11/21/2025
Hereās what this study found:
Hormonal contraceptive pills (āThe Pillā) were associated with a slightly increased relative risk of breast cancer. But hereās the part nobody is talking about:
ā”ļø Progestin-only pills carried a higher risk than combined oral contraceptives (estrogen/ progestin pills)
And the addition of estrogen actually decreased risk. Which means estrogen attenuated the breast cancer signal from synthetic progestins. And this was dose dependent, with the higher doses of estrogen carrying the lower risk. š
This aligns with what we learned from the Womenās Health Initiative reanalysis. Estrogen is not the villain. Synthetic progestins might be more problematic. (Note: this does NOT mean progesterone is the problem, as micronized progesterone is different than synthetic progestins)
And just to put this in perspective:
This was a 24% relative increase risk, but the absolute risk of breast cancer was still very small⦠About 1 extra case per ~7,700 users per year.
All this to sayā¦
š We need a more nuanced conversation about contraception and risk.
š Birth control pills are not the best treatment for perimenopause symptoms (the risks outweigh the benefits in most women).
š We have been worried about the wrong thing here, and need to stop reflexively blaming estrogen for everything.
Thoughts on this topic? Drop them below and share this post so more women can get the information they need to make more informed decisions about their health.