28/01/2026
When an entrepreneur says: βI canβt focus.β βMy motivation is gone.β βMy brain feels fried.β βIβm anxious but wired.β
I analyse their neurotransmitter pathways via genetic testing
Here are some key markers I assess in the Neurotransmitter section of DNA testing to amplify clarity, drive, and cognitive performance:
1οΈβ£ Dopamine Production & Breakdown (Focus + Motivation) Markers:
TH, DBH, COMT, MAO-A, MAO-B, DRD2
Dopamine drives: βοΈ Motivation
βοΈ Drive
βοΈ Reward
βοΈ Focus
βοΈ Goal pursuit
Imbalances here show up as: β Procrastination
β Brain fog
β Burnout
β ADHD-like symptoms
β Emotional reactivity
If COMT or MAO are slow β dopamine can build up = anxiety & overwhelm.
If production genes are weak β low drive, flat mood, poor concentration.
2οΈβ£ Serotonin Pathway (Emotional Stability + Resilience) Markers: TPH2, DDC, SLC6A4 (serotonin transporter), 5-HTP conversion genes
Serotonin governs: βοΈ Emotional regulation
βοΈ Stress tolerance
βοΈ Sleep quality
βοΈ Confidence
βοΈ Mental steadiness
Disruption = anxiety, irritability, poor sleep, rumination, depression.
3οΈβ£ GABA & Glutamate Balance (Calm Focus vs Mental Overdrive)
Without it: β Racing thoughts
β Overstimulation
β Poor recovery
β Nervous system exhaustion
High performers need calm focus, not adrenaline dependence.
4οΈβ£Detox Enzymes that Regulate Neurotransmitters Markers: GSTP1, GPX, ALDH2, SULT, UGT
These determine how well the brain clears: β Neurotoxins
β Excess neurotransmitters
β Environmental chemicals
β Oxidative stress
If these are impaired β neurotransmitters become unstable β mental chaos.