Addario Lung Cancer Medical Institute - ALCMI

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Addario Lung Cancer Medical Institute - ALCMI

We fund and support investigator-led lung cancer clinical trials.

03/27/2026

Fascinating! Researchers have identified that lung cells age at different rates, with implications for lung cancer risk and targeted therapies.

There are many serious health conditions and diseases that are associated with aging, like pneumonia, as well as lung cancer and COPD ... | Cell And Molecular Biology

03/26/2026

New research into treatment resistance! Researchers at Johns Hopkins Medicine have identified a promising new therapeutic target that could overcome one of the most stubborn challenges in small cell lung cancer treatment.

Abstract. Small cell lung cancer (SCLC) is characterized by early metastasis, intrinsic chemoradiation resistance and tumor recurrence. Besides the lack of potentially targetable oncogenic drivers, therapeutic advancements are also hindered by the scarcity of surgically resected tissue specimens ide...

03/25/2026

Researchers at VCU Massey Comprehensive Cancer Center have uncovered a critical vulnerability in p53-mutant lung tumors, and it could reshape how we treat a majority of patients.

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA replication in cancer cells. The new findings published in Cell Death & Differentiation support a...

03/24/2026

We'll be keeping tabs on this one. bioAffinity Technologies has launched a landmark 2,000-patient longitudinal study that could redefine how we approach early lung cancer detection.

SAN ANTONIO, March 10, 2026--bioAffinity Technologies launches 2,000-patient longitudinal study for its CyPath Lung noninvasive diagnostic for lung cancer.

03/23/2026

Wow! Researchers at Dartmouth College and Baylor University have identified a DNA methylation signature that distinguishes the two major subtypes of non-small cell lung cancer and predicts early survival in smokers with lung squamous cell carcinoma.

AbstractIntroduction. Lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) are the two major histologic subtypes of non-small cell lung cance

03/22/2026

Medicaid expansion under the Affordable Care Act is saving lives, and a landmark study of more than 514,000 NSCLC patients now quantifies exactly how much.

A nationwide analysis of adults newly diagnosed with non-small cell lung cancer found that Medicaid expansion was associated with earlier-stage diagnosis, more timely initiation of guideline-concordant treatment and improved five-year survival.

03/21/2026

Researchers at Novant Health have found that delaying immunotherapy initiation in extensive-stage small cell lung cancer does not compromise survival outcomes, offering a clinically meaningful insight for patients who require emergent hospitalization at diagnosis.

BACKGROUND: Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive form of lung cancer associated with poor prognosis, and treatment goals are focused on prolonging survival and symptom palliation. Recent phase 3 trials have led to the approval of immunotherapy in the frontline setting fo...

03/20/2026

Researchers at the University of Gothenburg have uncovered a key molecular driver of lung cancer metastasis in older patients.

Lung tumors often grow more slowly but are more likely to spread to other organs, a pattern linked to increased activity of the protein ATF4.

03/19/2026

Whoa! This is big. Researchers at UVA Health have identified a direct link between severe respiratory viral infections and increased lung cancer risk.

A severe case of COVID-19 or influenza could increase the risk of lung cancer later on, according to new research. Scientists discovered that serious viral infections can alter immune cells in the lungs, leaving behind chronic inflammation that may help tumors develop months or years later. The incr...

03/18/2026

Moffitt Cancer Center researchers have identified a more powerful predictor of immunotherapy response in non-small cell lung cancer than PD-L1 status alone.

Study shows tumor microenvironment ecology predicts response better than PD-L1 status alone

03/04/2026

Median Technologies' Eyonis LCS has received FDA 510(k) clearance as the first AI-based device for both detecting and diagnosing lung cancer in low-dose CT scans.

This device detects and characterizes lesions on low-dose CT scans, helping patients with cancer get faster, tailored care and avoid unnecessary procedures.

03/03/2026

Congratulations to Misty Shields and colleagues at the Indiana University School of Medicine and Moffitt Cancer Center!

Abstract. Small cell lung cancer (SCLC) is a recalcitrant thoracic malignancy known for acquired chemoresistance, early metastatic spread, and poor overall survival. Lurbinectedin, a DNA minor groove alkylating agent, provides durable efficacy in a minority. Predictive biomarkers for lurbinectedin a...

Address

1100 Industrial Road, Suite 1
San Carlos, CA
94070

Telephone

+16505982857

Website

https://alcmi.org/

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