Cerebral Amyloid Angiopathy

Cerebral Amyloid Angiopathy This page is intended as a resource for patients and families living with Cerebral Amyloid Angiopathy A macrobleed is the bleeding (hemorrhagic) form of stroke.

DISCLOSURE: THIS PAGE IS NOT MEANT TO BE A CLINICAL RESOURCE. FOR CLINICAL QUESTIONS ABOUT CAA, PLEASE CONTACT YOUR DOCTOR. Cerebral Amyloid Angiopathy (CAA) is a neurological disease defined by a type of protein deposit in the wall of blood vessels in the brain. CAA is actually a common process in aging and is usually harmless. In some people with severe CAA, however, the protein deposits cause t

he blood vessel walls to crack, in which case blood can leak out and damage the brain. Damage from this process are called brain bleeds, and can either be small (microbleeds) or large (macrobleeds). This page is intended to be a centralized space for individuals living with CAA, their friends, family, and others interested in the disease to share CAA-related news, resources, and to connect with one another. This page is hosted by the Cerebral Amyloid Angiopathy and Hemorrhagic Stroke research group at the Massachusetts General Hospital. Initiated in 1994, the Hemorrhagic Stroke Research Program has become internationally recognized as a leading authority on the causes, diagnosis, and treatment of cerebral amyloid angiopathy.

Everyday habits can play a role in brain health. Share below what you find helpful!
04/15/2026

Everyday habits can play a role in brain health. Share below what you find helpful!

Taking care of our brains can look like small, everyday moments - reading, learning, staying engaged. 🩵This article shar...
04/08/2026

Taking care of our brains can look like small, everyday moments - reading, learning, staying engaged. 🩵

This article shares more on how mental activity may support long-term brain health!

People who spent more time in mentally passive activities while sitting had a significantly higher risk of developing dementia later, according to a new study.

Our newest edition of Pathways to a Cure, The Cerebral Amyloid Angiopathy Newsletter is now live! This edition provides ...
03/31/2026

Our newest edition of Pathways to a Cure, The Cerebral Amyloid Angiopathy Newsletter is now live!

This edition provides an update on the recently completed Vasomotion study, as well as an update on the cAPPricorn-1 trial.

All previous editions are also available on our website!

Check it out below:

https://www.angiopathy.org/pathways-to-a-cure?fbclid=IwY2xjawQ5DC9leHRuA2FlbQIxMQBzcnRjBmFwcF9pZBAyMjIwMzkxNzg4MjAwODkyAAEe73NSqzZKiBwraO_ApXu6SnfqtMkpEBsrFJ2lAqJ4GT4Eb2oDCp8XmOYxO0w_aem_K874gsyUT63X_vyjW-rkZg

Pathways to a Cure is a research newsletter developed and published by Dr. Steven Greenberg’s CAA Research Team at the Massachusetts General Hospital Stroke Research Center.

CAA can look very different from person to person.For some, there may be no symptoms at all!
03/25/2026

CAA can look very different from person to person.

For some, there may be no symptoms at all!

Have you ever seen the word “microbleeds” on a report and wondered what it actually meant?Here’s a simple breakdown.
03/04/2026

Have you ever seen the word “microbleeds” on a report and wondered what it actually meant?

Here’s a simple breakdown.

Check out this great activity from the American Heart Association!We hope everyone is staying safe and healthy. 🩵
02/25/2026

Check out this great activity from the American Heart Association!

We hope everyone is staying safe and healthy. 🩵

Myth vs. Fact!Not all stroke-like symptoms in CAA are strokes.
02/18/2026

Myth vs. Fact!

Not all stroke-like symptoms in CAA are strokes.

Learning about CAA can feel overwhelming.This page of frequently asked questions is a great place to start!
02/11/2026

Learning about CAA can feel overwhelming.

This page of frequently asked questions is a great place to start!

Frequently Asked Questions *DISCLAIMER: The content of this website is for informational purposes only. Always seek the advice of your physician or other qualified health care provider with any questions you may have. By using this Website you hereby consent to the disclaimer and agree to its terms....

Ever wondered what the difference between CAA and CAA-ri (CAA-related inflammation) is? Here’s a quick breakdown.
01/28/2026

Ever wondered what the difference between CAA and CAA-ri (CAA-related inflammation) is?

Here’s a quick breakdown.

From the American Stroke Association — a little love for all the caregivers in our CAA community. You’re amazing!
11/26/2025

From the American Stroke Association — a little love for all the caregivers in our CAA community. You’re amazing!

Being a caregiver is one of the most rewarding and challenging jobs. We appreciate you more than you know!

Return of the CAA factoids! See below to learn more about the relationship between blood pressure and CAA.
11/19/2025

Return of the CAA factoids! See below to learn more about the relationship between blood pressure and CAA.

Repost from Mass General Brigham Research on LinkedIn:Think that extra drink won’t hurt? Your brain might disagree.A new...
11/12/2025

Repost from Mass General Brigham Research on LinkedIn:

Think that extra drink won’t hurt? Your brain might disagree.

A new study found that among patients admitted to Massachusetts General Hospital with a brain bleed, those who drank three or more alcoholic drinks a day had larger, deeper brain bleeds at a younger age and more signs of small-vessel and blood-pressure-related brain damage.

“The brain bleed is one of the most lethal and disabling conditions known to human beings,” said author Edip Gurol, MD. “They come on suddenly, cause severe damage, and often leave patients with life-changing disabilities. It’s one of the most difficult conditions to recover from.”

The researchers hypothesize that heavy alcohol use raises blood pressure, damaging the small blood vessels in the brain, making them weak and more likely to leak or burst. On top of that, lowered platelet counts make it harder for the body to stop bleeding. Together, these factors greatly increase the risk of a brain bleed.

Read the full article here: https://www.massgeneralbrigham.org/en/about/newsroom/press-releases/heavy-alcohol-use-linked-to-brain-bleed-risk

LinkedIn post: https://www.linkedin.com/posts/mgbresearch_think-that-extra-drink-wont-hurt-your-brain-activity-7392194265294073856-PduZ?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAHUjDgBOeCf0o01Izaw5WbskNc--vLXrjQ

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