Direct Functional Medicine

Direct Functional Medicine Direct Functional Medicine (located in Mebane, and Clayton, NC) also treats patient virtually across all of NC and VA.

Visit our website at DirectFunctionalMed.com to see the conditions we treat and to set up a free Meet and Greet.

12/14/2025

As a mold literate nurse practitioner and functional medicine practitioner I have learned that mold toxicity is more common than people think.

Conventional medicine professionals do not know or understand mold toxicity and can’t help.

Mold is usually not visible in your home. Even new builds have mold and since mold is expensive to remediate some people will sell their homes instead of remediating the mold. I have had patients unknowingly move from one mold toxic home to another.

In NC mold is not on the inspection report when buying a home.

Many mold/water damage professionals are not properly trained about how to test for mycotoxins or about how sick mold can make people. An air test alone can’t rule out mycotoxins.

Once your home is remediated you need to have your personal items cleaned. If they can’t be cleaned you may need to throw them away. In order to properly detox you can’t be actively exposed to mold in your home or work.

There are several mycotoxin tests people can take for mold toxicity all have their pros and cons.

It is not uncommon for there to be people in the same home that are not sick. This is due to differences in methylation SNPs, detox pathways, nutrition, gut health and HLA genes.

Not everyone with mycotoxin illness has CIRS.

There are different protocols and there is not one protocol that works to detox everyone. Mold detox should be personalized to the patient and types of mycotoxins present in their body.

Some people take longer to heal than others. It can takes years to heal from mold toxicity, especially if you have been under chronic stress for years or have had childhood trauma.

In order to heal a practitioner should look at nutrient levels, mitochondrial function, think about possible biofilms and co-infections, check and support gut health, support any endocrine imbalances such as adrenal gland, s*x hormone and thyroid issues. Support brain health and detox.

There is a process to healing the body. Detox is the last step in the process.

And yes, mold is everywhere. It is in the air outside but if your body is supported and you are not living in a toxic moldy environment you can heal.

11/12/2025

Our phones and Internet are down today. We will return your calls and messages as soon as we can. I apologize for the inconvenience.

10/19/2025

PCOS is characterized by metabolic dysfunction. ovulatory disturbance, and hyperandrogenism. Main stream providers treat this condition with Metformin and birth control pills. Many of these patients have a genetic issue called MTHFR C677T. This enzyme is critical for how your body uses folate which is needed in the methylation cycle for healing, detox and DNA/RNA syntheses. Metformin and birth control decrease folate levels and methylation in the body. If a patient with PCOS already has a decrease in folate due to this genetic issue and they are given metformin and birth control this decreases their bodies ability to use folate even more leading to more disease and illness. These patients need to work with a functional provider to work on the root of illness not prescribed medications that make them worse.

Quick Overview of Thyroid Hormones:• T4 (Thyroxine): Produced by the thyroid gland; it's a prohormone. It has very littl...
09/21/2025

Quick Overview of Thyroid Hormones:
• T4 (Thyroxine): Produced by the thyroid gland; it's a prohormone. It has very little direct activity.

• T3 (Triiodothyronine): The active form of thyroid hormone. It’s what your cells actually use to regulate metabolism, energy, mood, body temperature, and more.

• Free T3 (FT3) and Free T4 (FT4): The “unbound” forms, which are bioavailable (usable by the body).

• TSH (Thyroid Stimulating Hormone): Made by the pituitary gland to regulate thyroid output.
________________________________________
🔁 Why T3 Matters (and Why T4 Alone Can Be Misleading):

1. T4 Must Convert to T3 to Work
• T4 is converted to T3 in the liver, gut, and other tissues.
• Some people have impaired conversion, due to:
• Chronic illness
• Inflammation
• Stress or high cortisol
• Nutrient deficiencies (like selenium, zinc, iron)
• Certain medications
👉 So, even if T4 and TSH are "normal", if conversion is poor, Free T3 can be low, and the person can still have hypothyroid symptoms.
________________________________________
2. Low T3 = Hypothyroid Symptoms
Patients with low T3 may experience:
• Fatigue
• Brain fog
• Depression/anxiety
• Cold intolerance
• Weight gain
• Constipation
• Hair thinning
Even if TSH and T4 are in range, if Free T3 is low, the person can feel very unwell.

Direct Functional Medicine Offices in Mebane and Clayton Schedule a Meet & Greet Schedule An Appointment No matter where you live in North Carolina, you have access to quality Functional Medicine Care from the comfort of your home! Don’t pay thousands of dollars upfront for Functional Medicine! No...

09/21/2025

Conventional providers do not think women need testosterone but there are many benefits of testosterone for women which is why we are supposed to produce it.

