Entrance for Medical

Entrance for Medical This program is to equip the students before entering the exam and it includes almost all the necessary material and human medicine.

17/01/2015

Browse hotel, tours, packages and find the guaranteed best price for all budgets.

02/12/2014
01/12/2014
01/12/2014
01/12/2014

The five-year survival rate for advanced-stage laryngeal cancer was higher than national levels in a small study at a single academic center performing a high rate of surgical therapy, including a total laryngectomy (removal of the voice box), to treat the disease, despite a national trend toward organ preservation, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

The larynx is a common site of head and neck cancer with more than 10,000 cases annually. Over the past two decades, treatment for advanced-stage laryngeal cancer has shifted from primary surgical therapy to organ preservation treatments with chemotherapy and radiation, according to study background.

Blake Joseph LeBlanc, M.D., of Louisiana State University Health-Shreveport (LSU Health), and co-authors examined survival rates at their institution for primary surgical treatment of advanced-stage tumor with outcomes in the National Cancer Database (NCDB).

In an analysis of 165 patients (majority male, average age 55 years) with laryngeal cancer in the LSU Health tumor registry from 1998 to 2007, 48 (29.09 percent) had clinically early-stage (I/II) disease and 117 (70.91 percent) had advanced-stage (III/IV) disease. Of the 117 patients with advanced-stage disease, 64 (54.70 percent) underwent primary surgical therapy to include total laryngectomy or pharyngolaryngectomy (removal of the voice box and area at the back of the mouth and throat). Data from the NCDB shows the national rate of laryngectomy declined from 60 percent in the 1980s to 32 percent in 2007. At LSU Health, five-year survival for stage IV was 55.54 percent compared with 31.60 percent nationally. LSU Health's overall survival at all stages rate was 59.14 percent and similar to the nationwide rate, according to the study results.

"This study shows that LSU Health treats a high percentage of patients with advanced-stage laryngeal carcinoma who have lower socioeconomic status, yet still has improved survival rates compared with the NCDB over the study time period. This contributes to a growing body of literature that suggests that initial surgical therapy for advanced-stage disease may result in increased survival compared with organ preservation,"

30/11/2014

This program is to equip the students before entering the exam and it includes almost all the necessary material and human medicine.

DRUG TARGET IDENTIFIED FOR PREVENTION OFSTROKE RELATED BRAIN DAMAGE:A mechanism implicated in the brain damage experienc...
29/11/2014

DRUG TARGET IDENTIFIED FOR PREVENTION OFSTROKE RELATED BRAIN DAMAGE:

A mechanism implicated in the brain damage experienced by stroke patients has been identified by researchers from the University of Leeds in the UK and Zhejiang University in China. The scientists are now looking for effective drug therapies to prevent this damage.
When someone has a stroke, the blood supply to part of their brain is cut off. As the blood supply resumes in the brain in the days following the stroke, "oxidative stress" can damage the memory and cognitive function of the patient.
The researchers behind the new study say that, up until now, most of the research into potential drug therapies to treat stroke-related brain damage has focused on the initial damage caused by the loss of blood flow, rather than the damage from oxidative stress. However, this initial damage is hard to target.
"The patient may not even be in the ambulance when it is happening," says co-author Dr. Lin-Hua Jiang, of the University of Leeds' School of Biomedical Sciences. "We have found a mechanism that is linked to the next phase of damage that will often be underway after patients have been admitted to the hospital."
Ion channel reduces brain damage, if disabled
Studying the oxidative stress phase of stroke-related brain damage in a mouse model, the team found a mechanism in neurons that - if removed - reduces the level of damage.
Dr. Jiang explains:
"We identified an 'ion channel' in the membranes of neurons, called TRPM2, which is switched on in the presence of the reactive oxygen species. Basically, an ion channel is a door in the membrane of a cell that allows it to communicate with the outside world. TRPM2 opens when the harmful levels of reactive oxygen species are present and we found that removing it significantly reduced neuronal cell damage."
Investigating this ion channel further, the team compared the effects of stroke in mice with active TRPM2 and in those with inactivated TRPM2. They found that neurons were better protected from the oxidative stress in mice that had a disabled TRPM2 channel.
"The neuronal death is significantly reduced," says Dr. Jiang. "More importantly, we observed a significant difference in brain function, with the protected mice demonstrating significantly superior memory in lab tests."
The researchers believe they have pinpointed "a very promising drug target." Next, they will screen a large database of chemicals to find a way of inhibiting the TRPM2 channel. The team will continue testing in animal models to see how effective blocking TRPM2 is for protecting against brain damage and cognitive dysfunction following a stroke.
In May, Medical News Today reported on a study from researchers at Ohio State University Wexner Medical Center, which suggested that a daily dose of vitamin E could prevent or reduce brain damage from stroke.
The Ohio State researchers were particularly interested in tocotrienol - a type of vitamin E found in palm oil that reduces cholesterol. They found that tocotrienol increased the diameter of arteries in response to oxygen demand - an effective means of preventing brain damage.

The heart is an amazing muscle. For reasons described on this previous blog, “The Anatomy And Heart Function“, I am cons...
26/11/2014

The heart is an amazing muscle. For reasons described on this previous blog, “The Anatomy And Heart Function“, I am constantly marveling at all the complex elements that makes the heart operate. Interestingly enough…

Electricity has a lot to do with the actual starts and stops (aka contractions) in the cardiac conduction system. That said I thought you might like to see a diagram of cardiac conduction system.

26/11/2014

Share our application links,its so useful for medical students.

Two expat doctors have been acquitted of charges that they caused a Qatari woman to go blind and become paralysed, accor...
26/11/2014

Two expat doctors have been acquitted of charges that they caused a Qatari woman to go blind and become paralysed, according to Arabic daily Arrayah.
The brother of the patient had alleged that a Jordanian consultant physician and a Sudanese doctor working at Hamad General Hospital had caused the woman’s condition to deteriorate through negligence.
The woman was twice taken to the hospital complaining of severe stomach pain and was sent home with medication on both occasions, according to the brother.
When she continued to complain of pain, he told the court he took her to a private clinic. Following tests, the clinic referred her to the hospital for immediate surgery.
However, the hospital doctors again gave her medication and said the surgery would be done only if her condition did not improve.
Eventually, her condition worsened and she underwent the surgery, which was not successful, Arrayah said.
A forensic medical report carried out for the court could not determine if the outcome was a result of negligence by delaying the surgery or a normal development of her illness.
The doctors pleaded not guilty to the charges and were acquitted.

Address

MAMZAR, DUBAI
Dubai

Alerts

Be the first to know and let us send you an email when Entrance for Medical posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Entrance for Medical:

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram