STOP T1D

03/19/2026

AID systems users who don't relocate their infusion sites as recommended may be at risk for hyperglycemia and ketosis.

"Commenting on the issue, Satish K. Garg, MD, a professor of medicine and pediatrics and director of the Adult Program at the Barbara Davis Center for Diabetes, University of Colorado Anschutz, in Aurora, Colorado, said that in his experience, insulin pump occlusion cases are not at all uncommon."

“'Whenever I am on call, the only significant calls that I get are early hyperglycemia and ketosis due to pump catheter occlusions.'" -- Satish K. Garg, MD

Read: Frequent Insulin Infusion Site Failures ‘a Huge Problem’ https://www.medscape.com/viewarticle/frequent-insulin-infusion-site-failures-huge-problem-2026a10008a9

Unexplained hyperglycemic events may be due to undetected occlusions, a common problem that experts say needs to be addressed through education and technology.

03/18/2026

It turns out that when CGMs are made easier and more affordable to acquire, most people managing will gladly use them and their glucose management improves.

"CGM use increased from 29.4% to 76.2% over the study duration, and uptake increased in all sociodemographic groups likely due to universal subsidisation."

Diabetic Medicine | Diabetes UK Journal | Wiley Online Library https://onlinelibrary.wiley.com/doi/10.1111/dme.70261

Aims The availability of diabetes technologies has increased, although access can be limited for young people with type 1 diabetes (T1D). In Australia, access to subsidised continuous glucose monito...

03/17/2026

TOMORROW! Wednesday, March 18 at Noon MDT/ 2 PM EDT > Ask the Experts Office Hours, hosted by the Ask the Experts Team from the Barbara Davis Center for Diabetes.

We will discuss early cases you may have questions about. Attendees will also have the opportunity to ask general questions related to early screening and follow-up monitoring. We look forward to your attendance and participation!

✅ REGISTER to Join: https://www.asktheexperts.org/office-hours-mar18

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Ask the Experts and this Office Hours program is supported by The Leona M. and Harry B. Helmsley Charitable Trust.

Registration Form for our monthly "Office Hours" Zoom call for HCPs — to discuss early T1D questions and cases.

03/16/2026

‼️ Health Care Providers! Advance your knowledge and awareness while earning credits for a course developed by top U.S. research physicians at the Barbara Davis Center for Diabetes (BarbaraDavisCenter.org).

STOPT1Dprogram.org offers free credits for , , and professionals through online learning that can be accessed any time it's convenient for you from your desktop browser or mobile device.

Take the program modules at your own pace. Most people complete them in a couple of hours. The T1D course covers:

⭐️ T1D Screening methods and confirmation
⭐️ Target populations
⭐️ Communication of results
⭐️ Patient monitoring
⭐️ Available intervention and clinical trial opportunities
⭐️ Implementation of screening and monitoring into health systems

please visit https://www.stopt1dprogram.org/for-hcp to review the program.

You can take the course for FREE through freeCME here: https://www.freecme.com/products/stop-t1d-screen-to-prevent-type-1-diabetes

Welcome to STOP T1D — Screen TO Prevent Type 1 Diabetes — an educational program for health care providers. Individuals/families who have screened positive for T1D autoantibodies may join the STOP T1D Registry, and find helpful LINKS to other T1D resources.

03/12/2026

The research physicians at Barbara Davis Center for Diabetes studied the effects teplizumab has on treating Stage 2 . Study results are available to review online now!

"This study provides the first real-world evidence that teplizumab can be safely and effectively administered in clinical practice, with early metabolic and immunological benefits in individuals with stage 2 type 1 diabetes. Treatment improved glucose tolerance, stabilised HbA1c and C-peptide, and introduced CGM as a real-world metric to assess glycaemic changes after treatment."

Teplizumab treatment for stage 2 type 1 diabetes: a real-world evaluation of metabolic and immunological outcomes - Diabetologia https://link.springer.com/article/10.1007/s00125-025-06646-6

Aims/hypothesis This is the first real-world prospective observational study of teplizumab use following approval by the United States Food and Drug Administration in individuals with stage 2 type 1 diabetes. We examined whether glycaemic responses observed in controlled trials were reproduced in re...

