Direct Functional Medicine

Direct Functional Medicine Direct Functional Medicine (located in Mebane, and Clayton, NC) also treats patient virtually across all of NC and VA.

Visit our website at DirectFunctionalMed.com to see the conditions we treat and to set up a free Meet and Greet.

04/19/2026

There is an important difference between simply being prescribed hormones for menopause and working with a hormone-focused specialist.

In many conventional primary care or gynecology settings, hormone therapy is often approached with a very narrow goal: relieve hot flashes and menopausal symptoms using the lowest effective dose of estrogen and progesterone for the shortest amount of time. While this can help with symptom relief, the framework is largely symptom-driven and time-limited.

Direct Functional Medicine approach looks at the bigger picture.

The question shifts from “What dose stops hot flashes?” to:

• What is the optimal hormone balance of estrogen, progesterone, DHEA and testosterone for the patient?
• How can we support long-term brain, bone, and cardiovascular health?
• How are these hormones impacting cellular energy, cholesterol metabolism, and insulin sensitivity?
• How is the patient’s body actually metabolizing and responding to hormones?

The goal is not just to reduce symptoms, but to optimize physiology and long-term health outcomes. That means considering hormones as part of a broader system that influences cognition, metabolism, cardiovascular risk, and overall vitality.

Menopause management doesn’t have to be limited to “lowest dose for shortest time.” It can be an opportunity to support women in maintaining strength, clarity, and metabolic health for decades to come.

04/19/2026

Being a patient at Direct Functional Medicine means having a provider who doesn’t rely on outdated protocols or rushed, one-size-fits-all care. It means working with someone who stays current with evolving research, questions conventional norms when appropriate, and is willing to dig deeper to find the most effective, up-to-date approaches for your health.

It’s a root cause model that focuses on the 8 pillars of health which include cellular function, toxins, biofilms, immunology (infections and autoimmunity), endocrine balance, psychosocial health, Digestive issues and structural health—not just symptoms.

You’re not just another chart. Your provider takes the time to research, collaborate, and personalize your care plan so you’re getting thoughtful, evidence-informed guidance—not guesswork.

04/09/2026

Our office is closed today and will reopen tomorrow.

04/08/2026

We have an open position for a massage therapist trained in deep tissue, psoas and plantar fasciitis massage. This is a W2 position with CE benefits. Please send resumes to DirectPrimaryCareMebane@gmail.com

04/03/2026

I am happy to see that there are oncologists looking into hormones after breast cancer. There are several published studies showing estradiol decreases risk of breast cancer. Now we need studies for our cancer survivors. We should not leave these women at increased risk of osteoporosis, cardiovascular disease, dementia and poor quality of life if it is safe to give hormones after breast cancer treatment.

https://ascopubs.org/doi/10.1200/JCO-25-03121

02/01/2026

Due to road conditions our office will be closed until 1:00 PM on Tuesday February 3rd with the exception of already scheduled virtual visits.

01/25/2026

Due to road conditions our office will be closed tomorrow.

01/13/2026

Proton pump inhibitors (PPIs) have been linked in recent 2025 and 2026 research to an increased risk of high blood pressure (hypertension) through the suppression of nitric oxide (NO) bioavailability. Research indicates that long-term PPI use—typically one year or longer—is associated with a 17% to 28% higher risk of incident hypertension.

https://www.ahajournals.org/doi/10.1161/JAHA.124.040009 #:~:text=Long%E2%80%90term%20proton%20pump%20inhibitor,with%20higher%20risk%20of%20hypertension.&text=New%20users%20and%20continued%20users,users%20had%20no%20significant%20association.

01/11/2026

A recent large-scale study from 2025, included those using electronic health records and mouse models, show chronic Lyme disease (LD) significantly increases the risk for several gynecological issues like heavy periods (menorrhagia), uterine fibroids, endometriosis, and miscarriage, suggesting Borrelia burgdorferi can persist in the female reproductive tract, causing inflammation and pathology. Research indicates potential links to ovarian cysts, dysmenorrhea (painful periods), and even severe complications in pregnancy if untreated.

12/14/2025

As a mold literate nurse practitioner and functional medicine practitioner I have learned that mold toxicity is more common than people think.

Conventional medicine professionals do not know or understand mold toxicity and can’t help.

Mold is usually not visible in your home. Even new builds have mold and since mold is expensive to remediate some people will sell their homes instead of remediating the mold. I have had patients unknowingly move from one mold toxic home to another.

In NC mold is not on the inspection report when buying a home.

Many mold/water damage professionals are not properly trained about how to test for mycotoxins or about how sick mold can make people. An air test alone can’t rule out mycotoxins.

Once your home is remediated you need to have your personal items cleaned. If they can’t be cleaned you may need to throw them away. In order to properly detox you can’t be actively exposed to mold in your home or work.

There are several mycotoxin tests people can take for mold toxicity all have their pros and cons.

It is not uncommon for there to be people in the same home that are not sick. This is due to differences in methylation SNPs, detox pathways, nutrition, gut health and HLA genes.

Not everyone with mycotoxin illness has CIRS.

There are different protocols and there is not one protocol that works to detox everyone. Mold detox should be personalized to the patient and types of mycotoxins present in their body.

Some people take longer to heal than others. It can takes years to heal from mold toxicity, especially if you have been under chronic stress for years or have had childhood trauma.

In order to heal a practitioner should look at nutrient levels, mitochondrial function, think about possible biofilms and co-infections, check and support gut health, support any endocrine imbalances such as adrenal gland, s*x hormone and thyroid issues. Support brain health and detox.

There is a process to healing the body. Detox is the last step in the process.

And yes, mold is everywhere. It is in the air outside but if your body is supported and you are not living in a toxic moldy environment you can heal.

11/12/2025

Our phones and Internet are down today. We will return your calls and messages as soon as we can. I apologize for the inconvenience.

10/19/2025

PCOS is characterized by metabolic dysfunction. ovulatory disturbance, and hyperandrogenism. Main stream providers treat this condition with Metformin and birth control pills. Many of these patients have a genetic issue called MTHFR C677T. This enzyme is critical for how your body uses folate which is needed in the methylation cycle for healing, detox and DNA/RNA syntheses. Metformin and birth control decrease folate levels and methylation in the body. If a patient with PCOS already has a decrease in folate due to this genetic issue and they are given metformin and birth control this decreases their bodies ability to use folate even more leading to more disease and illness. These patients need to work with a functional provider to work on the root of illness not prescribed medications that make them worse.

Address

302 West Graham Street
Mebane, NC
27302

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 12pm

Telephone

+19195680499

Website

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