Mood & Mental Health

Mood Regulation: Adequate testosterone levels are associated with better mood stability and lower rates of depression or anxiety.

Confidence and Drive: It can improve motivation, assertiveness, and overall sense of well-being.

Sexual Health

Libido: Testosterone supports healthy s*xual desire and arousal.

Vaginal Health: Supports vaginal tissue health, helping with lubrication and reducing discomfort during s*x.

Energy & Vitality

Fatigue Reduction: Low testosterone can cause fatigue; restoring levels may boost energy.

Improved Resilience: May help with mental and physical endurance.

Muscle Mass & Strength

Lean Muscle Maintenance: Supports muscle development and helps prevent muscle loss, especially post-menopause.

Improved Physical Performance: May increase strength, endurance, and recovery from exercise.

Bone Health

Bone Density: Works in synergy with estrogen to maintain bone strength and reduce risk of osteoporosis.

Cognitive Function

Memory and Focus: Some evidence suggests testosterone may aid in memory, focus, and cognitive sharpness.

09/20/2025

We are now open in downtown Clayton at 423 East Second Street.

07/06/2025

Due to flooding in our area the office will be closed tomorrow.

05/28/2025

When trying to lose weight the goal is to do it in a healthy way. I have heard of places that tell patients to decrease calories to 700-800 calories per day. This is not sustainable. It also slows metabolism and thyroid function. This will lead to more weight gain once you come off of the diet/weight loss medicine.

If you are taking a GLP medication and decreasing calories to these levels you can lose muscle mass. A loss of muscle mass also slows down metabolism.

The goal should be eating healthy whole foods and exercising while focusing on reasons you may not be losing weight such as imbalances in your body.

If you choose to add a GLP medication make sure you are still getting enough calories and protein.

Yale published about post vaccine syndrome. The publication discuss symptoms such as brain fog and fatigue but also stat...
04/04/2025

Yale published about post vaccine syndrome. The publication discuss symptoms such as brain fog and fatigue but also states "From participants’ blood samples, the researchers looked for immune features that were different between the two groups. They found several differences in immune cell populations; those with PVS had lower levels of effector CD4+ T cells and higher levels of TNF-alpha+ CD8 T cells — both are types of white blood cells — among other differences."

https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directions

Lower levels of effector CD4+ T cells and higher levels of TNF-alpha+ CD8 T cells (both types of white blood cells) can indeed increase the risk of cancer, as they can disrupt the cancer-immunity cycle and impair the body's ability to effectively fight tumors.

https://www.sciencedirect.com/science/article/pii/S1074761323004107 #:~:text=CD4+%20T%20cells%20can%20have,the%20CD4+%20T%20cell%20compartment.

If you are experiencing these symptoms or concerns, please reach out for a free Meet and Greet through our website at directfunctionalmed.com

A small number of people report chronic symptoms after receiving COVID-19 shots. A new study provides clues for further research.

Long COVID is debilitating and difficult to treat because it is a complex illness. Studies show it can cause thyroid dys...
04/04/2025

Long COVID is debilitating and difficult to treat because it is a complex illness.

Studies show it can cause thyroid dysfunction, vitamin deficiencies, gut health imbalances, mitochondrial deficiencies, adrenal gland problems, elevated estrogen and can be more prevalent in people with an MTHFR gene mutation.

All of these plus toxins need to be evaluated and treated in patients with Long COVID.

If you have been told you have Long COVID and are interested in getting advanced testing and treatment please schedule a Free Meet and Greet through our website at

Direct Functional Medicine Offices in Greensboro, High Point and Mebane Schedule a Meet & Greet Schedule An Appointment No matter where you live in North Carolina, you have access to quality Functional Medicine Care from the comfort of your home! Don’t pay thousands of dollars upfront for Function...

03/08/2025

Leptin is a hormone made by fat cells to keep food intake and weight balanced. It is released by the brain to control the sensation of feeling full. Leptin resistance can alter metabolism and makes people feel hungry and eat more. There are several causes for leptin resistance, including chronic inflammation, stress, leaky gut, gut bacteria overgrowth or gut microbiome imbalance, nutrient deficiencies, and toxins. If you think you may be struggling with Leptin resistance please schedule a free Meet and Greet at www.directfunctionalmed.com

03/06/2025

A sign of vitamin D deficiency is binge eating. Impaired satiety and the tendency to overeat are often seen in people who have low vitamin D levels.

Low vitamin D also leads to weight gain because your metabolism slows down.

Address

302 West Graham Street
Mebane, NC
27302

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 12pm

Telephone

+19195680499

Alerts

Be the first to know and let us send you an email when Direct Functional Medicine posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Direct Functional Medicine:

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram