02/06/2026
New national data highlight the long-term outcomes of orthostatic hypotension (OH) in Parkinson’s disease, with important implications for fall risk and cardiovascular safety.
“In a nationwide cohort of 111,368 patients with Parkinson’s disease, orthostatic hypotension (OH) was associated with higher 5-year fall risk (31.7% vs 23.4%; adjusted OR 1.35), but not with major cardiovascular events (adjusted OR 0.99). Among patients with OH, pharmacotherapy was associated with increased fall risk (adjusted OR 1.34), while no significant association with cardiovascular events was observed.” — Hikaru Kamo, M.D., Ph.D.
Read the full study: https://www.sciencedirect.com/science/article/pii/S135380202600043X