02/09/2026
Cardiovascular disease (CVD) is becoming more common in young women across the United States. Hypertensive disorders of pregnancy (HDP) is a group of conditions that include high blood pressure during pregnancy, such as preeclampsia and gestational hypertension. It is increasingly recognized as early warning signs of future heart and blood vessel problems. What has been less clear is whether HDP directly contributes to later heart disease or simply reflects underlying health risks that were already present before pregnancy.
To better understand this relationship, researchers studied a large, diverse group of women using real-world health data and confirmed their findings across multiple healthcare systems. This study used data from the All of Us Research Program, which includes more than 50 health systems across the U.S., and followed 17,357 women who were pregnant between 2007 and 2022.
Researchers examined whether women who experienced HDP were more likely to develop premature cardiovascular disease, meaning heart disease or stroke occurring at a relatively young age.
This study did not separate different types of HDP, which may carry different long-term heart risks. Future research with more detailed pregnancy information could help clarify whether factors such as timing, severity, or type of HDP affect heart disease risk differently and allow for more personalized prevention strategies.
TAKE HOME MESSAGE: Hypertensive disorders of pregnancy increase the risk of early heart disease, even in women who had no heart or metabolic health problems before pregnancy. Supporting heart health before, during, and after pregnancy and including pregnancy complications in cardiovascular risk assessments may help reduce the growing rates of early-onset heart disease among women.
Read more about the study here: https://www.preeclampsia.org/the-news/research/do-hypertensive-disorders-of-pregnancy-increase-the-risk-of-early-heart-disease-in-young-women