03/11/2026

New in : The British Medical Association (BMA) concludes from research on possible inflammatory effects of diabetic ketoacidosis (DKA) in children, "DKA causes a unique inflammatory pattern distinct from inflammatory changes in acute hyperglycemia or T1D-related autoimmunity. Alterations in MMPs and their tissue inhibitors play a dominant role in this inflammatory profile."

Further, "New-onset diabetes without DKA (within 24 hours of initiating insulin treatment) involved fewer inflammatory alterations, being characterized only by changes in MMP-2 and MMP-9. These changes were no longer present several days after beginning insulin treatment, suggesting that changes in MMP-2 and MMP-9 are likely stimulated by hyperglycemia or low insulin levels. Further studies are needed to investigate associations between the inflammatory response to DKA and clinical patterns of organ injury."

Read: "Inflammatory profile of diabetic ketoacidosis in children with type 1 diabetes" > https://drc.bmj.com/content/14/2/e004961

03/10/2026

👉 Coming up on Wednesday, March 18 at Noon MDT/ 2 PM EDT > Ask the Experts Office Hours, hosted by the Ask the Experts Team from the Barbara Davis Center for Diabetes.

🔷 Please come prepared to discuss early cases you may have questions about. Attendees will also have the opportunity to ask general questions related to early screening and follow-up monitoring.

💙 We look forward to your attendance and participation!

👉 REGISTER to Join: https://www.asktheexperts.org/office-hours-mar18

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Ask the Experts and this Office Hours program is supported by The Leona M. and Harry B. Helmsley Charitable Trust.

Registration Form for our monthly "Office Hours" Zoom call for HCPs — to discuss early T1D questions and cases.

03/06/2026

New in out of the Netherlands: "'Over 6 months, the urinary albumin-to-creatinine ratio (UACR) decreased by 34% in participants on finerenone compared with 12% in those on placebo (geometric mean ratio 0.75, 95% CI 0.65-0.87, P

First new drug in 30 years to slow kidney disease in type 1 diabetes

03/05/2026

The development of the drug Teplizumab (Tzield) has been a turning point for delaying Stage 3 onset.

Read more about what we've learned since it's emergence in 2022 as a treatment: "Changing the Course of Type 1 Diabetes - Breakthrough T1D " > https://www.breakthrought1d.org/news-and-updates/changing-type-1-diabetes/

Tzield is the first approved disease-modifying therapy for type 1 diabetes. Breakthrough T1D is working to make sure it’s not the last.

03/05/2026

Happening tomorrow, March 5 at noon ET online! > Saliva-based At-home GRS Testing for Scalable and Accessible T1D Screening https://thesugarscience.substack.com/p/saliva-based-at-home-grs-testing

Ahead of tomorrow's talk by Yuta Matsuda PhD

03/03/2026

Fasting for Ramadan? Here are recent findings out of Saudi Arabia that indicate managing using an automated insulin delivery system ( ) while fasting results in better glycemic control, thereby reducing the risk of hypoglycemia.

"Use of AID during Ramadan fasting was associated with fasting the most days of Ramadan, best glycemic control, and the least frequent hypoglycemia avoidance behaviors. The International Diabetes Federation/Diabetes and Ramadan International Alliance risk calculator should consider a lower risk score for AID technology when used by PWT1D."

Insulin delivery modality and fasting interruption, glycemic control, and fear of hypoglycemia in type 1 diabetes: a prospective, multicenter study from Saudi Arabia https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(26)00115-4/abstract

Most people with type 1 diabetes (PWT1D) typically avoid fasting during Ramadan because of dysglycemia risks. We compared efficacy, safety profiles, and fear of hypoglycemia (FOH) during Ramadan fasting in users of four insulin delivery modalities.

03/02/2026

✅ Ask the Experts Office Hours Resumes March 18, 2026. Hosted by the Ask the Experts Team from the Barbara Davis Center for Diabetes and STOP T1D

This 1-Hour Zoom-session will be held on:
Wednesday March 18, 2026
NOON (MST) / 2 PM (EST)

Please come prepared to discuss early cases you may have questions about. Attendees will also have the opportunity to ask general questions related to early screening and follow-up monitoring.

We look forward to your attendance and participation!

REGISTER to Join: https://www.asktheexperts.org/office-hours-mar18

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Ask the Experts and this Office Hours program is supported by The Leona M. and Harry B. Helmsley Charitable Trust.

Registration Form for our monthly "Office Hours" Zoom call for HCPs — to discuss early T1D questions and cases.