CeMM

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences At the center of CeMM’s interest are patients and associated diseases.

CeMM integrates basic research and clinical expertise to pursue innovative diagnostic and therapeutic approaches focused on cancer, inflammation and immune disorders.

🎓 Congratulations to Bernhard Ransmayr, from the group of Adjunct Principal Investigator Kaan Boztug (Universitätsklinik...
20/02/2026

🎓 Congratulations to Bernhard Ransmayr, from the group of Adjunct Principal Investigator Kaan Boztug (Universitätsklinikum Bonn, St. Anna Kinderkrebsforschung, and Medizinische Universität Wien), on successfully defending his PhD thesis entitled "Lymphotoxin Beta Receptor Deficiency Expands the Spectrum of NF-κB Related Inborn Errors of Immunity."

During his PhD, he characterized the first patients with mutations in the lymphotoxin beta receptor (LTβR), who lacked lymph nodes and had impaired immune function. His work demonstrated that LTβR signaling is essential for secondary lymphoid organ development and the proper functioning of the human immune system.

Well done, Bernhard! Your colleagues and friends at CeMM are proud of you! 🎉👏

📸 Barbara Bachmann / CeMM

🧬 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗴𝗹𝘂𝗲 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗮𝘁 𝘀𝗰𝗮𝗹𝗲: 𝗳𝗿𝗼𝗺 𝗰𝗵𝗮𝗻𝗰𝗲 𝘁𝗼 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝘆Targeted protein degradation has opened new therapeutic poss...
16/02/2026

🧬 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗴𝗹𝘂𝗲 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗮𝘁 𝘀𝗰𝗮𝗹𝗲: 𝗳𝗿𝗼𝗺 𝗰𝗵𝗮𝗻𝗰𝗲 𝘁𝗼 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝘆

Targeted protein degradation has opened new therapeutic possibilities for proteins long considered undruggable. A new study by the teams of Georg Winter at CeMM and AITHYRA, and Michael Erb at The Scripps Research Institute, introduces a large-scale, systematic strategy to discover molecular glues, small molecules that trigger the selective degradation of disease-causing proteins.

Instead of relying on chance discoveries, the researchers combined high-throughput chemistry with cell-based functional testing to generate and screen thousands of compounds directly in living cells. As a proof of concept, they focused on ENL, a protein that plays a key role in certain forms of aggressive leukemia. Their approach enabled the rapid identification of molecules that induce ENL degradation in leukemia cells.

Their work, published in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘊𝘩𝘦𝘮𝘪𝘤𝘢𝘭 𝘉𝘪𝘰𝘭𝘰𝘨𝘺, could transform molecular glue discovery into a scalable process and open new avenues for therapies targeting previously inaccessible proteins.

➡️ Read more: https://bit.ly/4re95Wu
📄 Publication: https://go.nature.com/4aBzBSD

📸 Co-first author Miquel Muñoz i Ordoño and co-senior author Georg Winter (© CeMM / AITHYRA).

📸 Figure: Molecular structure of the leukemia protein ENL in the degradation complex introduced by the molecular glue dHTC1 (© Miquel Muñoz i Ordoño).

16/02/2026

𝗛𝗮𝗽𝗽𝘆 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗗𝗮𝘆!💡 At CeMM, we are constantly striving to create & maintain an entrepreneurial environment that transforms innovative ideas into solid projects & even new companies.

