KaKo Wellness and Healthcare Management LLC

02/10/2026

Think its just persistent allergies??

Do sulfites affect your health? Dr. A explains why some people react to sulfites while others don’t, the difference between sulfite and histamine reactions, ...

02/05/2026

✨ Exciting Updates at KaKo Wellness & Healthcare ✨

To better support our patients and keep care sustainable, we now offer tiered membership options—so you only pay for the level of care you need:

💚 Direct Primary Care (DPC) Membership
• $95/month
• One-time $100 enrollment fee
• Ideal for primary care, chronic condition management, and preventive care

🌸 Hormone Replacement Therapy (HRT) or Medical Weight Loss Program
• $150/month
• One-time $100 program enrollment fee
• Medications and labs not included, but offered at low cash-pay prices
• Reflects increased monitoring, labs, and prescribing responsibility

🧬 Functional Medicine “Deep Dive” Program
• $95/month DPC membership
• One-time $100 enrollment fee
• Additional $150/month while actively digging deep into root-cause care
• Specialty labs and supplements priced affordably at cash rates

This structure allows me to continue providing personalized, unrushed, root-cause care while keeping routine primary care accessible and affordable 💙

📩 Message us or call to see which option fits your health goals best!

01/30/2026

Send a message to learn more

01/23/2026

Priceless information

Many people believe their genes determine their health and that if something runs in the family, it’s inevitable.In this video, I explain why that belief is ...

01/21/2026

Trusted by patients with consistent 5-star ratings⭐️❤️⭐️❤️⭐️❤️⭐️❤️⭐️

01/20/2026

FUN FACTS..

Nutrition Deficiency Signs (With Important Clinical Cautions)

Many symptoms of “nutrient deficiency” are non-specific and overlap with hormone imbalance, thyroid dysfunction, anemia, sleep disruption, chronic stress, inflammation, medication effects, and perimenopause.

Because of this, supplements should not be taken blindly based on symptoms alone. In some patients, the wrong supplement, dose, or form can worsen symptoms.

Core Principles

Start food-first

Confirm deficiencies with labs when possible

Use low-and-slow dosing

Reassess symptoms and objective markers

Address pathway blockages before aggressive supplementation

Common Deficiency Patterns & Why You Shouldn’t “Just Take” Supplements

1. Fatigue, weakness, exercise intolerance

Possible contributors: iron/ferritin, B12, folate, magnesium, protein

Important cautions

Iron: Do not supplement without iron studies (ferritin, iron, TIBC, % saturation). Excess iron increases oxidative stress.

Folate: High-dose folate can worsen anxiety or insomnia in some individuals.

B12: Generally safe, but higher doses or stimulating forms may cause jitteriness in sensitive patients.

2. Anxiety, irritability, poor sleep

Possible contributors: magnesium, B6, zinc, glycine

Important cautions

B6: Helpful if deficient, but chronic high dosing can cause neuropathy.

Magnesium: Usually safe; GI side effects depend on form and dose.

Zinc: Long-term use can deplete copper if not monitored.

3. Hair loss, brittle nails, poor wound healing

Possible contributors: ferritin, zinc, protein, iodine, vitamin C

Important cautions

Biotin: Can interfere with lab testing (thyroid, cardiac markers).

Iodine: Excess can worsen autoimmune thyroid disease in some patients.

4. Palpitations, cramps, muscle twitching

Possible contributors: magnesium, potassium, calcium, iron

Important cautions

Palpitations may reflect thyroid disease, anemia, arrhythmia, dehydration, or medication effects—not just nutrients.

Potassium supplementation requires caution in kidney disease or with certain medications.

5. Histamine-type symptoms

(head pressure, flushing, dizziness, reflux, itching) Possible contributors: DAO activity, B6, vitamin C, copper balance, gut inflammation

Important cautions

Aggressive “detox” products, fasting, or high-intensity exercise can worsen symptoms.

Probiotics may help or worsen symptoms depending on strain selection.

Gene-Related Pathway Impairments: Treat the Environment First

Genetic variations do not cause disease by themselves. Symptoms arise when pathways are stressed, overloaded, or blocked. The priority is to remove stressors, then support pathways gently.

Step 1: Remove Common Pathway Blockers

This step often improves symptoms before supplements are added.

Poor sleep / circadian disruption

Chronic psychological stress

Alcohol

Ultra-processed foods and excess sugar

Chronic constipation (poor toxin and hormone clearance)

Mold or chemical exposure (if sensitive)

Overtraining / excessive HIIT

Ongoing inflammation or gut dysbiosis

Many “deficiency symptoms” improve simply by:

Adequate protein

Hydration

Sleep consistency

Regular bowel movements

Key Pathways That Affect Supplement Tolerance

A) Methylation Pathways

When stressed:

Fatigue

Brain fog

Anxiety

Poor stress tolerance

Support first with:

Adequate protein

Magnesium

Riboflavin (B2)

Gentle folate from food before supplements

Avoid early: high-dose methylated supplements in anxious or sensitive patients.

B) Catecholamine Breakdown (stress neurotransmitters)

When stressed:

Overstimulation

Anxiety

Insomnia

Irritability

Support first with:

Sleep regulation

Magnesium glycinate

Reduced caffeine/stimulants

Avoid early: aggressive methyl donors or stimulant-type supplements.

C) Histamine Clearance

When stressed:

Dizziness

Flushing

Head pressure

Reflux

Skin reactions

Support first with:

Lower histamine diet (fresh foods)

Gut healing

Regular bowel movements

Vitamin C, magnesium

DAO enzyme if food-triggered

Short-term H1/H2 blockade when appropriate

Avoid early: fasting, intense cardio, histamine-producing probiotics.

D) Detoxification / Glutathione Pathways

When stressed:

Chemical sensitivity

Headaches

Poor medication tolerance

Support first with:

Reduced exposures

Fiber + hydration

Glycine

Gentle sulfur foods

Avoid early: “hard detox” protocols or binders without bowel support.

Low-Risk “Foundation” Supports (Often Safe While Awaiting Labs)

Magnesium glycinate (evening)

Riboflavin (low dose)

Omega-3 DHA/EPA

Adequate protein intake (25–30 g per meal)

Fiber + hydration to ensure daily stooling

Targeted supplementation should follow lab confirmation.

Suggested Labs When Symptoms Persist

CBC, CMP

Ferritin, iron studies

B12 ± MMA/homocysteine

Folate

Vitamin D

Magnesium (RBC if available)

TSH, free T4, free T3 (± antibodies if indicated)

A1c, fasting insulin (if metabolic symptoms)

Bottom Line

Supplements are tools, not shortcuts.

Symptoms often reflect blocked or overloaded pathways, not just low nutrients.

Cleaning up sleep, stress, gut function, and inflammation comes first.

Repletion works best when it is targeted, gentle, and guided by labs.

KAKOHEALTHCARE.COM 352-534-6897

01/16/2026

FUN FACTS...Supplements: What NOT to Take Together (and What Can Be Dangerous)

More is not always better. Some supplements cancel each other out, and others can be unsafe when combined with medications.

🚫 Avoid taking these together: • Calcium + Iron (blocks absorption)
• Iron + Magnesium (compete for absorption)
• Zinc (high dose) + Copper imbalance
• Folic acid + Methylfolate (can block active folate)
• High-dose Vitamin A + High-dose Vitamin D
• Multiple minerals all at once (absorption drops)

⚠️ Be careful mixing supplements with medications: • Fish oil, turmeric, garlic, ginkgo, vitamin E + blood thinners → bleeding risk
• St. John’s Wort, 5-HTP, SAM-e + antidepressants → serotonin syndrome
• Licorice root + BP or heart meds → high BP, low potassium
• Calcium, iron, magnesium + thyroid meds → poor absorption (separate by 4 hours)
• Potassium or magnesium + kidney or heart meds → electrolyte risk

✅ Takeaway:
Supplements act like medications. Timing, dose, genetics, gut health, and prescriptions all matter. When in doubt—don’t stack everything together.

Always review supplements with your healthcare provider. Kako Wellness and Healthcare Management 352-534-6897

01/15/2026

FUN FACTS...KAKO WELLNESS 352-534-6897 Castor oil applied to the abdomen is commonly used in integrative and naturopathic care to support lymphatic movement, liver detoxification, and parasympathetic activation. While high-quality randomized trials are limited, the proposed mechanisms align with known physiology and are frequently observed clinically.
How Castor Oil May Support Lymphatic Drainage
1. Ricinoleic Acid Effects
Castor oil is rich in ricinoleic acid, which appears to:
Promote local vasodilation
Reduce inflammatory signaling
Increase capillary permeability, allowing improved fluid movement
This can indirectly support lymphatic flow, which relies on surrounding tissue motion and pressure gradients rather than a central pump.
2. Parasympathetic (Vagal) Activation
Abdominal castor oil packs are associated with:
Increased parasympathetic tone
Reduced sympathetic “fight-or-flight” activity
Because lymphatic flow improves during parasympathetic dominance (deep breathing, rest, digestion), this nervous-system shift is likely a key contributor.
3. Fascial and Interstitial Fluid Release
Warm castor oil:
Softens fascial restrictions
Improves interstitial fluid exchange
May help decongest stagnant lymph, especially in the mesenteric and portal regions
This is particularly relevant for individuals with chronic inflammation, constipation, hormonal congestion, or post-surgical adhesions.
4. Liver–Lymph Interface Support
The liver produces a large portion of lymph fluid daily. Castor oil packs placed over the right upper quadrant are thought to:
Support hepatic lymph flow
Improve bile movement
Reduce hepatic congestion, indirectly improving systemic lymphatic clearance

01/14/2026

Klako Wellness and Healthcare Management lKepy Safety Concerns with Vitamin A Supplementation

1. Toxicity Risk (Hypervitaminosis A)

Most important risk.

More likely with:

Preformed vitamin A (retinol, retinyl palmitate/acetate)

Chronic intake > 10,000 IU (3,000 mcg RAE) daily

Liver-based supplements or cod liver oil

Concurrent fortified foods

Symptoms

Headache

Dizziness

Nausea

Dry skin, hair loss

Bone pain

Elevated liver enzymes

Visual changes

2. Liver Toxicity

Vitamin A is stored in the liver.

Higher risk in:

Liver disease (NAFLD, hepatitis, cirrhosis)

Alcohol use

Older adults

Avoid supplementation unless deficiency is documented.

3. Bone Loss & Fracture Risk

Chronic excess vitamin A:

Antagonizes vitamin D

Increases osteoclast activity

Associated with higher hip fracture risk, especially in postmenopausal women

4. Pregnancy Risk (Teratogenic)

Preformed vitamin A is teratogenic.

Contraindicated in pregnancy beyond prenatal dosing:

Avoid retinol/retinyl esters

Beta-carotene is safer if supplementation is needed

5. Drug Interactions

Isotretinoin (Accutane) – additive toxicity (avoid completely)

Tetracyclines – ↑ intracranial hypertension risk

Warfarin – may increase bleeding risk

Cholestyramine/orlistat – ↓ absorption

6. Masking Other Deficiencies

High vitamin A can:

Mask vitamin D deficiency

Alter zinc utilization

Create imbalances rather than correct deficiencies

Safer Supplementation Principles

Prefer food sources (liver in moderation, eggs, dairy)

If supplementing:

Use low-dose

Avoid long-term daily use unless indicated

Monitor labs if using >2,500–5,000 IU regularly

Consider beta-carotene if conversion is adequate

Who Should Avoid Vitamin A Supplements

Pregnant or trying to conceive

Liver disease

Heavy alcohol use

On retinoids

Osteoporosis risk without monitoring

Bottom Line

> Vitamin A is essential—but more is not better. Preformed vitamin A has a narrow therapeutic window, and chronic excess can cause serious harm.

01/12/2026

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01/12/2026

Fun Facts About Vitamin C

(Especially important in peri- & post-menopause)

Vitamin C is a required co-factor.
Your body cannot make it — and midlife hormone shifts increase your need for it.

What Vitamin C Does (MOA)

Collagen integrity
• Required for collagen fiber stabilization
• Supports skin, tendons, ligaments, blood vessels
→ Estrogen decline accelerates collagen breakdown

Antioxidant & redox balance
• Neutralizes free radicals
• Regenerates glutathione
• Recycles vitamins C & E
→ Menopause increases oxidative stress

Neurotransmitter & adrenal support
• Required for norepinephrine synthesis
• Supports stress tolerance and focus
→ Low estrogen shifts stress load to adrenals

Immune modulation
• Supports innate immune cells
• Improves inflammatory resolution
→ Post-menopause immune balance often declines

Histamine & mast cell regulation
• Helps stabilize mast cells
• Reduces circulating histamine
→ Estrogen activates mast cells, worsening flushing, rosacea, itching

Iron handling
• Enhances iron absorption
→ Important nuance as iron needs change after me**es stop

Why Vitamin C Matters More After 40

• Skin thinning and sagging
• Slower tendon/ligament healing
• Easy bruising
• Hot flashes and flushing overlap with histamine
• Increased joint and vascular fragility

Vitamin C supports the structural framework estrogen used to protect.

Cautions (Important)

Form matters
• Some forms aggravate reflux or flushing
• Sensitive nervous systems may react poorly to acidic forms

Iron overload risk
• Enhances iron absorption
• Caution in high ferritin or hemochromatosis

Kidney considerations
• High oxidative load may increase oxalate burden

G6PD Deficiency (Critical Safety Note)

Vitamin C — especially IV vitamin C — can be unsafe in G6PD deficiency.

Why: • G6PD protects red blood cells from oxidative stress
• High-dose vitamin C can become pro-oxidant
• Risk of acute hemolysis

Key points • G6PD screening is required before IV vitamin C
• IV vitamin C is contraindicated in known G6PD deficiency

IV Vitamin C (Medical Use Only)

IV vitamin C is pharmacologic, not nutritional.

• Acts differently than oral vitamin C
• Produces controlled oxidative effects
• Used in select inflammatory, immune, and oncology settings

Requires: • Proper screening
• Renal function awareness
• Experienced medical oversigh

Key Takeaway

In menopause, vitamin C helps replace lost estrogen support for collagen, vessels, nerves, and histamine balance — but genetics, form, and delivery route matter. KaKo Wellness 352-534-6897

01/11/2026

FUN FACTS About B Vitamins

B vitamins are your body’s “spark plugs.”
They help convert food into energy, support the brain and nerves, and keep hormones, red blood cells, and detox pathways running smoothly.

The B-Vitamin Family (Kinds + What They Do)

B1 – Thiamine
• Helps turn carbohydrates into energy
• Supports nerve and heart function
• Low levels can cause fatigue, brain fog, and nerve symptoms

B2 – Riboflavin
• Activates other B vitamins
• Supports mitochondria (cell energy factories)
• Important for skin, eyes, and migraine prevention

B3 – Niacin
• Critical for energy production and DNA repair
• Supports cholesterol balance and circulation
• Can cause flushing in some people

B5 – Pantothenic Acid
• Needed to make adrenal hormones and cortisol
• Supports stress response and metabolism

B6 – Pyridoxine / P5P
• Helps make neurotransmitters (serotonin, dopamine, GABA)
• Supports histamine breakdown and hormone balance
• Too much of the wrong form can irritate nerves

B7 – Biotin
• Supports hair, skin, nails, and glucose metabolism
• Can interfere with lab tests (thyroid, troponin)

B9 – Folate (NOT folic acid)
• Critical for methylation, detox, hormones, and brain health
• Needed to make red blood cells and DNA
• Synthetic folic acid can block real folate in some people

B12 – Cobalamin
• Supports nerves, brain, and red blood cell formation
• Required for methylation and energy
• Absorption declines with age and gut issues

How B Vitamins Work (MOA – in simple terms)

• Act as co-enzymes → they “turn on” chemical reactions
• Drive energy production (ATP)
• Support neurotransmitter production
• Help the liver detox hormones and chemicals
• Regulate homocysteine (cardiovascular and brain health)

Without enough B vitamins, reactions slow down—even if calories are adequate.

Why Some People Feel Worse on B Vitamins

1. Wrong Form
• Folic acid instead of methylfolate
• Pyridoxine instead of P5P
• Cyanocobalamin instead of methyl- or hydroxy-B12

2. Genetics (“Dirty Genes”)
• MTHFR, COMT, MTR, MAO, DAO variants
• Can cause anxiety, irritability, insomnia, or headaches when over-stimulated

3. Overmethylation or Undermethylation
• Too much = anxiety, racing thoughts, irritability
• Too little = fatigue, depression, poor detox

4. Histamine Intolerance
• B6, B12, and folate can increase histamine temporarily
• DAO deficiency makes this worse

5. Gut Absorption Issues
• Low stomach acid
• SIBO, mold exposure, celiac, IBD
• Post-menopause and chronic stress reduce absorption

6. Dose Is Too High
• More is NOT better
• High doses can overwhelm sensitive nervous systems

Key Takeaway

B vitamins are powerful.
They are essential—but they must be: • The right form
• The right dose
• Matched to your genetics, gut, hormones, and histamine tolerance

This is why “one-size-fits-all” B-complex supplements often fail.

Welcome to Kako Wellness and Healthcare, where your health is our priority! We're all about providing personalized care with a friendly touch. Our skilled nurse practitioner is here to help you feel your best, whether it's through wellness tips, healthcare advice, or just a chat about your health jo...