Emily Sadri, NP

Emily Sadri, NP Emily Sadri is a Women's Health + Functional Medicine expert, offering health and hormone advice.

I’d rather pass on other things. Maybe it’s because I was unhealthy and miserable for so many years. Maybe it’s because ...
04/22/2026

I’d rather pass on other things.

Maybe it’s because I was unhealthy and miserable for so many years. Maybe it’s because I’ve watched my family members, in succession, lose decades to insulin resistance, fatty liver, and neuro-degeneration.

My health, and my family’s health, are the most important things.

It adds to my productivity.
My self-actualization.
My energy.
My parenting reserves.

I’m in it for the long game.

If I didn’t have the ability to invest this much?

Is double down:
Hormones
A few key supplements
Sun
Community
Sleep
Movement

You don’t have to do what I do.

Spending every day talking to women in menopause who’ve lost so much time feeling unwell — I’m unavailable for that outcome.

Did I offend you?

Today is day 9 of my 30 day HRT in Peri Series.

Commercial HRT can be $50 or less per month. It might relieve symptoms. I don’t believe it’s optimal for physiology. Injections might be the exception.

What Q’s do you have?

Follow so you don’t miss a day:



’d rather pass on other things. Maybe it’s because I was unhealthy and miserable for so many years. Maybe it’s because I...
04/22/2026

’d rather pass on other things.

Maybe it’s because I was unhealthy and miserable for so many years. Maybe it’s because I’ve watched my family members, in succession, lose decades to insulin resistance, fatty liver, and neuro-degeneration.

My health, and my family’s health, are the most important things.

It adds to my productivity.
My self-actualization.
My energy.
My parenting reserves.

I’m in it for the long game.

If I didn’t have the ability to invest this much?

Is double down:
Hormones
A few key supplements
Sun
Community
Sleep
Movement

You don’t have to do what I do.

Spending every day talking to women in menopause who’ve lost so much time feeling unwell — I’m unavailable for that outcome.

Did I offend you?

Today is day 9 of my 30 day HRT in Peri Series.

Commercial HRT can be $50 or less per month. It might relieve symptoms. I don’t believe it’s optimal for physiology. Injections might be the exception.

What Q’s do you have?

Follow so you don’t miss a day:



04/21/2026

This is day 8 of my 30 day series: Perimenopause and HRT.

You may have heard (especially here in IG land) that transdermal (cream) progesterone is terrible, and you should “run from any provider using it.”

Respectfully, that simply because the studies that looked at it for endometrial protection (how well it opposed estrogen in the uterus), only looked at doses of 40mg.

We would never surmise that 40mg of oral progesterone was sufficient. We always give it in 100-200mg (I dose it even higher, in short bursts, to mimic physiology).

Here is how I use progesterone cream:

+ Always compounded. Over the counter formulas are lower dose, and not sufficient

+ Always cyclically if it’s the only progesterone, and with a period to accompany it. Adequate progesterone rise and then fall will produce a period

+ Often I use it in peri for women who are still ovulating, tracking ovulation, and want to boost their self-produced levels

+ All women cycling hormones should get an annual pelvic ultrasound

Sometimes physiology makes more sense than pharmacology.

Have you heard that progesterone cream is bad?

Have you tried and liked it?

This is day 8 of my 30 day series on HRT in perimenopause ➡️

Follow:

So you don’t miss a post.

Respectfully, if your HRT provider isn’t checking your full thyroid panel, SHBG (binding proteins), nutrient levels and ...
04/20/2026

Respectfully, if your HRT provider isn’t checking your full thyroid panel, SHBG (binding proteins), nutrient levels and inflammatory markers — why are you still working with them?

We get one life. And one midlife transition. It has to be done right.

Every time I visit my Dad at his assisted living center (he has Parkinson’s) I look around at all the women and think about what was missed and ignored in their forties.

Thyroid hormone impacts liver metabolism, cholesterol levels and bone health (to name a few).

You want to get this one right.

Tell me your thyroid stories 👇

This is day 7 in the Perimenopause and HRT Series.

Share this with a fellow thyroid friend.

And follow 👉
so you don’t miss the next one.

At a certain point, if you want to feel better than ever in midlife you just accept that 90% of providers won’t be able ...
04/19/2026

At a certain point, if you want to feel better than ever in midlife you just accept that 90% of providers won’t be able to help you.

And that’s terrible, but true.

(See the day 5 post to understand more context)

Birth control is not hormone therapy. It may suppress bleeding but it doesn’t confer health benefits (bio-identical hormones do).

Trazadone is terrible for your brain. Your sleep architecture is broken because your brain is deprived of estrogen. Estrogen regulates circadian rhythm.

Anti-depressant Rx’s sky rocket after 40, in women. We’re not just all falling apart. We’re under resourced.

During your reproductive years you make progesterone 12-14 days per month. Not daily. And your sleep is fine.

Compounded medications are made with FDA approved ingredients. And the pharmacies are heavily regulated. Would you stop buying meat at the farmers market because it doesn’t contain a nutrition label?

Bio-identical hormone therapy does not cause breast cancer. Plain and simple.

If the plan you’re offered doesn’t feel right — find someone new.

Become your own best provider, and build your team.

Today is day 6 in my Perimenopause and HRT series.

I believe in replacing hormones earlier in perimenopause, to achieve optimal physiology.

Follow:
so you don’t miss a day in the series ❤️

I started HRT last week on a 32 year old. She had regular, 28 day cycles. Gut issues that weren’t getting better despite...
04/18/2026

I started HRT last week on a 32 year old.

She had regular, 28 day cycles.

Gut issues that weren’t getting better despite every. single. functional. intervention.

And mood issues that made her not recognize herself.

We had three months of Mira data to work with - and her follicular (first 14 days) phase of her cycle was characterized by “low amplitude estrogen.” In other words, it wasn’t doing what it was supposed to.

Two day on estrogen therapy and she was a new human.

It’s time we start treating all hormones equally, and seeing women’s total health through the lens of their ovarian health.

This is day 5 of 30 of The Perimenopause and HRT Series.

Follow along and share this with a friend so you don’t miss a day ❤️



I would wager that less than 1% of nursing mothers are offered bio-identical hormone support. While at least 90% are off...
04/16/2026

I would wager that less than 1% of nursing mothers are offered bio-identical hormone support.

While at least 90% are offered birth control.

Preventing the next pregnancy is not the only way to care for women.

In fact, it’s abysmal.

Postpartum is a slice of perimenopause. Over 35? It’s actual perimenopause.

If I could go back in time I would start hormones at age 40, when I was a year postpartum and really struggling.

I’d love to know - was this your experience, too?

This is day 4 of my 30 day HRT in Perimenopause Series.

Share this with someone who’s postpartum and could use more support.

And follow:

so you don’t miss the next installments.

The patch is fine if it’s used what it was intended for. In perimenopause when the primary concerns are energy, metaboli...
04/15/2026

The patch is fine if it’s used what it was intended for.

In perimenopause when the primary concerns are energy, metabolic changes and mood? It’s not my favorite.

Even if I’m using only 1/2mg twice per day, I’d rather do that with transdermal cream. I think the intermittent dosing allows the cycle to stay intact in the background. Less suppression, more endogenous rhythm.

It’s also more customizable.

If we want to support ovulation, I increase that 1/2mg on days 10, 11 and 12 of the cycle. It supports ovulation and primes progesterone receptors.

We’ve been having a symptom management conversation for too long.

One that doesn’t reflect female physiology, or respect it.

With an optimization lens, we need to look deeper.

Did you try a patch and feel good at first, and then worse? Or, did you love it? I want to know ❤️

Share this with a friend who’s in peri and trying to get the estrogen right.

This is day 3 in a 30 day series on HRT in perimenopause.

Follow so you don’t miss a post.

04/14/2026

The audio is messed up - just ignore the moving lips 🫠

Most importantly, the publishing space is super crowded right now in perimenopause and menopause.

This book is different: The Menopause Gut by

Buy 10 copies and I’ll gift you a free business coaching session - for anyone with a health business (or dreaming of starting one). Send me the purchase confirmation.

Only ten spots. Goes away in two weeks.

🎉📕❤️

I wish I could go along with the masses and tell you:Progesterone declines first. Estrogen is high initially, then wild,...
04/14/2026

I wish I could go along with the masses and tell you:
Progesterone declines first.
Estrogen is high initially, then wild, then low.

But that’s just not what I see.

The problem is, we’re applying linear thinking to a distinctly cyclical process.

Our hormones are not a straight line.

Estrogen is the primary female governing hormone. And it’s usually being introduced too late, and in too small a dose.

I use the Mira Monitor in many of my peri patients and here’s the pattern I’m seeing:

Failure of estrogen to peak in the first half of the cycle (between day 12-14).

This is the issue. Everything begins here.

I’ll dive more into this in my 30 days series: HRT in perimenopause. Today is day 2.

Follow along and share with a friend who’s surviving on scraps in peri:



I’m forty-four now, and I didn’t start HRT until shortly before my 42nd birthday. I went on to have another baby, and to...
04/13/2026

I’m forty-four now, and I didn’t start HRT until shortly before my 42nd birthday.

I went on to have another baby, and to have gestational diabetes for a second time, at age 38.

I turned 39 on maternity leave and left my hospital based job.

I was tired of feeling sick and overworked.

I was tired of a system that couldn’t explain to me why my metabolic health was falling apart, before my fortieth birthday.

This is the first post in my Perimenopause and HRT series.

I hope it helps at least one person in the way that I needed help at 36, 37, 38, 39, 30 and 41.

I was a highly educated and compassionate provider, and I didn’t fully get it.

Send this to a bestie who might be in peri, and I hope you’ll follow along.



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Shaker Heights, OH
44118, 44120, 44122

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