Clinical Pharmacy

14/07/2025

https://www.youtube.com/watch?v=Xsk1mSY0AIo

The proteins inside your body play a crucial role in keeping you alive. But when cells lose control of specific proteins, serious diseases like cancer can em...

24/05/2024

Dosage adjustment requirements for direct acting oral anticoagulants with renal impairment:
https://www.the-hospitalist.org/hospitalist/article/173190/thrombosis/replacing-warfarin-noac-patients-chronic-anticoagulation

24/05/2024

Direct acting oral anticoagulants have several advantages over warfarin. In addition to those listed below, they are associated with lower incidence of osteoporosis.

18/03/2024

An interesting article shedding the light on the role of pharmacist in management of diabetes patients.
https://www.dovepress.com/getfile.php?fileID=34457

19/10/2023

Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss

https://jamanetwork.com/journals/jama/fullarticle/2810542

The study found increased risks of gastrointestinal adverse events (biliary disease, pancreatitis, bowel ‎obstruction, and gastroparesis) in patients with diabetes receiving glucagon-like peptide 1 (GLP-1) ‎agonists. These medications have also been used off label for weight loss. The study compared new ‎users of semaglutide or liraglutide, 2 main GLP-1 agonists, and the active comparator bupropion-‎naltrexone, a weight loss agent unrelated to GLP-1 agonists. The sample size was 16 million patients ‎‎(from the PharMetrics Plus database (IQVIA), a large health claims database that captures 93% of all ‎outpatient prescriptions and physician diagnoses in the US through the International Classification of ‎Diseases, Ninth Revision (ICD-9) or ICD-10.) ‎

This database study examines the association between glucagon-like peptide 1 agonists (eg, semaglutide, liraglutide) used for weight loss and reports of gastrointestinal adverse events.

30/06/2022

https://accpjournals.onlinelibrary.wiley.com/share/GACQFWECS4RZFNSUH46D?target=10.1592/phco.23.10.1153.32758

Pharmacist-managed clinics exist in many practice settings, such as physician offices, hospital-based outpatient clinics, and pharmacies. This article is intended to serve as a primer for pharmacists...

24/02/2022

The Centre for Adverse Reactions Monitoring (CARM) has received a report of a 63-year-old female who was taking 40 mg of citalopram daily. The patient experienced a ventricular tachycardia leading to cardiac arrest and was found to have a prolonged QT interval.

11/02/2022

https://www.facebook.com/694106927327014/posts/6966572463413731/

🗣 Shout out to University of Colorado faculty member Dr. Meghan Jeffres for this 📸 table and frankly all of her work, 🤩 I am a fan! …penicillin and cephalosporin cross reactivity depends on 🧩 shared side chains……..

29/12/2021

05/12/2021

Compared with the fasting condition, administration after a high-fat and high-calorie meal resulted in an approximately 40% reduction of rosuvastatin exposure and a near 50% decrease in absorption rate.

https://accp1.onlinelibrary.wiley.com/doi/epdf/10.1002/cpdd.706

28/10/2021

Fexofenadine should be taken on empty stomach with water. Taking it with high-fat meal decreased Cmax and AUC by about 50%

12/10/2021

Interesting article: Empagliflozin in heart failure
https://www.nejm.org/doi/full/10.1056/NEJMoa2022190

Original Article from The New England Journal of Medicine — Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure