24/08/2020
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Does CBD oil work for chronic pain management?
Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT — Written by Jon Johnson on September 20, 2017
Effects
What is CBD oil?
Benefits for pain treatment
Other uses
Dosage
Side effects
Other considerations
Takeaway
While many people use cannabidiol to relieve pain, more scientific research is needed to be sure it is safe. Understanding cannabidiol can help overcome the stigma associated with it.
Some people experience side effects when taking cannabidiol (CBD) and there are other factors to consider before using CBD oil for pain.
In this article, we look at how CBD oil works and how people can use it to relieve chronic pain.
Effects
More research is necessary to confirm that CBD is a safe option for relieving pain.
CBD is one of more than 120 compounds called cannabinoids.
Many plants contain cannabinoids, but people most commonly link them to cannabis.
Unlike other cannabinoids — such as tetrahydrocannabinol (THC) — CBD does not produce a euphoric “high” or psychoactive effect. This is because CBD does not affect the same receptors as THC.
The human body has an endocannabinoid system (ECS) that receives and translates signals from cannabinoids. It produces some cannabinoids of its own, which are called endocannabinoids. The ECS helps to regulate functions such as sleep, immune-system responses, and pain.
When THC enters the body, it produces a “high” feeling by affecting the brain’s endocannabinoid receptors. This activates the brain’s reward system, producing pleasure chemicals such as dopamine.
Does CBD make you high?
CBD is an entirely different compound from THC, and its effects are very complex. It is not psychoactive, meaning it does not produce a “high” or change a person’s state of mind, but it influences the body to use its own endocannabinoids more effectively.
According to one study posted to Neurotherapeutics, this is because CBD itself does very little to the ECS. Instead, it activates or inhibits other compounds in the endocannabinoid system.
For example, CBD stops the body from absorbing anandamide, a compound associated with regulating pain. So, increased levels of anandamide in the bloodstream may reduce the amount of pain a person feels.
Cannabidiol may also limit inflammation in the brain and nervous system, which may benefit people experiencing pain, insomnia, and certain immune-system responses.
-- Medical News Today
