Dr. Paymon Sadrolsadot ND

02/29/2024

12/06/2023

National Integrated Health Associates (NIHA)
Leaders in integrative & functional medicine and holistic dentistry since 1995. Holistic health care under one roof in the Washington, D.C. area. Your health and wellness are our priority 🌿
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11/23/2023

Positive Outcomes Achieved with Mistletoe Therapy for Prostate Cancer (at NIHA clinic).

11/22/2023

11/10/2023

08/08/2023

Candida Infection's Potential Link to Colorectal Cancer

Colorectal cancer, a significant global health concern, is influenced by factors like age, genetics, and lifestyle [1]. Emerging research explores the possible connection between Candida infections and colorectal cancer. Candida, a common fungus in the body, can become problematic when it overgrows, possibly contributing to cancer development.

Candida species naturally inhabit the body, but their unchecked growth can lead to infections. Candida albicans, Candida glabrata, and Candida tropicalis are common culprits. These infections, termed candidiasis, range from superficial conditions to severe cases in individuals with weakened immunity.

Research into the gut microbiota's role in health is gaining traction. Imbalances, called dysbiosis, are linked to diseases including colorectal cancer [3]. Dysbiosis creates an inflammatory environment and disrupts the intestinal barrier, potentially facilitating cancer growth.

Candida infections are associated with inflammation in various tissues. Chronic gut candidiasis might sustain inflammation, fostering an environment favorable for colorectal cancer [2], [4]. Studies highlight how Candida could promote inflammation and tumor growth, but the exact relationship remains complex and requires further investigation.

While research hints at a connection between Candida infections and colorectal cancer, multiple factors influence cancer development. Understanding Candida's role alongside genetics and lifestyle is crucial. As research advances, insight into this intricate relationship could offer new strategies for cancer prevention and treatment [1].

Dr. Paymon Sadrolsadot ND, PhD

References:

1) Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144(5), 646-674.
2) Noverr, M. C., & Huffnagle, G. B. (2004). Does the microbiota regulate immune responses outside the gut?. Trends in microbiology, 12(12), 562-568.
3) Sokol, H., & Pigneur, B. (2018). Colorectal cancer in inflammatory bowel diseases: the role of the gut microbiota. Current Opinion in Gastroenterology, 34(1), 04-10.
4) Wu, S., Rhee, K. J., Albesiano, E., Rabizadeh, S., Wu, X, Yen, H. R., ... & Sears, C. L. (2009). A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nature Medicine, 15(9), 1016-1022.

07/29/2023

Breast Cancer and Vitamin D: What the Research Says

Breast cancer is a prevalent and life-altering disease that affects millions of women worldwide. Over the years, researchers have explored various factors that may influence breast cancer risk and outcomes. One such area of interest is the relationship between breast cancer and vitamin D deficiency. In this blog, we will delve into the existing research and shed light on the potential link between vitamin D and breast cancer[1].

Vitamin D and Breast Cancer Risk
Numerous studies have investigated whether vitamin D deficiency is associated with an increased risk of breast cancer. Vitamin D plays a critical role in various bodily processes, including cell growth regulation and immune function. Some research suggests that adequate vitamin D levels may have a protective effect against certain cancers, including breast cancer. While the evidence is not yet definitive, the association between vitamin D and breast cancer risk warrants further exploration[1].

Vitamin D and Breast Cancer Outcomes
In addition to its potential role in breast cancer risk, vitamin D status has also been examined in relation to breast cancer outcomes. Some studies have found that breast cancer patients with low vitamin D levels may face an increased risk of disease progression and a poorer overall survival rate compared to those with sufficient vitamin D levels. This suggests that optimizing vitamin D levels might play a role in improving breast cancer prognosis[2][3].

Mechanisms of Action
Vitamin D is believed to influence cell growth and differentiation, reduce inflammation, and support the immune system. These processes are crucial in cancer development and progression. However, further studies are needed to fully comprehend how vitamin D may impact breast cancer biology[2][4].

In conclusion, maintaining adequate vitamin D levels through appropriate supplementation, dietary choices, and exposure to sunlight remains important for overall health. If you have concerns about your vitamin D status or breast cancer risk, consult your healthcare provider for personalized guidance and screening.

Dr. Paymon Sadrolsadot ND, PhD

References:
[1]. Hossain S, Beydoun MA, Beydoun HA, et al. Vitamin D and breast cancer: a systematic review and meta-analysis of observational studies. Clin Nutr ESPEN. 2019;29:173-187.
[2]. Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer. 2007;7(9):684-700.
[3]. Mohr SB, Gorham ED, Kim J, et al. Meta-analysis of vitamin D sufficiency for improving survival of patients with breast cancer. Anticancer Res. 2014;34(3):1163-1166.
[4]. Yao S, Kwan ML, Ergas IJ, et al. Association of serum level of vitamin D at diagnosis with breast cancer survival: a case-cohort analysis in the Pathways study. JAMA Oncol. 2017;3(3):351-357.

07/08/2023

The Differences in Symptoms and Clinical Presentations: Candida vs. Mold Infections

Candida and mold infections, though both caused by fungi, have distinct differences in symptoms and clinical presentations. Recognizing these disparities is vital for accurate diagnosis and appropriate management. Let's delve into the contrasting features of Candida and mold infections.

Candida Infections:
Candida infections often involve mucous membranes, resulting in symptoms such as redness, itching, and discharge. Common sites include the mouth (oral thrush), ge****ls (vaginal yeast infection), and skin (cutaneous candidiasis) (1).

Mold Infections:
Mold infections primarily affect the respiratory system, leading to symptoms like coughing, wheezing, and nasal congestion. Mold exposure can also trigger allergic reactions, including runny nose, sneezing, and itchy eyes (2).

Systemic Involvement:
Candida infections can progress to systemic candidiasis, causing infections in the bloodstream or internal organs. This can lead to severe symptoms, including fever, fatigue, and organ dysfunction (3).

Invasive Mold Infections:
Invasive mold infections are more likely to occur in individuals with compromised immune systems. They can cause serious illnesses, such as invasive aspergillosis, which manifests as fever, chest pain, and coughing up blood (4).

Risk Factors:
Candida infections are more prevalent in individuals with weakened immune systems, whereas mold infections are often associated with exposure to mold-contaminated environments and respiratory conditions (5, 6).

So while Candida and mold infections share the commonality of being fungal infections, they exhibit distinct differences in symptomatology and clinical presentations. Recognizing these dissimilarities is crucial for accurate diagnosis and effective treatment.

References:

1) Centers for Disease Control and Prevention. (2019). Candidiasis. Retrieved from https://www.cdc.gov/fungal/diseases/candidiasis/index.html
2) World Health Organization. (2009). Guidelines for Indoor Air Quality: Dampness and Mould. Retrieved fromhttps://www.euro.who.int/__data/assets/pdf_file/0017/43325/E92645.pdf
3) Pappas, P. G., et al. (2018). Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases, 62(4), e1-e50.
4) Centers for Disease Control and Prevention. (2019). Mold. Retrieved from https://www.cdc.gov/mold/faqs.htm
5) Agarwal, R., et al. (2013). Allergic bronchopulmonary aspergillosis: Review of literature and proposal of new diagnostic and classification criteria. Clinical & Experimental Allergy, 43-8, 850-873.
6) American Academy of Allergy, Asthma & Immunology. (n.d.). Fungal Allergy. Retrieved from https://www.aaaai.org/conditions-and-treatments/allergies/fungal-allergy

06/30/2023

Vitamin D is a fat-soluble vitamin that plays a crucial role in maintaining bone health, immune function, and overall well-being.