OpenBiome

01/07/2026

2026 holds great promise thanks to the clinicians, researchers and funders who continue to advocate for innovative microbiome therapeutics for patients with Clostridioides difficile, an insidious disease of the gut. Together, we will continue to advance microbiome research, close the treatment gap for the most vulnerable and assure no patient is left behind.
https://openbiome.org/standing-together-with-gratitude-and-purpose/

11/21/2025

The Peggy Lillis Foundation’s Second Annual Scientific Conference brought clinicians, patients, researchers and scientists together to explore C. difficile, a debilitating gut infection that affects some 500,000 Americans annually. OpenBiome Foundation’s Chief Medical Advisor Majdi Osman, MD, MPH, presented on 𝐑𝐞𝐚𝐥-𝐖𝐨𝐫𝐥𝐝 𝐄𝐟𝐟𝐞𝐜𝐭𝐢𝐯𝐞𝐧𝐞𝐬𝐬 𝐚𝐧𝐝 𝐒𝐚𝐟𝐞𝐭𝐲 𝐨𝐟 𝐈𝐧𝐯𝐞𝐬𝐭𝐢𝐠𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐅𝐞𝐜𝐚𝐥 𝐌𝐢𝐜𝐫𝐨𝐛𝐢𝐨𝐭𝐚 𝐓𝐫𝐚𝐧𝐬𝐩𝐥𝐚𝐧𝐭𝐚𝐭𝐢𝐨𝐧. The presentation underscored the power of a centralized stool bank in overcoming barriers to access and in establishing the monitoring of safety and effectiveness of FMT in C. difficile infection across thousands of providers and patients.

11/05/2025

Majdi Osman, MD, MPH, Chief Medical Advisor, OpenBiome Foundation, will present on the "Safety of F***l Microbiota Transplantation for C. Difficile Infection: A Decade of Experience from a Large Nonprofit Stool Bank" at The Peggy Lillis Foundation 's Science Summit. Registration is now open (https://hubs.li/Q03HGRM80) for the virtual Summit that brings together clinicians, scientists and patients to explore the latest research and treatments for 𝘊𝘭𝘰𝘴𝘵𝘳𝘪𝘥𝘪𝘰𝘪𝘥𝘦𝘴 𝘥𝘪𝘧𝘧𝘪𝘤𝘪𝘭𝘦 (C. diff).

10/28/2025

We are proud to serve as an underwriter for The Peggy Lillis Foundation 's second annual Science Symposium on November 21. Please mark your calendars for this critical, in depth examination of the current status of C. diff research and treatment across the country.
https://openbiome.org/

𝐽𝑜𝑖𝑛 𝑢𝑠 𝑓𝑜𝑟 𝑜𝑢𝑟 𝑠𝑒𝑐𝑜𝑛𝑑 𝑎𝑛𝑛𝑢𝑎𝑙 𝑆𝑐𝑖𝑒𝑛𝑡𝑖𝑓𝑖𝑐 𝑆𝑦𝑚𝑝𝑜𝑠𝑖𝑢𝑚 𝑜𝑛 𝐹𝑟𝑖𝑑𝑎𝑦, 𝑁𝑜𝑣𝑒𝑚𝑏𝑒𝑟 21. 𝑇ℎ𝑖𝑠 𝑣𝑖𝑟𝑡𝑢𝑎𝑙 𝑒𝑣𝑒𝑛𝑡 𝑤𝑖𝑙𝑙 𝑎𝑙𝑙𝑜𝑤 𝑐𝑙𝑖𝑛𝑖𝑐𝑖𝑎𝑛𝑠, 𝑠𝑐𝑖𝑒𝑛𝑡𝑖𝑠𝑡𝑠, 𝑛𝑢𝑟𝑠𝑒𝑠, 𝑝ℎ𝑎𝑟𝑚𝑎𝑐𝑖𝑠𝑡𝑠, 𝑎𝑛𝑑 𝑖𝑛𝑑𝑢𝑠𝑡𝑟𝑦 𝑡𝑜 𝑖𝑛𝑡𝑒𝑟𝑚𝑖𝑛𝑔𝑙𝑒 𝑎𝑛𝑑 𝑢𝑝𝑑𝑎𝑡𝑒 𝑒𝑎𝑐ℎ 𝑜𝑡ℎ𝑒𝑟 𝑑𝑢𝑟𝑖𝑛𝑔 𝐶. 𝑑𝑖𝑓𝑓 𝐴𝑤𝑎𝑟𝑒𝑛𝑒𝑠𝑠 𝑀𝑜𝑛𝑡ℎ. 𝑇ℎ𝑒 𝑆𝑦𝑚𝑝𝑜𝑠𝑖𝑢𝑚 𝑤𝑖𝑙𝑙 𝑎𝑙𝑠𝑜 𝑓𝑒𝑎𝑡𝑢𝑟𝑒 𝑡𝑒𝑠𝑡𝑖𝑚𝑜𝑛𝑖𝑎𝑙𝑠 𝑓𝑟𝑜𝑚 𝐶. 𝑑𝑖𝑓𝑓 𝑝𝑎𝑡𝑖𝑒𝑛𝑡𝑠 𝑎𝑛𝑑 𝑠𝑢𝑟𝑣𝑖𝑣𝑜𝑟𝑠.

𝐼𝑛 𝑎𝑑𝑑𝑖𝑡𝑖𝑜𝑛 𝑡𝑜 𝑝𝑟𝑒𝑠𝑒𝑛𝑡𝑎𝑡𝑖𝑜𝑛𝑠 𝑏𝑦 𝑆𝑝𝑜𝑛𝑠𝑜𝑟𝑠, 𝑤𝑒 𝑎𝑟𝑒 𝑠𝑒𝑒𝑘𝑖𝑛𝑔 𝑢𝑝 𝑡𝑜 𝑒𝑖𝑔ℎ𝑡 𝑝𝑟𝑒𝑠𝑒𝑛𝑡𝑎𝑡𝑖𝑜𝑛𝑠 𝑓𝑟𝑜𝑚 𝑟𝑒𝑠𝑒𝑎𝑟𝑐ℎ𝑒𝑟𝑠 𝑎𝑛𝑑 𝑐𝑙𝑖𝑛𝑖𝑐𝑖𝑎𝑛𝑠. 𝑊ℎ𝑖𝑙𝑒 𝑤𝑒 𝑎𝑟𝑒 𝑝𝑎𝑟𝑡𝑖𝑐𝑢𝑙𝑎𝑟𝑙𝑦 𝑖𝑛𝑡𝑒𝑟𝑒𝑠𝑡𝑒𝑑 𝑖𝑛 𝑡𝑜𝑝𝑖𝑐𝑠 𝑠𝑢𝑐ℎ 𝑎𝑠 𝑖𝑛𝑓𝑒𝑐𝑡𝑖𝑜𝑛 𝑐𝑜𝑛𝑡𝑟𝑜𝑙, 𝑢𝑠𝑒 𝑜𝑓 𝑙𝑖𝑣𝑒 𝑏𝑖𝑜𝑡ℎ𝑒𝑟𝑎𝑝𝑒𝑢𝑡𝑖𝑐 𝑝𝑟𝑜𝑑𝑢𝑐𝑡𝑠 𝑖𝑛 𝑡ℎ𝑒 𝑡𝑟𝑒𝑎𝑡𝑚𝑒𝑛𝑡, 𝐶. 𝑑𝑖𝑓𝑓 𝑖𝑛 𝑜𝑡ℎ𝑒𝑟 𝑐𝑜𝑢𝑛𝑡𝑟𝑖𝑒𝑠 𝑎𝑛𝑑 𝑟𝑒𝑔𝑖𝑜𝑛𝑠, 𝑤𝑒 𝑎𝑟𝑒 𝑜𝑝𝑒𝑛 𝑡𝑜 𝑎𝑛𝑦 𝐶. 𝑑𝑖𝑓𝑓-𝑟𝑒𝑙𝑎𝑡𝑒𝑑 𝑡𝑜𝑝𝑖𝑐. 𝑇ℎ𝑒 𝑑𝑒𝑎𝑑𝑙𝑖𝑛𝑒 𝑓𝑜𝑟 𝑡𝑜𝑝𝑖𝑐 𝑠𝑢𝑏𝑚𝑖𝑠𝑠𝑖𝑜𝑛𝑠 𝑖𝑠 𝑆𝑒𝑝𝑡𝑒𝑚𝑏𝑒𝑟 15, 2025.

