Dennis R. Holmes M.D., F.A.C.S.

Dennis R. Holmes M.D., F.A.C.S. Breast Cancer Surgery specializing in minimally invasive procedures to reduce the burden on breast cancer treatment. Dennis R. Holmes, M.D.

Find out more at www.drholmesmd.com or www.cryoablation.com is an internationally renowned breast cancer, surgeon, surgeon educator, and cancer researcher specializing in the management of breast cancer. Dr. Holmes is medical director of the Sam and Grace Carvajal Comprehensive Breast Center at Adventist Health Glendale in Los Angeles, CA. He is also Co-Founder and CEO of XpediteMD, Inc., a digital health technology company working to improve the efficiency, quality, and value of cancer care. Dr. Holmes completed his medical education at Tulane University School of Medicine, surgical residency in general surgery at the University of San Francisco, and a fellowship in breast surgery at the University of Southern California. Dr. Holmes is a board-certified Fellow of the American College of Surgeons and recently served as Program Chair of the 20th Annual National Meeting of the American Society of Breast Surgeons and is the 2023 Health Policy Scholar for the American College of Surgeons. He has also served as department head of several academic breast cancer programs and program director of two breast surgery fellowship programs. His has also played a pivotal role in several breast cancer treatment innovations, including intraoperative radiotherapy, oncoplastic surgery, and cryoablation.

You deserve options that don’t leave you feeling powerless.Cryoablation, a minimally invasive treatment, offers the free...
12/06/2025

You deserve options that don’t leave you feeling powerless.

Cryoablation, a minimally invasive treatment, offers the freedom to move forward on your terms, with less disruption, more control, and a team that truly listens. 💠🧊

https://www.cryoablation.com/

Many patients are surprised to learn that breast cancer treatment doesn’t have to mean losing sensation. Most patients r...
12/04/2025

Many patients are surprised to learn that breast cancer treatment doesn’t have to mean losing sensation.

Most patients retain full sensation because Cryoablation, a minimally invasive procedure, doesn’t require removal of tissue around the ni**le. Preserving both form and function is part of what makes this treatment different. It’s not just about eliminating cancer, it’s about protecting the physical experience of your body.🧊🩺🤍

If you’re ready to explore if this approach makes sense for your care plan, let’s connect!

https://www.cryoablation.com/

One of the most commonly asked questions we receive is, “Is Cryoablation safe for women in their 70s?”The answer is yes....
12/03/2025

One of the most commonly asked questions we receive is, “Is Cryoablation safe for women in their 70s?”

The answer is yes. Cryoablation, a minimally invasive procedure, is often an ideal choice for older women who want to avoid the risks that come with general anesthesia, hospital stays, and extended recovery times.

This treatment is typically done comfortably in an office setting under local anesthesia. It’s effective, gentle, and helps preserve quality of life, with many women returning to their routines quickly and without significant disruption.

Every case is unique. Reach out to see if Cryoablation may be a good fit for you or a loved one. 🎯❄️💙

Cryoablation, a minimally invasive procedure, doesn’t just preserve breast tissue, it helps preserve momentum. Many wome...
11/30/2025

Cryoablation, a minimally invasive procedure, doesn’t just preserve breast tissue, it helps preserve momentum. Many women are surprised to learn that they can return to physical activity, including strength training, much sooner than they would after surgery.

For patients who rely on fitness for stress relief, community, or confidence, this can be a major part of the healing process. Recovery should support your life, not interrupt it.💪❄️🏃‍♀️

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, is increasingly considered in cases where patients have a strong family hi...
11/28/2025

Cryoablation, a minimally invasive procedure, is increasingly considered in cases where patients have a strong family history or genetic predisposition to breast cancer.

For select individuals with BRCA or other high-risk mutations, treatment options are often framed as binary, surgery or surveillance.

Cryoablation offers a middle ground: local control without the physical and emotional toll of more aggressive interventions. It’s one more way we’re expanding the landscape of personalized, precision-based breast care.🧬🧊💡

https://www.cryoablation.com/

The impact of breast cancer often extends into deeply personal spaces, such as physical intimacy and a woman’s sense of ...
11/26/2025

The impact of breast cancer often extends into deeply personal spaces, such as physical intimacy and a woman’s sense of connection with her partner.

Cryoablation, a minimally invasive procedure, helps preserve the natural appearance and sensation of the breast, supporting confidence and comfort in close relationships. When treatment minimizes physical disruption, it can help maintain not only health, but also a sense of wholeness, identity, and ease in your own body.💗🧊🔗

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, may offer more than local control of breast cancer. As the tumor is frozen...
11/24/2025

Cryoablation, a minimally invasive procedure, may offer more than local control of breast cancer. As the tumor is frozen and destroyed, it releases tumor-specific antigens, proteins that your immune system can recognize and respond to. This process has the potential to stimulate a systemic immune response, almost like a personalized vaccine created from your own tumor.

This phenomenon, known as Cryoimmunotherapy, is still being explored in research settings, but it represents one of the most exciting frontiers in oncology. The idea that we can not only target a tumor directly but also activate the body’s natural defenses to seek out remaining cancer cells offers hope for a more comprehensive and less toxic treatment strategy.

I remain committed to advancing treatments that do more than remove disease, they empower the body to fight back.🛡️🧊💙

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, has received FDA clearance for certain breast tumors, an important milesto...
11/22/2025

Cryoablation, a minimally invasive procedure, has received FDA clearance for certain breast tumors, an important milestone that reinforces its role as a legitimate, evidence-based treatment option.

This advancement signals to patients, providers, and insurers alike that Cryoablation is not experimental, it’s safe, effective, and supported by rigorous clinical research.

I’ve spent years helping to move this treatment forward, not only through patient care but also through education, collaboration, and research. Every step has been driven by the belief that women deserve access to options that protect both their health and their sense of autonomy.❄️📜🧊

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, can often be performed in-office under local anesthesia, no hospital stay,...
11/20/2025

Cryoablation, a minimally invasive procedure, can often be performed in-office under local anesthesia, no hospital stay, no general anesthesia, and no lengthy recovery time.

For many women, that difference is profound. It’s not just about simplifying logistics, it’s about reducing risk, preserving autonomy, and easing the emotional toll that often comes with traditional breast cancer treatment.

I’ve seen how patients feel more at ease when their care is effective and accessible. It’s one of the reasons I continue to utilize this option for those who qualify.
🩺🧊

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, may be followed by a needle biopsy of the treatment site particularly in c...
11/18/2025

Cryoablation, a minimally invasive procedure, may be followed by a needle biopsy of the treatment site particularly in cases with a higher risk of recurrence.

This biopsy plays an important role in confirming that all cancer cells have been destroyed. It’s not always necessary, but when it is, it’s part of an informed, patient-centered approach to care.

I work closely with each individual to assess risk factors, timing, and next steps, so your follow-up plan is grounded in both science and personalized support.
❄️🔎

https://www.cryoablation.com/

If you live outside of Los Angeles, access to Cryoablation doesn’t have to feel out of reach. Cryoablation, a minimally ...
11/16/2025

If you live outside of Los Angeles, access to Cryoablation doesn’t have to feel out of reach. Cryoablation, a minimally invasive procedure, is typically performed in just one or two visits, making it a viable option for many women traveling from out of town.

I help patients streamline their care by coordinating imaging, testing, and follow-up, so the process is as efficient and low-disruption as possible. My goal is to reduce barriers, geographic or otherwise, so you can focus on healing without sacrificing quality of care or peace of mind.

If you’re considering Cryoablation and need support arranging travel and care logistics, I’m here to help make the process manageable and personalized.
✈️🧳❄️

https://www.cryoablation.com/

Cryoablation, a minimally invasive procedure, is sometimes misunderstood as experimental, but the science tells a differ...
11/15/2025

Cryoablation, a minimally invasive procedure, is sometimes misunderstood as experimental, but the science tells a different story. With over 100 published clinical trials and a growing body of evidence supporting its safety and effectiveness, Cryoablation is far from experimental, it’s evidence-based medicine in action.

This approach has been successfully used to treat tumors in the breast and beyond, offering women a thoughtful alternative to traditional surgery. I remain committed to advancing options that are backed by data, grounded in experience, and designed to protect both health and quality of life.🧊📚🔬

https://www.cryoablation.com/

Address

Glendale, CA

Opening Hours

Wednesday 9am - 5pm
Thursday 9am - 5pm

Telephone

+18002035515

Website

http://www.cryoablation.com/

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