27/10/2025
CD4 vs Viral load
Quite a number of people living with HIV don't understand the difference. Some think they are one and the same thing. Some think CD4 indicates that they are responding well to treatment. Well let me give you the differentiation.
CD4 and viral load are both measured using a blood test, but they measure different things: a CD4 count measures the number of immune cells also known as helper T cells that fights infection. Generally a healthy CD4 should be between 500-1500 cells. A viral load test on the other hand measures the amount of HIV in the blood. Ideally, CD4 should be high and viral load should be low (preferably undetectable).
Initially CD4 count used to be used as a measure of how one was responding to treatment. But after research, scientists discovered that Viral load was actually the one that was able to give a clear picture of how well one was responding to treatment. So if you want to know if you are responding well to treatment, don't look at the CD4 count but look at your viral load. That is the true reflection of how well you are responding to treatment.