28/07/2021
there's always something new that's good to know 💓
People with depression exhibit decreased brain serotonin (5-hydroxytryptamine, 5-HT) levels and function and elevated cortisol levels in the bloodstream. Serotonin deficits are often treated by selective serotonin reuptake inhibitors (SSRIs) drugs with significant side effects, such as weight gain, sexual dysfunction, insomnia, anxiety, agitation or restlessness, and stomach disorders.
An experimental model of depression evaluated whether basil essential oil could correct abnormal serotonin and cortisol levels in depressed subjects. The study compared serotonin levels in three groups: 1) control, non-depressed, 2) depressed, no treatment, and 3) depressed, oral administration of basil essential oil for four weeks. Oral administration of basil essential oil decreased cortisol in depressed subjects, however it didn't decreases levels fully back to normal. Remarkably, basil oil significantly increased serotonin levels, which exceeded that of the depressed (untreated) group and the normal group. The results suggest that basil essential oil may help support a healthy mood.
https://pubmed.ncbi.nlm.nih.gov/31777626/