🔎 Innovation & Tech Transfer at CeMM in a nutshell:
📍 20 patent families
📍 4 trademarks
📍 Founding partner of 6 spin-offs

Find out more ➡️ https://bit.ly/46vVkKh

Are you interested in partnering, licenses, or know-how agreements? 🤝
✉️ Contact CeMM Tech Transfer Officer Pedro Lopes at IP@cemm.at

🚀 𝗕𝘂𝗶𝗹𝗱𝗶𝗻𝗴 𝗕𝗲𝘁𝘁𝗲𝗿 𝗦𝗰𝗶𝗲𝗻𝗰𝗲: Yesterday, we hosted the 𝗖𝗲𝗠𝗠 𝗪𝗼𝗺𝗲𝗻 𝗶𝗻 𝗦𝗰𝗶𝗲𝗻𝗰𝗲 𝗗𝗮𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟲, an inspiring, highly inter...
12/02/2026

🚀 𝗕𝘂𝗶𝗹𝗱𝗶𝗻𝗴 𝗕𝗲𝘁𝘁𝗲𝗿 𝗦𝗰𝗶𝗲𝗻𝗰𝗲: Yesterday, we hosted the 𝗖𝗲𝗠𝗠 𝗪𝗼𝗺𝗲𝗻 𝗶𝗻 𝗦𝗰𝗶𝗲𝗻𝗰𝗲 𝗗𝗮𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟲, an inspiring, highly interactive afternoon bringing together scientists and administrative staff from PhD students to postdocs and P*s, across all genders. We came together with a shared commitment to strengthening our research culture through open dialogue and forward-looking ideas. From keynote and impulse talks to thematic breakout discussions and a closing reflection, the program created space for honest exchange and practical strategies for change.

The symposium opened with keynote speaker 𝗨𝗹𝗿𝗶𝗸𝗲 𝗙𝗲𝗹𝘁, Professor at the Department of Science and Technology Studies at the Universität Wien, who captivated the audience with personal insights, reflections on science governance, and concrete ideas for institutional change.

We then heard diverse and powerful career journeys:

📍 𝗦𝘆𝗹𝘃𝗶𝗮 𝗞𝗻𝗮𝗽𝗽, Head of the Research Division Infection Biology at Medizinische Universität Wien, spoke about leadership, resilience, and structural challenges for women in science.

📍 𝗕𝗿𝗶𝗮𝗻𝗱𝗮 𝗦𝗮𝗻𝘁𝗶𝗻𝗶, former CeMM project scientist now at NVIDIA in AI-driven drug discovery, reflected on navigating male-dominated fields and the importance of women mentoring women.

📍 𝗔𝗻𝗻𝗲 𝗠𝗶𝗹𝗹𝗲𝗿, Junior Principal Investigator at MedUni Vienna, gave insights into establishing an independent research group in a field still largely led by men.

📍 𝗗𝗼𝗿𝗶𝘀 𝗖𝗵𝗲𝗻, bioinformatics data analyst at the Max Perutz Labs, combined her career story with practical advice for women in science navigating challenges.

📍 𝗚𝗶𝗼𝗿𝗴𝗶𝗮 𝗚𝗿𝗲𝘁𝗲𝗿, microbiologist and biotech co-founder, described her transition from research to entrepreneurship.

📍 𝗔𝗻𝗶𝘁𝗮 𝗘𝗻𝗱𝗲𝗿, Managing Director of CeMM and AITHYRA, shared her journey to leading two scientific institutions, showing how determination and vision can help us reach our goals.

Participants then joined rotating small-group panels to discuss authorship and recognition; work–life balance; postdoc, tenure, and management pathways; and impostor syndrome, fostering honest, cross-generational dialogue.

The symposium concluded with Flora Petrik, research fellow and lecturer at the Institute of Education at the Eberhard Karls Universität Tübingen, who shared her research on first-generation academics and offered important perspectives on social inequality in higher education.

Thank you to all speakers, participants, and organizers, Amelie Nagel, Michael Schöber, Katja Sommer, Hanna Toth, and Ariadna Villanueva, for making this event both inspiring and action-oriented. Together, we are building better science for all.

