10/19/2025
Science shows that even after birth, a child’s DNA can remain inside a mother’s body for years, sometimes a lifetime. These fetal cells travel through her blood, settle in her brain and organs, and become part of her. The phenomenon is known as fetal-maternal microchimerism.
Research led by Amy Boddy, associate professor at UC Santa Barbara, has found these cells in a wide range of maternal tissues. She describes it as “a small amount of genetically different cells or DNA in someone’s body.”
Some of these cells even take on new roles. For example, fetal cells that migrate to the mother’s heart can transform into cardiac cells, working alongside her own to help that organ function. It’s a biological connection that quite literally beats on.
Even after a miscarriage, fetal cells remain in the mother’s body. For women who experience pregnancy loss, “it’s not just in their head that they’re forever changed by that pregnancy,” Boddy says. “Those cells may exist and influence their biology.”
With so much we still don’t know about how these cells function, one thing is certain: motherhood leaves a mark that science is only beginning to understand.
Credit The Female Quotient
https://www.facebook.com/photo/?fbid=1429591659203840&set=a.472059978290351
Fetal microchimerism and maternal health: A review and evolutionary analysis of cooperation and conflict beyond the womb
Amy M. Boddy, Angelo Fortunato, Melissa Wilson Sayres, Athena Aktipis
First published: 28 August 2015 https://doi.org/10.1002/bies.201500059
Abstract
The presence of fetal cells has been associated with both positive and negative effects on maternal health. These paradoxical effects may be due to the fact that maternal and offspring fitness interests are aligned in certain domains and conflicting in others, which may have led to the evolution of fetal microchimeric phenotypes that can manipulate maternal tissues. We use cooperation and conflict theory to generate testable predictions about domains in which fetal microchimerism may enhance maternal health and those in which it may be detrimental. This framework suggests that fetal cells may function both to contribute to maternal somatic maintenance (e.g. wound healing) and to manipulate maternal physiology to enhance resource transmission to offspring (e.g. enhancing milk production). In this review, we use an evolutionary framework to make testable predictions about the role of fetal microchimerism in lactation, thyroid function, autoimmune disease, cancer and maternal emotional, and psychological health.
https://onlinelibrary.wiley.com/doi/full/10.1002/bies.201500059