phase manner in BV-2 microglial cells. These findings contribute to defining safe and effective parameters for potential musculoskeletal and neurological applications.

https://www.mdpi.com/2076-3921/14/10/1243

12/22/2025

𝐄𝐟𝐟𝐞𝐜𝐭𝐬 𝐨𝐟 𝐥𝐨𝐰-𝐥𝐞𝐯𝐞𝐥 𝐥𝐚𝐬𝐞𝐫 𝐩𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝐭𝐡𝐞 𝐦𝐚𝐬𝐭𝐢𝐜𝐚𝐭𝐨𝐫𝐲 𝐟𝐮𝐧𝐜𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐦𝐚𝐧𝐝𝐢𝐛𝐮𝐥𝐚𝐫 𝐦𝐨𝐯𝐞𝐦𝐞𝐧𝐭𝐬 𝐢𝐧 𝐚𝐝𝐮𝐥𝐭𝐬 𝐰𝐢𝐭𝐡 𝐭𝐞𝐦𝐩𝐨𝐫𝐨𝐦𝐚𝐧𝐝𝐢𝐛𝐮𝐥𝐚𝐫 𝐝𝐢𝐬𝐨𝐫𝐝𝐞𝐫: 𝐚 𝐬𝐲𝐬𝐭𝐞𝐦𝐚𝐭𝐢𝐜 𝐫𝐞𝐯𝐢𝐞𝐰 𝐰𝐢𝐭𝐡 𝐦𝐞𝐭𝐚-𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬
Camila Fonsêca Guedes Pereira Máximo , et.al

Purpose
To review the effects of low-level laser photobiomodulation on masticatory function and mandibular movements in adults with temporomandibular disorder.
Research strategies
Search in PubMed, Web of Science, Scopus, EMBASE, Cochrane, LILACS, ScienceDirect, and Google Scholar, using the following descriptors: “temporomandibular joint disorders”, “low-level light therapy”, “low-level laser therapy”, “mastication”, and “mandible”.
Selection criteria
Randomized clinical trials in adults with temporomandibular disorder, using low-level laser and assessing the mastication and mandibular movements.
Data analysis
Firstly, the titles and abstracts of all retrieved studies were read. Then, only the studies selected in the first stage were read in full and assessed regarding eligibility. After the selection, the characteristics, methodological quality, and quality of evidence of the studies included in the review were analyzed. In the meta-analysis, the mean amplitude of mouth opening was considered as a measure of intervention effect.
Results
The 10 articles included in the review had quite different results one from the other, especially regarding the amplitude of mouth opening, while the mastication was assessed in only one of them. Most studies had a high risk of bias, demonstrating a low methodological quality. Significantly higher results for photobiomodulation were identified in the six studies included in the meta-analysis.
Conclusion
Due to the scarcity in the literature, there is not enough evidence of the effects of low-level laser photobiomodulation on mastication. As for the mandibular movements, this intervention presented significant results, particularly in the amplitude of mouth opening.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9769431/

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