11/22/2025
Depression comes in different forms, just as in the case of other illnesses such as heart disease. Within the major types of depression, there are also variations in the number of symptoms, how severe they are, and how long they last.
Major depression is manifested by a combination of symptoms (see symptom list) that interfere with the ability to work, study, sleep, eat, and enjoy once pleasurable activities. Such a disabling episode of depression may occur only once, but it more commonly occurs several times in a lifetime.
A less severe type of depression, dysthymia, involves long-term, chronic symptoms that do not disable, but keep one from functioning well or from feeling good. Many people with dysthymia also experience major depressive episodes at some time in their lives.
Symptoms of Depression
Persistent sad, anxious, or "empty" mood
Feelings of hopelessness, pessimism
Feelings of guilt, worthlessness, and helplessness
Loss of interest or pleasure in hobbies and activities that were once enjoyed, including s*x
Decreased energy, fatigue, being "slowed down"
Difficulty concentrating, remembering, or making decisions
Insomnia, early-morning awakening, or oversleeping
Appetite and/or weight loss, or overeating and weight gain
Thoughts of death or su***de; su***de attempts
Restlessness, irritability
Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain