Dennis R. Holmes M.D., F.A.C.S.

Dennis R. Holmes M.D., F.A.C.S. Breast Cancer Surgery specializing in minimally invasive procedures to reduce the burden on breast cancer treatment. Dennis R. Holmes, M.D.

Find out more at www.drholmesmd.com or www.cryoablation.com is an internationally renowned breast cancer, surgeon, surgeon educator, and cancer researcher specializing in the management of breast cancer. Dr. Holmes is medical director of the Sam and Grace Carvajal Comprehensive Breast Center at Adventist Health Glendale in Los Angeles, CA. He is also Co-Founder and CEO of XpediteMD, Inc., a digital health technology company working to improve the efficiency, quality, and value of cancer care. Dr. Holmes completed his medical education at Tulane University School of Medicine, surgical residency in general surgery at the University of San Francisco, and a fellowship in breast surgery at the University of Southern California. Dr. Holmes is a board-certified Fellow of the American College of Surgeons and recently served as Program Chair of the 20th Annual National Meeting of the American Society of Breast Surgeons and is the 2023 Health Policy Scholar for the American College of Surgeons. He has also served as department head of several academic breast cancer programs and program director of two breast surgery fellowship programs. His has also played a pivotal role in several breast cancer treatment innovations, including intraoperative radiotherapy, oncoplastic surgery, and cryoablation.

Cryoablation, a minimally invasive procedure, offers another unexpected benefit which is fewer disruptions to hormone th...
12/29/2025

Cryoablation, a minimally invasive procedure, offers another unexpected benefit which is fewer disruptions to hormone therapy.

Traditional treatments can sometimes delay or complicate ongoing care plans. With Cryoablation, many women can continue hormone therapy without pause, allowing their overall treatment plan to stay on track and aligned with their goals.

It’s a thoughtful approach, made possible by the precision and minimal recovery time of Cryoablation.
❄️📅🧬

https://www.cryoablation.com/

There are moments in this work that remind us exactly why we do what we do. C.J.’s words speak to the power of timely, p...
12/26/2025

There are moments in this work that remind us exactly why we do what we do. C.J.’s words speak to the power of timely, personalized care and the importance of feeling genuinely supported. Cryoablation, a minimally invasive treatment, made it possible for her to undergo the procedure without delay, on her terms, and without compromising expert attention.

To every patient who places their trust in us, we’re honored to walk this path with you.❄️🩺

https://www.cryoablation.com/

A question we often receive is, “What does Cryoablation feel like?”Cryoablation, a minimally invasive procedure, uses ex...
12/24/2025

A question we often receive is, “What does Cryoablation feel like?”

Cryoablation, a minimally invasive procedure, uses extreme cold to treat cancerous tissue, but it’s not designed to cause significant pain. Many patients report minimal discomfort during the procedure, and because there’s no major incision or tissue removal, recovery tends to be gentler than traditional approaches.

Post-procedure soreness is usually mild and temporary, and in most cases, over-the-counter medication is all that’s needed.

We’re here to make sure you feel informed and supported at every step of the way!❄️🧊

The holidays can bring so many emotions such as joy, reflection, overwhelm, and gratitude. If you or someone you love is...
12/22/2025

The holidays can bring so many emotions such as joy, reflection, overwhelm, and gratitude. If you or someone you love is facing a breast cancer diagnosis this season, we want you to know there are options, and you don’t have to navigate them alone.

Cryoablation, a minimally invasive procedure, offers a treatment path that protects your time, your body, and your peace of mind. There is no hospital stay, no stitches, just compassionate care that fits into your life.

If you’ve recently received a diagnosis or want to explore your options, we’re here to help.❄️🎄🤍

https://www.cryoablation.com/

The precision of Cryoablation, a minimally invasive procedure, hinges on the power of advanced imaging. Radiologic guida...
12/20/2025

The precision of Cryoablation, a minimally invasive procedure, hinges on the power of advanced imaging. Radiologic guidance ensures accuracy at every phase, from targeting the tumor to confirming treatment response.

We collaborate with radiologists who specialize in interpreting these scans and understand the nuances of post-Cryoablation imaging. Their expertise helps protect outcomes and gives patients confidence in every step of care.❄️🖥️🔍

https://www.cryoablation.com/

Exploring Cryoablation, a minimally invasive procedure, as part of a clinical trial offers a unique opportunity for elig...
12/18/2025

Exploring Cryoablation, a minimally invasive procedure, as part of a clinical trial offers a unique opportunity for eligible patients to access advanced treatment while contributing to the future of breast cancer care.

Our team carefully reviews imaging, diagnosis, and medical history to determine who may qualify. If you’re curious about what participation could look like or want to learn more about current research efforts, we’re here to answer your questions!❄️🩺🔬

https://www.cryoablation.com/

Back to Movement, back to you after breast cancer treatment.One of the most immediate benefits women notice after Cryoab...
12/16/2025

Back to Movement, back to you after breast cancer treatment.

One of the most immediate benefits women notice after Cryoablation, a minimally invasive treatment, is how quickly they’re able to resume normal activity.

With no stitches, no drains, and only a tiny incision, recovery is often faster and gentler than they expected. Many return to daily routines, and even light exercise, within days.💪👟✨

https://www.cryoablation.com/

One of the often-overlooked benefits of Cryoablation, a minimally invasive procedure, is how quickly patients are able t...
12/14/2025

One of the often-overlooked benefits of Cryoablation, a minimally invasive procedure, is how quickly patients are able to return to physical activity.

There’s no hospital stay, no general anesthesia, and no extended downtime. For many women, that means being able to lift their arms comfortably, get dressed without restriction, and resume daily routines, including fitness, sooner than they expected.

The ability to move freely again is more than a milestone, it is a reminder that healing doesn’t always have to mean putting your life on hold.🩹💪🧘‍♀️

https://www.cryoablation.com/

For many women, breast cancer brings fears beyond the diagnosis such as fears about intimacy, confidence, and connection...
12/12/2025

For many women, breast cancer brings fears beyond the diagnosis such as fears about intimacy, confidence, and connection. Cryoablation, a minimally invasive procedure, preserves the shape and sensitivity of the breast, which can make a meaningful difference in how women feel in their bodies and in their relationships.

If you’re exploring treatment options, our team is here to walk you through what Cryoablation can offer in your specific case.🙌✨

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, lets many women return to their lives without the markers of traditional t...
12/10/2025

Cryoablation, a minimally invasive procedure, lets many women return to their lives without the markers of traditional treatment. There is no hospital stay and no prolonged recovery.

For those who prefer privacy, simplicity, and autonomy, it’s an option that respects how you want to move through care.❄️💗

https://www.cryoablation.com/

Updates on Cryoablation--2024 Year in Review by Dr. Holmes-FDA clearance-FROST Trial Update-DCIS Cryoablation Trial Upda...
12/09/2025

Updates on Cryoablation--2024 Year in Review by Dr. Holmes

-FDA clearance
-FROST Trial Update
-DCIS Cryoablation Trial Update
-Upcoming Book, "Freeze Away Breast Cancer"

Email from Dennis R. Holmes, MD, FACS     L.A. Breast Chronicles December 7, 2025 By Dennis R. Holmes, MD, F.A.C.S. 2025 Year in Review  As we approach the end of 2025, I am pleased to provide a br

Cryoablation may still be a viable option when a new tumor develops in the same or opposite breast. Every case is differ...
12/08/2025

Cryoablation may still be a viable option when a new tumor develops in the same or opposite breast. Every case is different and that’s where careful assessment matters. Before recommending treatment, we evaluate recurrence patterns, imaging reports, and pathology findings to determine how Cryoablation, a minimally invasive procedure, may fit into your long-term plan.

This isn’t a one-size-fits-all approach. It’s personalized medicine that considers your full history, your goals, and the evolving science behind tumor control and tissue preservation.📚🔍

https://www.cryoablation.com/

Address

Glendale, CA

Opening Hours

Wednesday 9am - 5pm
Thursday 9am - 5pm

Telephone

+18002035515

Website

http://www.cryoablation.com/

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