👉 View the photo gallery here: https://bit.ly/3M71UQJ

📸 Franzi Kreis / CeMM

𝗢𝗻 #𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆𝟭𝟭, 𝘄𝗲 𝗰𝗲𝗹𝗲𝗯𝗿𝗮𝘁𝗲 𝘁𝗵𝗲 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗗𝗮𝘆 𝗼𝗳 𝗪𝗼𝗺𝗲𝗻 𝗮𝗻𝗱 𝗚𝗶𝗿𝗹𝘀 𝗶𝗻 𝗦𝗰𝗶𝗲𝗻𝗰𝗲! 👩🏻‍🔬👩‍🔬At CeMM, women contribute acro...
11/02/2026

𝗢𝗻 #𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆𝟭𝟭, 𝘄𝗲 𝗰𝗲𝗹𝗲𝗯𝗿𝗮𝘁𝗲 𝘁𝗵𝗲 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗗𝗮𝘆 𝗼𝗳 𝗪𝗼𝗺𝗲𝗻 𝗮𝗻𝗱 𝗚𝗶𝗿𝗹𝘀 𝗶𝗻 𝗦𝗰𝗶𝗲𝗻𝗰𝗲! 👩🏻‍🔬👩‍🔬

At CeMM, women contribute across every level, team, and role, from science to administration. We deeply value their expertise, commitment, and curiosity; they are key to our success and truly embody the CeMM spirit.

Today and every day, we warmly thank all the women at CeMM for their passion and dedication. Together, we help shape CeMM as a leading research institute, advancing knowledge and innovation for all!

📸 Wolfgang Däuble / CeMM

What better way to start the week than with a new by Matthew Disney from The Wertheim UF Scripps Institute, hosted by ...
09/02/2026

What better way to start the week than with a new by Matthew Disney from The Wertheim UF Scripps Institute, hosted by Georg Winter, Stefan Kubicek, and the SCP3 organizers.

In his lecture, “Sequence-based design of small molecules targeting RNA structure”, Matthew shared how his lab applies evolutionary principles to identify molecular recognition patterns between small molecules and RNA structures. Using computational tools, they mine these patterns across the human transcriptome to define cellular RNAs that can be targeted.

He also highlighted recent advances from his team, including chimeras that combine an inactive small molecule with a ribonuclease-recruiting component to selectively degrade disease-causing RNAs. This offers a way to reprogram existing protein-targeting medicines for RNA.

Matthew Disney's lab focuses on deciphering how small molecules recognize RNA, and he has pioneered a bottom-up approach to identify RNA structures and design highly selective compounds that target disease-causing RNAs, work that earned him the Eli Lilly Award in Biological Chemistry.
His team developed foundational tools, including Two-Dimensional Combinatorial Screening and the StARTS analytical method to map RNA. Their efforts have also yielded some of the most selective RNA‑binding small molecules known, including agents that modulate microRNAs implicated in cancer, neurological disorders, addiction, and viral infections.

Thank you, Matthew, for a truly inspiring and forward-looking seminar on chemical biology!

📸 Wolfgang Däuble / CeMM

04/02/2026

📢 𝗧𝗵𝗲 𝗖𝗲𝗠𝗠 𝗣𝗿𝗲-𝗘𝗥𝗖 𝗣𝗼𝘀𝘁𝗱𝗼𝗰 𝗣𝗿𝗼𝗴𝗿𝗮𝗺 𝗖𝗮𝗹𝗹 𝗶𝘀 𝗻𝗼𝘄 𝗼𝗽𝗲𝗻!

Are you eager to pursue groundbreaking medical research and prepare yourself for an independent career in a top research organization? 𝗝𝗼𝗶𝗻 𝘁𝗵𝗲 𝗣𝗿𝗲-𝗘𝗥𝗖 𝗣𝗼𝘀𝘁𝗱𝗼𝗰 𝗣𝗿𝗼𝗴𝗿𝗮𝗺 𝗮𝘁 𝗖𝗲𝗠𝗠, designed to nurture the next generation of scientific leaders!

🔬 Based at CeMM, one of Europe’s leading centers for basic biomedical research with a strong focus on clinical translation, postdocs join CeMM research groups for 3–6 years to pursue ambitious, medically relevant research across fields such as cancer, immunology, chemical biology, epigenetics, metabolism, genomic medicine, and aging. The program also offers extensive career development and leadership training in a highly collaborative and supportive environment, along with opportunities for close interaction with physicians and clinical researchers, and for collaboration with industry (biotech/pharma).

Our partners include the Medizinische Universität Wien, St. Anna Children's Cancer Research Institute (CCRI), and AITHYRA Research Institute for Biomedical Artificial Intelligence, the newly founded research institute of the Austrian Academy of Sciences.

🔎 Research areas and concrete projects include:
📍 AI-powered research agents for bioinformatics and bioengineering (Bock Lab)
📍 Tissue immunology, immunotherapy, cell engineering, and/or synthetic biology (Bock Lab)
📍 Condensates, chromatin, and translational control in pediatric cancer (Grebien Lab)
📍 Linking nucleotide metabolism to chromatin biology (Kubicek Lab)
📍 Microbiota dysbiosis, increased gut permeability, and unhealthy aging (Rescigno Lab)

🗓️ 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗱𝗲𝗮𝗱𝗹𝗶𝗻𝗲: 𝟴 𝗠𝗮𝗿𝗰𝗵 𝟮𝟬𝟮𝟲, 𝟭𝟭:𝟱𝟵 𝗽𝗺 𝗖𝗘𝗧
🔗 Find out more and apply now: https://bit.ly/4rvURjt

❔ Curious to learn more?
𝗝𝗼𝗶𝗻 𝗼𝘂𝗿 𝗼𝗻𝗹𝗶𝗻𝗲 𝗼𝗽𝗲𝗻 𝗱𝗮𝘆 𝗼𝗻 𝟭𝟴 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆 𝟮𝟬𝟮𝟲, either at 10:00 am or 5:00 pm (CET). Register here for your preferred slot ➡️ https://bit.ly/4bv3TIJ

📣 Our CeMMinars are back! For the first seminar of the year, we had the pleasure of welcoming David Masopust from the Un...
29/01/2026

📣 Our CeMMinars are back! For the first seminar of the year, we had the pleasure of welcoming David Masopust from the University of Minnesota Medical School to CeMM. The session, focused on Memory CD8 T Cells, was hosted by CeMM Principal Investigator Clarissa Campbell and Adjunct Principal Investigator Andreas Bergthaler (MedUni Vienna).

During his talk, David Masopust shared insights from his pioneering work on T cell immune surveillance, migration, and memory, including tissue-resident memory T cells and their role in immunity and immunotherapy.

David is a McKnight Distinguished University Professor in the Department of Microbiology and Immunology at the University of Minnesota Medical School (US). He has developed innovative techniques for studying T cells in non-lymphoid tissues and vaccine strategies aimed at enhancing memory T cell populations. His research continues to advance our understanding of T cell biology and its applications in disease prevention and treatment.

Thank you, David, for launching our seminar series with such an insightful presentation!

📸 Barbara Bachmann / CeMM

CeMM was well represented at the 11th Wiener Ball der Wissenschaften - Vienna SciBall with its current members, and also...
25/01/2026

CeMM was well represented at the 11th Wiener Ball der Wissenschaften - Vienna SciBall with its current members, and also many former CeMMies. We are grateful to the Alumni Board that used the ball also for a gathering of CeMM Alumnae/Alumni. The Science Ball became a highly regarded tradition in our community. We had fun, we danced, we laughed, we met people we had missed, we made new contacts, we were inspired and forged new plans.

Thank you again, Oliver Lehmann, for giving our profession such a special event!

CeMM picture gallery: https://bit.ly/3NNxH9w

📢 𝗙𝗶𝗻𝗮𝗹 𝗱𝗮𝘆𝘀 𝘁𝗼 𝗮𝗽𝗽𝗹𝘆 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗔𝗜𝗧𝗛𝗬𝗥𝗔–𝗖𝗲𝗠𝗠 𝗝𝗼𝗶𝗻𝘁 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗣𝗵𝗗 𝗖𝗮𝗹𝗹!𝟭𝟱–𝟮𝟬 𝗳𝘂𝗹𝗹𝘆 𝗳𝘂𝗻𝗱𝗲𝗱 𝗣𝗵𝗗 𝗳𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽𝘀 are available...
23/01/2026

📢 𝗙𝗶𝗻𝗮𝗹 𝗱𝗮𝘆𝘀 𝘁𝗼 𝗮𝗽𝗽𝗹𝘆 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗔𝗜𝗧𝗛𝗬𝗥𝗔–𝗖𝗲𝗠𝗠 𝗝𝗼𝗶𝗻𝘁 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗣𝗵𝗗 𝗖𝗮𝗹𝗹!

𝟭𝟱–𝟮𝟬 𝗳𝘂𝗹𝗹𝘆 𝗳𝘂𝗻𝗱𝗲𝗱 𝗣𝗵𝗗 𝗳𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽𝘀 are available in Vienna, Austria 🇦🇹

Would you like to work on an exciting research project to address real-world problems in interdisciplinary computational, biomedical, clinical, and health research settings?

We offer:
✅ 4 years funding and employment contract (includes research costs and health insurance).
✅ A highly interactive introductory training program in a supportive peer-group environment.
✅ Full access to state-of-the-art technologies.
✅ Supervision by top scientists and support of the Faculty of either CeMM or AITHYRA.
✅ A PhD degree awarded by the Medizinische Universität Wien, the Technische Universität Wien or Universität Wien.
✅ An international program in the heart of a scientifically active and culturally vibrant European city.
✅A dynamic and highly multidisciplinary international research environment.

👉 𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲 𝗮𝗻𝗱 𝗮𝗽𝗽𝗹𝘆 𝗯𝘆 𝟯𝟬 𝗝𝗮𝗻𝘂𝗮𝗿𝘆 𝟮𝟬𝟮𝟲 ➡️ https://apply.cemm.at

🎓New year, new CeMM doctors!Congratulations to Katja Knapp, from the group of CeMM PI and MedUni Vienna Prof. Georg Star...
20/01/2026

🎓New year, new CeMM doctors!

Congratulations to Katja Knapp, from the group of CeMM PI and MedUni Vienna Prof. Georg Stary, on successfully defending her PhD thesis on "Preventive strategies and early immune responses in Chlamydia trachomatis infection".

During her PhD studies, she focused on the sexually transmitted pathogen 𝘊𝘩𝘭𝘢𝘮𝘺𝘥𝘪𝘢 𝘵𝘳𝘢𝘤𝘩𝘰𝘮𝘢𝘵𝘪𝘴. Her research addressed two complementary areas: first, investigating how the local immune system of the human female ge***al tract orchestrates immune responses against 𝘊𝘩𝘭𝘢𝘮𝘺𝘥𝘪𝘢; and second, developing novel strategies to prevent future chlamydial infections, including drug formulations suitable for application to the ge***al tract.

Your colleagues and friends at CeMM are proud of you, Katja. Well done! 🎉👏

📸 Wolfgang Däuble / CeMM

15/01/2026

Waltz steps, a bit of counting, and lots of concentration. We are getting into the rhythm for the Wiener Ball der Wissenschaften - Vienna SciBall 2026! 💃🏽🕺

CeMMies have kicked off dance practice to prepare for the big night next week. Here’s a sneak preview, great moves, keep it up!

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1090

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+43 1 40160 70011

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About CeMM

CeMM’s mission is to achieve maximum scientific innovation in molecular medicine to improve healthcare.

At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment of outstanding medical tradition and practice.

CeMM’s research is based on post-genomic technologies and focuses on societally important diseases, such as immune disorders and infections, cancer and metabolic disorders.

CeMM operates in a unique mode of super-cooperation, connecting biology with medicine, experiments with computation, discovery with translation, and science with society and the arts.