Dennis R. Holmes M.D., F.A.C.S.

Dennis R. Holmes M.D., F.A.C.S. Breast Cancer Surgery specializing in minimally invasive procedures to reduce the burden on breast cancer treatment. Dennis R. Holmes, M.D.

Find out more at www.drholmesmd.com or www.cryoablation.com is an internationally renowned breast cancer, surgeon, surgeon educator, and cancer researcher specializing in the management of breast cancer. Dr. Holmes is medical director of the Sam and Grace Carvajal Comprehensive Breast Center at Adventist Health Glendale in Los Angeles, CA. He is also Co-Founder and CEO of XpediteMD, Inc., a digital health technology company working to improve the efficiency, quality, and value of cancer care. Dr. Holmes completed his medical education at Tulane University School of Medicine, surgical residency in general surgery at the University of San Francisco, and a fellowship in breast surgery at the University of Southern California. Dr. Holmes is a board-certified Fellow of the American College of Surgeons and recently served as Program Chair of the 20th Annual National Meeting of the American Society of Breast Surgeons and is the 2023 Health Policy Scholar for the American College of Surgeons. He has also served as department head of several academic breast cancer programs and program director of two breast surgery fellowship programs. His has also played a pivotal role in several breast cancer treatment innovations, including intraoperative radiotherapy, oncoplastic surgery, and cryoablation.

Cryoablation is a gentle, minimally invasive option for breast cancer treatment. This procedure uses a Cryoprobe to deli...
01/19/2026

Cryoablation is a gentle, minimally invasive option for breast cancer treatment. This procedure uses a Cryoprobe to deliver extremely cold temperatures directly to the tumor under imaging guidance. Liquid nitrogen flows through the probe, creating an ice ball that freezes and destroys the cancer cells while sparing healthy tissue nearby.

This precise freeze–thaw cycle is carefully planned and monitored to be both effective and gentle, preserving the natural shape of the breast without general anesthesia or a hospital stay.

If you’ve been diagnosed and want to understand all your options, connect with us to see if Cryoablation may be right for you.📍💬

https://www.cryoablation.com/

The recent FDA approval of the ProSense cryoprobe for breast cancer Cryoablation is an important development in expandin...
01/17/2026

The recent FDA approval of the ProSense cryoprobe for breast cancer Cryoablation is an important development in expanding treatment options for qualifying patients. This approval currently applies to women aged 70 and older with low-risk, hormone-sensitive, HER2/neu-negative invasive ductal carcinoma measuring 1.5 cm or less.

Although coverage is limited to hospital-based settings and only includes the technical cost, ongoing studies and future billing code updates aim to increase access and reimbursement across more settings. We’re proud to contribute to this next phase of data collection and care.

Every step matters, and we’re walking it with purpose.
💙📋🩺

https://www.cryoablation.com/

The impact of breast cancer doesn’t end with treatment. For many women, it touches every part of how they feel in their ...
01/15/2026

The impact of breast cancer doesn’t end with treatment. For many women, it touches every part of how they feel in their body and in their relationships. Intimacy can feel uncertain, especially when there are changes to appearance or sensation.

Cryoablation offers an approach that helps preserve the natural shape and appearance of the breast, with minimal disruption to how you look or feel in your skin. That can make a real difference in how women experience closeness and navigate relationships during recovery.

Protecting your body doesn’t mean disconnecting from it. For many women, this treatment path helps preserve a deeper sense of self, one that includes softness, strength, and the freedom to stay present with the people they love. 🤍🌿

https://www.cryoablation.com/

Choosing Cryoablation doesn’t mean starting over with a new medical team, it means building on the care you already trus...
01/13/2026

Choosing Cryoablation doesn’t mean starting over with a new medical team, it means building on the care you already trust. We believe that coordinated, compassionate care makes all the difference, which is why we stay in close communication with your existing providers every step of the way.

🤝 We coordinate directly with your oncologist to ensure Cryoablation aligns with your overall treatment plan.

🩺 We stay in touch with your breast surgeon if one is involved, so that options remain open and fully informed.

📋 We loop in your primary care provider to keep them updated and involved in your follow-up and wellness care.

Collaboration is at the heart of what we do. You deserve a care plan that’s personalized, comprehensive, and connected.

https://www.cryoablation.com/

When you’re facing a breast cancer diagnosis, the last thing you want is to feel like life has to come to a complete hal...
01/11/2026

When you’re facing a breast cancer diagnosis, the last thing you want is to feel like life has to come to a complete halt. Cryoablation offers an option that not only treats the cancer, it also respects your time, your routine, and your sense of self.

