Sana Vida Wellness Center

12/05/2025

Learn about autophagy benefits in longevity science. Understanding that cellular repair through autophagy can extend lifespan and improve healthy aging naturally.

12/05/2025

Heatstroke and heat exhaustion are serious summer diseases — learn to spot key heatstroke symptoms and how to respond to protect yourself and loved ones.

12/05/2025

Learn more about silent kidney disease signs, chronic kidney symptoms, and kidney failure early signs that are often ignored.

12/05/2025

Discover the longevity diet secrets: blue zones foods like beans, greens, and nuts, plus healthy aging tips from world's longest-living people for vibrant, extended lifespan.

12/05/2025

Discover why morning bloating happens, common bloated stomach causes, and how digestive problems may be involved. Expert tips to ease discomfort and improve gut health.

12/05/2025

Stomach pain after eating often stems from indigestion causes or food intolerance. Learn what doctors check first, key triggers, diagnostic steps, and effective relief.

12/05/2025

Morning headaches often stem from sleep-related headaches, apnea, bruxism, or poor sleep habits. Learn what causes them and how simple strategies can prevent daily pain.

12/05/2025

Ever wonder why caffeine hits you harder, stress lingers longer, or pain feels more intense than it “should”? COMT rs4680 might be part of the story.

COMT (catechol-O-methyltransferase) is the enzyme that clears dopamine, epinephrine, and norepinephrine—the brain’s focus and stress chemicals. “rs4680” is a common location in the COMT gene where a tiny DNA change (Val→Met at position 158) alters how fast this enzyme works.

What a COMT rs4680 mutation can mean:

* **Val/Val (faster COMT):** You clear stress chemicals quickly. Often solid under pressure, but you may burn through focus faster or chase stimulation.
* **Met/Met (slower COMT):** You keep more dopamine around. Great for deep focus when calm, but you can be more sensitive to stress, caffeine, and pain; estrogen by-products may clear more slowly.
* **Val/Met:** In-between, with traits from both.

Important: “Mutation” here isn’t “bad” or a diagnosis—it’s a common genetic variant that shapes how your body processes stress signals (and, for many, estrogen). Knowing your type helps you work *with* your biology.

Practical takeaways:
• Prioritize sleep, strength training, and daily stress resets (breath work, walks).
• Be intentional with caffeine; slower COMT types often do better with less.
• Support neurotransmitter and hormone metabolism with protein-rich meals, leafy/cruciferous veggies, fiber, and adequate B-vitamins and magnesium.
• Supplements are not one-size-fits-all—discuss them with your clinician.

I see both patterns in clinic every week. When patients understand COMT rs4680, choices about focus, recovery, and hormone care get clearer. Curious where you land? Ask about a simple genetic or lab-informed review and we’ll tailor a plan.

12/05/2025

12/04/2025

Recognizing early symptoms and health warning signs helps prevent severe illness. Learn the 12 ignored symptoms and how awareness improves long-term health outcomes.

12/04/2025

A clear guide to sudden heart racing, heart palpitations causes, and rapid heartbeat risks, plus when symptoms signal a medical emergency and need professional care.