17/12/2025
: Treatment of Severe Low Back Pain with Lumbar Medial Branch Cryoneurolysis
A 65-year-old female patient was presented with severe low back pain refractory to conservative treatment for approximately one year, including various analgesic medications and multiple physical therapy sessions. At the presentation, the Visual Analog Scale (VAS) score was 9.
Lumbar imaging demonstrated disc protrusions at the L2–3 and L3–4 levels, more pronounced on the left side. The patient reported bilateral pain, predominantly on the left, causing significant difficulty with mobility and sleep.
The procedure was performed under local anesthesia with the patient in the prone position, using combined ultrasound and fluoroscopic guidance. A 16-G cryoprobe with a length of 12 cm was advanced to the medial branch target. Cryoneurolysis was performed using carbon dioxide (CO₂), achieving a temperature of −88 °C, applied in two cycles of 2 minutes each, creating an approximately 7-mm ice ball. Bilateral cryoneurolysis was applied to the medial branches at the L3 vertebral level, and unilateral cryoneurolysis was applied to the left medial branch at the L4 level.
The patient experienced a noticeable reduction in pain during the procedure.
She was discharged ambulatory with significant pain relief. The post-procedural VAS score was 2.
Case courtesy: Mehmet Fatih İnecikli, Serhat Akış