Helpful Scientist

23/03/2026

Yogam Yoga

21/03/2026

16/03/2026

People often imagine science as one person in a lab coat.
But behind every diagnostic test result are dozens of people quietly making it possible.
Engineers. Field technicians. Logistics teams. Cleaners. Laboratory staff.
I wrote a story about the invisible workforce behind science.

https://open.substack.com/pub/kerushadoesscience/p/field-notes-of-a-helpful-scientist?utm_source=share&utm_medium=android&r=5l4obw

13/03/2026

Mental stress, either acute or chronic, produces certain physiological responses via the CNS. The body's adaptive responses to stress stimuli are mediated by an intricate system, which includes the hypothalamus-pituitary-adrenocortical (HPA) axis and the sympathoadrenal system. Dysregulation of the system by repetitive or chronic stress may induce continually increased adrenocortico-tropic hormone (ACTH) and corticosteroid levels, increase the production of monoamines and proinflammatory cytokines within the brain, and thus contribute to a variety of somatic and psychiatric disorders including hypertension, atherosclerosis, functional disorders of the digestive system, several immunological disorders, affective disorders, or anxiety.

From a clinical point of view, much evidence has accumulated that disturbances in the HPA axis with elevated circulating plasma levels of ACTH and Cortisol play a pivotal role in depression. As it is also known that administered corticosteroids induce hypercholesterolemia, hypertriglyceridemia, and hypertension and that elevated morning Cortisol concentrations are correlated with coronary artherosclerosis, a relationship between depression and vascular diseases seems plausible. However, in recent years, a paradoxical phenomenon has emerged from neurobiological studies on the effect of chronic stress, as a number of studies have provided evi dence that the adrenal gland is hypoactive in some stressrelated states, resulting in hypocortisolism.
This enhanced negative feedback sensitivity of glucocorticoid receptors or a persistent lack of Cortisol availability can be observed in posttraumatic stress disorder and in other conditions such as chronic fatigue syndrome, fibromyalgia (FM), and rheumatoid arthritis. It was proposed that traumatized or chronically stressed individuals may have an increased vulnerability for stress-related somatic disorders. In case you want to explore more, read my articles here: https://www.patreon.com/betterbrain

Reference: Bondy B. (2003)

13/03/2026

Science rarely looks like the movies.
It’s not always the big discoveries or the dramatic moments.
Most of the time it looks like:
Early mornings in quiet laboratories.
Hands carefully labelling tubes.
Machines humming in the background.
People double-checking results long after everyone else has gone home.
Behind every diagnosis, every treatment, every answer someone receives…
there is a chain of invisible people who made sure the science was done properly.
Technologists.
Scientists.
Quality managers.
Sample couriers.
People who care enough to get the details right.
These are the quiet guardians of truth.
Yesterday I shared a new story about what science really looks like behind the scenes.
If you enjoy honest stories from the field — the real ones, the funny ones, and the ones that remind us why this work matters — you can read the full piece here.
🔬 Field Notes from a Helpful Scientist
Link in comments.
– Kerusha

https://open.substack.com/pub/kerushadoesscience/p/field-notes-from-a-scientist-4?utm_source=share&utm_medium=android&r=5l4obw

02/03/2026

Join our KZN Branch for a powerful day of health, education and community care🌸

📅 Date: Saturday, 28 March 2026
⏰ Time: 10h00 – 14h00
📍 Venue: Gospel Outreach Assembly, 180 Moorcross Drive, Moorton, Chatsworth
Contact: Sharon Paul – 083 274 9420

PinkDrive, Mediskills and Helpful Science will be in attendance on the day.
Services Offered:
• Breast examinations & education
• One-on-one sessions with a nurse
• Educational health talk
• Blood pressure testing
• Glucose testing
• HIV/AIDS services
• An insightful gut health talk by Helpful Science

23/02/2026

Wishing you a wonderful week ahead 🥰🥰🥰

23/02/2026

💛🌿
✨ MENOPAUSE: The Plot Twist No One Prepared Us For ✨
Hot flashes at 2am.
Why am I in the fridge again?
Who moved my keys? (They’re in your hand.)
But here’s something surprising…
🧠 During menopause, your brain is actually rewiring itself.
Estrogen doesn’t just affect periods — it affects memory, temperature control, sleep, mood and even how your brain uses energy.
That fog?
That overheating?
That emotional sensitivity?
It’s not weakness.
It’s biology adjusting.
And here’s the hopeful part 💛
For most women, the brain adapts.
Sleep improves.
Mood stabilises.
Clarity returns.
This is not the end of you.
It’s a recalibration.
At Helpful Scientist, we believe menopause should be explained — not whispered about.
With facts.
With humour.
With compassion.
If you need support, guidance, or just someone to say “You are not crazy — your hormones are shifting,” we’re here 🌿