𝐿𝑒𝑎𝑟𝑛 𝑚𝑜𝑟𝑒, 𝑟𝑒𝑔𝑖𝑠𝑡𝑒𝑟, 𝑜𝑟 𝑠𝑢𝑏𝑚𝑖𝑡 𝑎 𝑡𝑜𝑝𝑖𝑐 ℎ𝑒𝑟𝑒: https://hubs.li/Q03HGRM80

09/29/2025

The Peggy Lillis Foundation ’s 16th Annual Gala brought out the stars for C diff patients. Dr. Stacy Kahn, attending Physician at Boston Children’s Hospital (third from left) was honored with a Leadership Award for her many firsts. She directed the nation’s first pediatric f***l microbiota transplant (or FMT) program, created the first national pediatric FMT registry, and performed the very first FMT for a child. She is joined by (left to right) Liam Lillis, Co-Founder and President of the Peggy Lillis Foundation, OpenBiome Foundation’s CEO Julie Barrett O’Brien and Christian John Lillis, Co-Founder and CEO of the Peggy Lillis Foundation. Dr. Kahn has worked tirelessly with OpenBiome and the Peggy Lillis Foundation to ensure children and medically complex patients retain access to life-changing f***l transplants.

09/10/2025

Food systems are teeming with complex microbial networks, carried from soil and water to crops, animals, and humans. Can we better track and steer these networks to enhance ecosystem health and food security?

Join CEO Julie O’Brien, OpenBiomeFoundation, at this webinar to hear an exploration of new thinking on enhancing health and food security with Prof Paul Cotter from Teagasc Ballyhaise College , VistaMilk SFI Research Centre , and SeqBiome , Dr Tanja Kostic from AIT Austrian Institute of Technology and Microbiome Support Association, Dr Paula Fernández Gómez from Universidad de León Mx , and Karel Callens from the Food and Agriculture Organization of the United Nations (FAO) .

Register now ➡️ https://fro.ntiers.in/NfcCnmIEkWb

How can scientists, innovators, regulators, educators, and everyday consumers unite to protect vital microbial communities? Register for this webinar to find out more https://events.frontiersin.org/agrifood-system-microbiomes/splash-share

08/20/2025

Can a holistic microbiome approach to the agri-food system address childhood malnutrition? Our policy outlook offers some thoughts.

08/19/2025

A privilege to join Frontiers in Science as a contributor with Paul Cotter and colleagues in an exploration of disentangling how microbiomes are interconnected across agri-food systems.

05/06/2025

Proud to share our CEO Julie Barrett O’Brien’s Harvard Kennedy School profile as a global champion for microbiome science and therapeutics for all.

As the CEO of nonprofit OpenBiome, Barrett O’Brien is advancing microbiome science and therapeutics to improve health for all.

05/04/2025

We’re proud to be at , standing shoulder to shoulder with gutsy pioneers, patients, and partners in gut health.

OpenBiome has always believed in the power of being gutsy -taking bold action to serve patients with C. Diff and accelerating the next wave of microbiome breakthroughs.

Let’s make this week about science with a soul.

05/02/2025

We’re heading to Digestive Disease Week (DDW) this weekend—and we’re bringing our boldest commitment with us: No C. diff patient left behind.

At OpenBiome, being gutsy means taking action where it matters most: supporting clinicians through the complexities of FMT and regulatory pathways; training hospitals to make in-house FMT accessible and sustainable; and powering a clinical study for patients with severe and fulminant C. diff.

If you're a clinician, researcher, or partner attending —and you’re committed to transforming C. diff care—we want to talk.

DM me or comment below if you’d like to connect in San Diego.

Let’s be gutsy, together.