12/18/2025
Did you know that perimenopause can deplete your NAD+ levels? As estrogen drops, so does this critical molecule, leading to the "big three" symptoms: energy crashes, brain fog, and mood swings. Since NAD+ is vital for DNA repair and cellular energy, low levels can make the transition to menopause feel much harder. Boosting your NAD+ through lifestyle changes or precursors can help:
⬇️Why NAD+ Levels Drop in Perimenopause:
⬇️Hormonal Decline: Falling estrogen levels directly correlate with a rapid decrease in NAD+.
🕗Cellular Aging: Lower NAD+ accelerates the aging process at a cellular level.
🧭 Hormone Pathways: NAD+ supports metabolic and hormonal pathways, so declining levels disrupt estrogen, progesterone, and testosterone regulation.
Symptoms of Low NAD+ Levels During Perimenopause:
👇Suddenly, crashing fatigue
🧠Brain fog, forgetfulness, and difficulty concentrating
🧟 Irritability, anxiety and mood swings
🤦Afternoon energy crashes
🙍♀️Difficulty with motivation of feeling overwhelmed constantly
😴Poor sleep quality, including night sweats
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