Basic dermatology

13/04/2025

For the following pairs of collagen and their locations,which is incorrect?
A.type1 collagen_reticular dermis.
B.type 3 collagen_blood vessels and subepidermal region.
C.type 4 collagen_basement membrane zone and perivascular region.
D.type 2 collagen_cartilage.
E.type 7collagen_anchoring filamints.

12/04/2025

Langerhans cells:

A. Constitute 2 to 4 prsent of the total epidermal cell population.

B. Express immune response-associated antigens 1A and HLADR.

C. Exepress S100 protein.

D. They play an important role in contact sensitization.

e. All the above are true

12/04/2025

A 64-year-old woman who is reviewed due to multiple non-healing leg ulcers. She reports feeling
generally unwell for many months. Examination findings include a blood pressure of 138/72 mmHg,
pulse 90 bpm, pale conjunctivae and poor dentition associated with bleeding gums. What is the most
likely underlying diagnosis?

A. Thyrotoxicosis
B. Vitamin B12 deficiency
C. Vitamin C deficiency
D. Diabetes mellitus
E. Sarcoidosis

12/04/2025

11/04/2025

Which of the following requires parenteral replacement after gastrectomy?
A. Vitamin A
B. Vitamin D
C. Vitamin B12
D. Vitamin K
E. Iron

09/04/2025

7. Melanocytes can NOT be identified with which of the following stains?

A. Bloch dopa reaction.

B. Silver stains.

C. Fontane Masson stain.

D. Congo red.

09/04/2025

22 year- old man complaints of apperance of very painful unilateral erythema on the right flank. Aday later he developed multiple clear fluid filled blister at the same site. His doctor scrapes the base of afresh blister for microscopic examination. He is looking for:

a. Amodified keratinocyte

b. Neutrophilic infiltrate toexclude bacterial super- infection

C. Eosinophilic infiltrate to dignose insect bite.

d. Acantholytic cells to dignose autoimmune blistering disease.

09/04/2025

.A 55 ـ year- old lady presents
With flaccid bullae and slow- healing erosions on head and trunk. She also has painful oral erosions. She gives history of similar episode in past wich required treatment in hospital. the most likely structure damaged in the patient is :

a. Desmoplakin

b. Desmoglein3 of desmosomes

C. Desmoglein 3 of hemidesmosomes

d. Desmoglein1 of desmosomes

e. Desmogilin1 of hemidesmosomes

09/04/2025

All of the following are true about odland bodies Except :

a. They are discharged from the spinous cells into the intercellular space

b. They help establish abarrier to water loss.

C. They mediate stratum corneum adhesion.

d. They measure 300 to 500 nm in diameter.

08/04/2025

Regarding the basement membrane zone decide which of the following is FALSE:

A. The lamina lucida separate the trilaminar plasma membrane from the lamina densa

B. The upper lamina lucida contain the sub-basal cell dens plate

C. Anchoring fibrils extend from the hemidesmosomes of the basal cell plasma membrane to lamina lucida

D. The lamina lucida is 30 to 60 nm wide

E. Type 4 collagen is found within the lamina densa

08/04/2025

46- An elderly gentleman with metastatic colon cancer is prescribed erlotinib, an epidermal growth
factor receptor monoclonal antibody. What is the most common cutaneous finding seen as a result
of this class of medication?
A. Acneiform eruption
B. Acral erythema
C. Morbilliform eruption
D. Hypotrichosis
E. Urticaria

08/04/2025

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