Most women are cleared to return to their usual physical activity within just a few days, including walking, getting back to everyday movement, and LIGHT working out. There are no stitches to monitor, no surgical drains to manage, and most patients experience only mild soreness at the treatment site.

That kind of gentle recovery matters. It means you can continue doing the things that bring you strength, whether that is being present with family, staying active, or simply maintaining a sense of normalcy. You shouldn’t have to choose between care and living your life. Cryoablation gives many women the ability to do both.❄️💕

For the right tumors, Cryoablation can be an exceptionally effective option.This minimally invasive treatment is best su...
01/09/2026

For the right tumors, Cryoablation can be an exceptionally effective option.

This minimally invasive treatment is best suited for tumors that are small (typically under 1.5 cm), low-grade, estrogen-receptor-positive (ER+), and most often found in postmenopausal women. When these criteria are met, the data is compelling, success rates are high, recurrence rates are low, and most patients report high satisfaction with both the experience and the outcome.

That said, patient selection is key. We don’t offer a one-size-fits-all recommendation. Each case is reviewed with care, taking into account tumor biology, breast density, and individual preferences. Our goal is always to help you make an informed decision with a clear understanding of the benefits and limitations of every option available.🔬🩺📊

https://www.cryoablation.com/

When you’re facing a breast cancer diagnosis, having a surgeon who truly listens, and offers a treatment plan tailored t...
01/07/2026

When you’re facing a breast cancer diagnosis, having a surgeon who truly listens, and offers a treatment plan tailored to you, can make all the difference.

Cryoablation, a minimally invasive treatment, works by freezing and destroying tumors with precision. There’s no surgery, no stitches, and for many women, a whole lot of relief. These stories are a powerful reminder of why we do what we do.

To every patient and family who’s trusted us in their care, thank you.🤍💬

https://www.cryoablation.com/

When women reach out to us, they’re often navigating more than just a diagnosis. They’re balancing families, careers, an...
01/05/2026

When women reach out to us, they’re often navigating more than just a diagnosis. They’re balancing families, careers, and day-to-day responsibilities, and they’re looking for a treatment option that doesn’t ask them to pause everything in order to move forward.

With no stitches, no drains, and minimal disruption to the body, many women are able to return to their routines quickly, often within a day or two. What truly stands out is the sense of control it gives back. For those who want care that fits into their lives, Cryoablation can be a powerful choice.❄️🌅✨

https://www.cryoablation.com/

Cryoablation begins and ends with precision, and that precision starts with imaging. Ultrasound, mammogram, and MRI view...
01/05/2026

Cryoablation begins and ends with precision, and that precision starts with imaging. Ultrasound, mammogram, and MRI views guide every stage of care, from diagnosis and probe placement to post-treatment follow-up.

This real-time visualization allows us to treat the exact area needed while preserving surrounding tissue. We specialize in breast imaging and know exactly what to watch for at every step. 🎯🖥️🔍

https://www.cryoablation.com/

Cryoablation requires only one tiny incision, no stitches, no drains, and no limitations with bulky bandages or restrict...
01/03/2026

Cryoablation requires only one tiny incision, no stitches, no drains, and no limitations with bulky bandages or restricted arm movement. Many women are relieved to discover how quickly they’re able to lift their arms and return to daily routines. It is a reminder that care doesn’t have to come at the cost of comfort.🧊🩹✨

You shouldn’t have to choose between effective breast cancer treatment and protecting your time, comfort, and sense of s...
01/02/2026

You shouldn’t have to choose between effective breast cancer treatment and protecting your time, comfort, and sense of self.

Cryoablation, a minimally invasive treatment, gives many women the option to pursue care without putting their entire lives on hold. The procedure typically takes under an hour and requires only local anesthesia. Most women return to their normal routines quickly, with little disruption, no hospital stay, and no need for extended downtime.

It’s care that fits into real life, not the other way around.
🙌✨

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, offers another unexpected benefit which is fewer disruptions to hormone th...
12/29/2025

Cryoablation, a minimally invasive procedure, offers another unexpected benefit which is fewer disruptions to hormone therapy.

Traditional treatments can sometimes delay or complicate ongoing care plans. With Cryoablation, many women can continue hormone therapy without pause, allowing their overall treatment plan to stay on track and aligned with their goals.

It’s a thoughtful approach, made possible by the precision and minimal recovery time of Cryoablation.
❄️📅🧬

https://www.cryoablation.com/

Address

Glendale, CA

Opening Hours

Wednesday 9am - 5pm
Thursday 9am - 5pm

Telephone

+18002035515

Website

http://www.cryoablation.com/

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